Results 101 to 110 of about 27,995 (224)

Novel optimization of multi‐mechanistic approaches for the acute treatment of a migraine attack: A review

open access: yesHeadache: The Journal of Head and Face Pain, EarlyView.
Abstract Objective To highlight key factors required to optimize multi‐mechanistic approaches with oral combination treatments for the acute management of a migraine attack. Background Given the complex multi‐factorial nature of migraine, combining treatments with different mechanisms of action should improve outcomes compared to monotherapies, but ...
Stephen Silberstein, Alan M. Rapoport
wiley   +1 more source

Modulation of swimming in the gastropod Melibe leonina by nitric oxide [PDF]

open access: yes, 2002
Nitric oxide (NO) is a gaseous intercellular messenger produced by the enzyme nitric oxide synthase. It has been implicated as a neuromodulator in several groups of animals, including gastropods, crustaceans and mammals.
Newcomb, James M.   +1 more
core   +1 more source

Characterisation of sleep apneas and respiratory circuitry in mice lacking CDKL5

open access: yesJournal of Sleep Research, Volume 34, Issue 2, April 2025.
Summary CDKL5 deficiency disorder is a rare genetic disease caused by mutations in the CDKL5 gene. Central apneas during wakefulness have been reported in patients with CDKL5 deficiency disorder. Studies on CDKL5‐knockout mice, a CDKL5 deficiency disorder model, reported sleep apneas, but it is still unclear whether these events are central (central ...
Gabriele Matteoli   +12 more
wiley   +1 more source

Useful considerations for treating migraine in patients with autism. [PDF]

open access: yesHeadache
Headache: The Journal of Head and Face Pain, Volume 66, Issue 3, Page 768-770, March 2026.
Nwaobi SE.
europepmc   +2 more sources

Sleep Macrostructure, Cyclic Alternating Pattern and CSF Cytokines in De Novo Relapsing–Remitting Multiple Sclerosis: A Controlled Polysomnographic Study

open access: yesJournal of Sleep Research, EarlyView.
ABSTRACT Multiple sclerosis is frequently associated with sleep disorders. This study aimed to evaluate subjective and objective sleep parameters in de novo relapsing–remitting multiple sclerosis patients compared to healthy controls and to explore correlations with cerebrospinal fluid cytokines.
A. Romigi   +10 more
wiley   +1 more source

Checks and balances in neuromodulation

open access: yesFrontiers in Behavioral Neuroscience, 2010
Neuromodulators such as monoamines and peptides play important roles in activating and reconfiguring neural networks to allow behavioral flexibility. While the net effects of a neuromodulator change the network in a particular direction, careful studies ...
Ronald M Harris-Warrick   +1 more
doaj   +1 more source

Imaging striatal dopamine release using a nongenetically encoded near infrared fluorescent catecholamine nanosensor. [PDF]

open access: yes, 2019
Neuromodulation plays a critical role in brain function in both health and disease, and new tools that capture neuromodulation with high spatial and temporal resolution are needed.
Beyene, Abraham G   +11 more
core   +1 more source

Beyond Malabsorption: The Need for Symptom‐Based Assessment in Suspected Lactose Intolerance. Lessons From a Test‐Specific Symptom Assessment

open access: yesNeurogastroenterology &Motility, EarlyView.
Breath test–proven malabsorption does not reliably predict symptoms. Many patients without malabsorption still develop significant symptoms. Symptoms after lactose ingestion are linked to fructose sensitivity and functional GI disorders. Validated, test‐specific symptom assessment is required to identify patients who may benefit from treatment ...
Johann Hammer, Heinz F. Hammer
wiley   +1 more source

The Effect of Micro-Focused Ultrasound Treatment on Intradermal Botulinum Toxin Type A Injection

open access: yesToxins
Botulinum toxin type A (BoNT-A) injection and micro-focused ultrasound with visualization (MFU-V) are becoming increasingly popular for various esthetic conditions.
Sarawin Harnchoowong   +2 more
doaj   +1 more source

Play in Cognitive Development: From Rational Constructivism to Predictive Processing

open access: yesTopics in Cognitive Science, EarlyView.
Abstract It is widely believed that play and curiosity are key ingredients as children develop models of the world. There is also an emerging consensus that children are Bayesian learners who combine their structured prior beliefs with estimations of the likelihood of new evidence to infer the most probable model of the world.
Marc M. Andersen, Julian Kiverstein
wiley   +1 more source

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