Results 211 to 220 of about 98,850 (323)

Ofatumumab-mediated CD20⁺ B-cell depletion promotes neuromuscular junction functional recovery and sustains long-term efficacy in refractory generalized myasthenia gravis. [PDF]

Front Pharmacol
Ren Z, Chen Y, Liu Y, Wang Y, Xu S, Yang Y, Qiu F.   +6 more
europepmc   +1 more source

Anticholinergic Burden and Botulinum Toxin Needs after Deep Brain Stimulation in Adult and Pediatric Patients with Dystonia

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Anticholinergic medications and botulinum neurotoxin injections are established treatments for dystonia, yet they carry potential side effects and practical challenges. Deep brain stimulation (DBS) is offered in case of poor response to these approaches.
Marcela A. Montiel, Alessandro Magliozzi, Wei Kang Lim, Carolina Gorodetsky, George M. Ibrahim, Alfonso Fasano   +5 more
wiley   +1 more source

Monitoring of Neuromuscular Junction.

Indian Journal of Anaesthesia, 2002
D Padmaja, Srinivas Mantha
doaj  

Electron Microscopical Study on the Fine Structure and the Cholinesterase Activity of the Neuromuscular Junction in Progressive Muscular Dystrophy

, 1965
Takashi Nara
openalex   +1 more source

Neuron-specific Agrin splicing by Nova RNA-binding proteins regulates conserved neuromuscular junction development in chordates. [PDF]

PLoS Biol
Hossain MF, Popsuj S, Vitrinel B, Kaplan NA, Stolfi A, Christiaen L, Ruggiu M.   +6 more
europepmc   +1 more source

Single‐Cell Transcriptomic Analysis Reveals Epithelial‐Mesenchymal Transition and Key Gene AGRN as a Universal Programme in Gastrointestinal Tumours by an Artificial Intelligence‐Derived Prognostic Index

Med Research, EarlyView.
Intra‐tumour heterogeneity is present in gastrointestinal tumours at the single‐cell level. Cell cycling, EMT, MYC and TNF‐α are the four main consensus meta‐programs in gastrointestinal tumours. Then, a prognostic model based on intratumoral heterogeneity was constructed using an artificial intelligence‐derived prognostic index.
Zhizhan Ni, Pengyuan Zhu, Liming Liu, Haiyang Wang, Jinzhe Zhou, Xianqing Wang, Song Wang, Liangchen Zhu, Songze Zhang, Yongxin Zhou, Bujun Ge, Qi Huang, Chenshen Huang   +12 more
wiley   +1 more source

Identification of an intracellular postsynaptic antigen at the frog neuromuscular junction. [PDF]

, 1982
Steven J. Burden
openalex   +1 more source

Nipocalimab‐aahu (IMAAVY) for Generalized Myasthenia Gravis: Redefining Treatment With FcRn Inhibition

Medicine Advances, EarlyView.
FDA approval of IMAAVY (nipocalimab) marks a major advancement in the management of generalized myasthenia gravis (gMG). Clinical trial data showed significant improvements in MG‐ADL scores, especially in AChR‐positive patients, while also highlighting its favorable safety profile, potential for subcutaneous self‐administration, and greater ...
Muhammad Affan Abid, Malaika Manzoor, Reham Jamal, Humaiz Ahmed   +3 more
wiley   +1 more source

Sarcoglycans are enriched at the neuromuscular junction in a nerve-dependent manner. [PDF]

Cell Death Dis
Gloriani M, Cheli B, D'Ercole C, Ruggieri V, Cosentino M, Serrat Pineda M, Lozanoska-Ochser B, Grassi F, Bouché M, Madaro L, Sánchez Riera C.   +10 more
europepmc   +1 more source

A Psychometric Evaluation of Maximum Phonation Time and S/Z Ratio as Pragmatic Outcome Measures of Bulbar Function in Adults With Spinal Muscular Atrophy

Muscle &Nerve, EarlyView.
ABSTRACT Introduction/Aims A pragmatic evaluation of bulbar function among adults with spinal muscular atrophy (awSMA) is needed, requiring the validation of a low‐cost, feasible outcome measure (OM). Maximum phonation time (MPT) and S/Z ratio (S/Z) are potential low‐cost OMs for bulbar function. This study aimed to evaluate the psychometric properties
Jeremy Slayter, Lauren Casey, Dorothy Drost, Shane McCullum, Allison Christie, Colleen O'Connell   +5 more
wiley   +1 more source