Results 111 to 120 of about 83,847 (352)

Chronic, Battery‐Free, Fully Implantable Multimodal Spinal Cord Stimulator for Pain Modulation in Small Animal Models

Advanced Science, EarlyView.
This work introduces wireless‐powered fully implantable spinal cord stimulation (SCS) in freely moving animal models, supporting diverse ethological paradigms. kHz stimulation with real‐time digital programming offers versatile, dynamically optimized therapy. Scalable fabrication ensures high N studies and seamless translation.
Allie J. Widman, Taron Bashar, Alex Burton, David Marshall Clausen, Prashant Gupta, Drew K. Wolf, Jakayla Folarin‐Hines, Maria Payne, John A Rogers, Kathleen W. Meacham, Robert W. Gereau, Philipp Gutruf   +11 more
wiley   +1 more source

Effects of the GABA(B) agonist baclofen on volitional swallowing in normal subjects

The Kaohsiung Journal of Medical Sciences, Volume 39, Issue 1, Page 80-86, January 2023., 2023
Abstract The GABA(B) receptor agonist baclofen is known to suppress the rate of spontaneous swallowing but not pharyngeal muscle contraction. The extent to which baclofen may alter volitional swallowing is not currently known. We investigated the effects of baclofen in healthy subjects, hypothesizing that baclofen exposure would alter volume‐regulation
Jui‐Sheng Hung, Shu‐Wei Liang, Taher Omari, Ming‐Wun Wong, Wei‐Yi Lei, Chih‐Hsun Yi, Tso‐Tsai Liu, Lin Lin, Chien‐Lin Chen   +8 more
wiley   +1 more source

Prospects of neuromodulation for chronic pain

Brain Disorders, 2022
Background: For over half a century neuromodulation has been successfully used for treatment of chronic pain syndromes. There is a growing number of new modes or targets of neurostimulation, a widening of indications and continuous improvement in ...
Emil D. Isagulyan, Valentina A. Mikhailova, Karina S. Aslakhanova, Konstantin V. Slavin   +3 more
doaj  

Model-based geometrical optimisation and in vivo validation of a spatially selective multielectrode cuff array for vagus nerve neuromodulation [PDF]

, 2019
Background. Neuromodulation by electrical stimulation of the human cervical vagus nerve may be limited by adverse side effects due to stimulation of off-target organs. It may be possible to overcome this by spatially selective stimulation of peripheral nerves.
arxiv   +1 more source

Micro‐Coil Neuromodulation at Single‐Cell and Circuit Levels for Inhibiting Natural Neuroactivity, Neutralizing Electric Neural Excitation, and Suppressing Seizures

Advanced Science, EarlyView.
Micromagnetic stimulation (µMS) offers a precise method for neural inhibition, complementing existing neuromodulation techniques. Using an implantable micro‐coil device, µMS selectively suppresses cortical activity with high spatial resolution. It effectively counteracts micro‐electrode stimulation and reduces seizure amplitude, highlighting its ...
Kayeon Kim, Xiyuan Liu, Bingdong Chang, Guanghui Li, Gwendoline A. E. Anand, Su Genelioglu, Alexandra Katherine Isis Yonza, Andrew J Whalen, Rune W Berg, Shelley I Fried, Anpan Han, Changsi Cai   +11 more
wiley   +1 more source

Microfabrication Technologies for Nanoinvasive and High‐Resolution Magnetic Neuromodulation

Advanced Science
The increasing demand for precise neuromodulation necessitates advancements in techniques to achieve higher spatial resolution. Magnetic stimulation, offering low signal attenuation and minimal tissue damage, plays a significant role in neuromodulation ...
Changhao Ge, Tahereh Masalehdan, Mahdieh Shojaei Baghini, Vicente Duran Toro, Lorenzo Signorelli, Hannah Thomson, Danijela Gregurec, Hadi Heidari   +7 more
doaj   +1 more source

Chromosome‐Level Genome Assembly of the Leafcutter Bee Megachile rotundata Reveals Its Ecological Adaptation and Pollination Biology

Advanced Science, EarlyView.
The genome of Megachile rotundata, an extensively managed solitary pollination bee species, has been sequenced, covering 280.68 Mb and predicting 10 701 genes. The study reveals significant expansions of the Toll gene family and their abundant expression in diapause prepupae, highlighting enhanced immune responses during diapause. This genome serves as
Rangjun Shi, Pan Duan, Mengmeng Zhu, Rong Zhang, Zihua Zhao, Xin Nie, Hanhou He, Li Hou, Xianhui Wang   +8 more
wiley   +1 more source

Novel Electroactive Therapeutic Platforms for Cardiac Arrhythmia Management

Advanced Science, EarlyView.
Electroactive platforms offer promising applications in cardiac arrhythmia. Based on their energy sources and mechanisms, electroactive platforms are categorized into i) direct electrical stimulation, ii) self‐powered electroactive systems, iii) physical stimuli‐mediated electroactive systems, and iv) conductive systems, and their applications in ...
Juwei Yang, Longfei Li, Yiran Hu, Zhou Li, Wei Hua   +4 more
wiley   +1 more source

Achieving High‐Performance Transcranial Ultrasound Transmission Through Mie and Fano Resonance in Flexible Metamaterials

Advanced Science, EarlyView.
Transcranial ultrasound holds great potential in medical applications. However, effective transcranial ultrasound transmission remains challenging. To address these, this work introduces an innovative Mie‐resonance flexible metamaterial (MRFM), which consists of periodically arranged low‐speed micropillars embedded within a high‐speed flexible ...
Jie Chen, Bing Liu, Genshen Peng, Linming Zhou, Chengwei Tan, Jiale Qin, Juan Li, Zijian Hong, Yongjun Wu, Minghui Lu, Feiyan Cai, Yuhui Huang   +11 more
wiley   +1 more source

Advances in neuromodulation for treatment of prolonged disorders of consciousness

Chinese Journal of Contemporary Neurology and Neurosurgery
Neuromodulation has emerged as a significant clinical treatment modality for patients with prolonged disorders of consciousness (pDOC), encompassing both non⁃invasive and invasive neuromodulation techniques.
HE Chen, SONG Ming, XU Long
doaj   +1 more source