Results 31 to 40 of about 615,784 (234)
Denervation-Related Neuromuscular Junction Changes: From Degeneration to Regeneration
Frontiers in Molecular Neuroscience, 2022 Neuromuscular junctions (NMJs) are the key interface between terminal nerves and targeted muscle, which undergo degeneration during denervation periods. Denervation-related NMJs changes limits the recovery level of nerve repair strategies.
Xinying Huang +9 more
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Synapse development and maturation at the drosophila neuromuscular junction
Neural Development, 2020 Synapses are the sites of neuron-to-neuron communication and form the basis of the neural circuits that underlie all animal cognition and behavior. Chemical synapses are specialized asymmetric junctions between a presynaptic neuron and a postsynaptic ...
Vivian T. Chou +2 more
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Rejuvenation of the aged neuromuscular junction by exercise
Cell Stress, 2018 Age-dependent declines in muscle function are observed across species. The loss of mobility resulting from the decline in muscle function represents an important health issue and a key determinant of quality of life for the elderly.
Tabita Kreko-Pierce, Benjamin A. Eaton
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Juvenile Neuromuscular Systems Show Amplified Disturbance to Muscle Unloading
Frontiers in Physiology, 2021 Muscle unloading results in severe disturbance in neuromuscular function. During juvenile stages of natural development, the neuromuscular system experiences a high degree of plasticity in function and structure.
Michael R. Deschenes +5 more
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NAD+ improves neuromuscular development in a zebrafish model of FKRP-associated dystroglycanopathy
Skeletal Muscle, 2019 Background Secondary dystroglycanopathies are muscular dystrophies that result from mutations in genes that participate in Dystroglycan glycosylation.
Erin C. Bailey +9 more
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Neural Regeneration Research, 2016 Myasthenia gravis is an autoimmune disorder in which antibodies have been shown to form against the nicotinic acetylcholine nicotinic postsynaptic receptors located at the neuromuscular junction.
Hai-peng Huang, Hong Pan, Hong-feng Wang
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Frontiers in Molecular Neuroscience, 2022 Muscle-specific kinase (MuSK) is a receptor tyrosine kinase absolutely required for neuromuscular junction formation. MuSK is activated by binding of motor neuron-derived Agrin to low-density lipoprotein receptor related protein 4 (Lrp4), which forms a ...
Anna Gemza +5 more
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Myasthenia gravis: the role of complement at the neuromuscular junction
Annals of the New York Academy of Sciences, 2018 Generalized myasthenia gravis (gMG) is a rare autoimmune disorder characterized by skeletal muscle weakness caused by disrupted neurotransmission at the neuromuscular junction (NMJ).
J. Howard
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Frontiers in Physiology, 2021 Recent studies have demonstrated that neuromuscular junctions are co-innervated by sympathetic neurons. This co-innervation has been shown to be crucial for neuromuscular junction morphology and functional maintenance. To improve our understanding of how
Tatjana Straka +17 more
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Neuromuscular Junction as an Entity of Nerve-Muscle Communication
Cells, 2019 One of the crucial systems severely affected in several neuromuscular diseases is the loss of effective connection between muscle and nerve, leading to a pathological non-communication between the two tissues.
E. Lepore +3 more
semanticscholar +1 more source