Results 111 to 120 of about 112,795 (235)

Spasmodic Dysphonia

open access: yesWorld Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Spasmodic dysphonia is a laryngeal dystonia that can present as adductor, abductor, or mixed types, with or without tremor. The etiology is not understood fully. Comprehensive evaluation is required to establish the diagnosis. Treatments include voice therapy, medications, botulinum toxin injection, laryngeal surgery, deep brain stimulation ...
Aaron J. Jaworek, Robert T. Sataloff
wiley   +1 more source

The use of an ultrasound-guided popliteal block for hallux valgus surgery in a patient with myasthenia gravis [PDF]

open access: yes, 2013
Myasthenia gravis (MG) is an autoimmune disease which affects neuromuscular transmission, causing muscle fatigue and weakness(1).The myasthenic patients are always a challenge to the anesthesiologist, because they demonstrate various responses to the ...
DANIJELA GULAM   +4 more
core   +1 more source

Genetic and Pharmacological Inhibition of Metabotropic Glutamate Receptor Signalling Extends Lifespan in Drosophila

open access: yesAging Cell, Volume 24, Issue 5, May 2025.
We show that genetic and pharmacological inhibition of the metabotropic glutamate receptor, DmGluRA extends Drosophila lifespan, improves stress tolerance and alters early‐life locomotion. Several markers indicative of reduced ribosomal biogenesis, a hallmark of longevity, were also detected in these flies.
Cui Guan   +4 more
wiley   +1 more source

How hard is it to satisfy (almost) all roommates? [PDF]

open access: yesarXiv, 2017
The classic Stable Roommates problem (which is the non-bipartite generalization of the well-known Stable Marriage problem) asks whether there is a stable matching for a given set of agents, i.e. a partitioning of the agents into disjoint pairs such that no two agents induce a blocking pair.
arxiv  

A comparative study of different induction techniques (Propofol-Placebo, Propofol-Ephedrine and Propofol- Placebo-Crystalloid) on intubating conditions after rocuronium administration [PDF]

open access: yes, 2007
This was a prospective randomized double blind controlled study to compare intubating conditions at 60 seconds with rocuronium 0.6 mg/kg by using three different induction techniques: propofol-placebo (PP), propofol-ephedrine (PE) and propofol ...
Karis Misiran,, Muhd Helmi Azmi,
core  

Nuclear Import Defects Drive Cell Cycle Dysregulation in Neurodegeneration

open access: yesAging Cell, EarlyView.
Overview of Dysregulated Cell Cycle Mechanisms in Neuronal Cells. A nuclear import block drives cell cycle re‐entry from G0, culminating in cell cycle arrest at G1/S. This cell cycle arrest is associated with activation of CKIs from the INK locus (p15, p16, p18, p19) and Cip/Kip (p21, p27) which act on specific CDK/Cyclin complexes.
Jonathan Plessis‐Belair   +3 more
wiley   +1 more source

PushPush is NP-hard in 3D [PDF]

open access: yesarXiv, 1999
We prove that a particular pushing-blocks puzzle is intractable in 3D. The puzzle, inspired by the game PushPush, consists of unit square blocks on an integer lattice. An agent may push blocks (but never pull them) in attempting to move between given start and goal positions.
arxiv  

Endotypes in Immune Mediated Drug Reactions: Present and Future of Relevant Biomarkers. An EAACI Task Force Report

open access: yesAllergy, EarlyView.
ABSTRACT Drug‐induced immune reactions are an important burden for patients and health systems. They can be classified into immediate‐drug hypersensitivity reactions (IDHRs) and delayed‐DHRs (DDHRs) based on their phenotype. Drugs do not always behave as allergens and need to bind to proteins, forming adducts.
C. Mayorga   +7 more
wiley   +1 more source

Trends in the use of neuromuscular blocking agents, reversal agents and neuromuscular transmission monitoring: a single-centre retrospective cohort study

open access: yesPerioperative Medicine
Background Residual neuromuscular blockade (rNMB) remains a persistent and preventable problem, with serious risks. Methods Our objective was to describe and assess patterns in the use of neuromuscular blocking agents (NMBAs), neuromuscular transmission (
Piet Krijtenburg   +5 more
doaj   +1 more source

PushPush is NP-hard in 2D [PDF]

open access: yesarXiv, 2000
We prove that a particular pushing-blocks puzzle is intractable in 2D, improving an earlier result that established intractability in 3D [OS99]. The puzzle, inspired by the game *PushPush*, consists of unit square blocks on an integer lattice. An agent may push blocks (but never pull them) in attempting to move between given start and goal positions ...
arxiv  

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