Facilitatory actions of guanidine on synaptic transmission in mammalian brain slices [PDF]
, 1979 Guanidine administration may be beneficial in the treatment of amyotrophic lateral sclerosis and related diseases; however, the actions of guanidine on the mammalian central nervous system have not been investigated.
Galvan, Martin +2 more
core +1 more source
Role of Neuromuscular Junction Monitoring in Management of a Postpartum Eclamptic Patient with Iatrogenic Hypermagnesemia [PDF]
The Indian Anaesthetists' Forum, 2010 Accidental hypermagnesemia is a common and often missed complication during treatment in a postpartum eclamptic patient. As symptomatic hypermagnesemia leads to neuromuscular junction blockade, neuromuscular junction monitoring serves the purpose of ...
Harshel G Parikh, Chitra B Upasani
doaj
Activity-dependent plasticity of transmitter release from nerve terminals in rat fast and slow muscles [PDF]
, 2018 Available under a Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported license.Peer reviewedPublisher ...
Bewick, Guy Smith +4 more
core +1 more source
Age-related deficits in skeletal muscle recovery following disuse are associated with neuromuscular junction instability and ER stress, not impaired protein synthesis. [PDF]
, 2016 Age-related loss of muscle mass and strength can be accelerated by impaired recovery of muscle mass following a transient atrophic stimulus. The aim of this study was to identify the mechanisms underlying the attenuated recovery of muscle mass and ...
Baar, Keith +6 more
core +2 more sources
Neural Regeneration ResearchMitochondrial dysfunction and oxidative stress are widely regarded as primary drivers of aging and are associated with several neurodegenerative diseases.
Senlin Chai +10 more
doaj +1 more source
Review: Dystroglycan in the Nervous System [PDF]
, 2007 Dystroglycan is part of a large complex of proteins, the dystrophin-glycoprotein complex, which has been implicated in the pathogenesis of muscular dystrophies for a long time.
Matthias Samwald
core +2 more sources
Cell Reports, 2019 Summary: Age-related loss of skeletal muscle innervation by motor neurons leads to impaired neuromuscular function and is a well-established clinical phenomenon. However, the underlying pathogenesis remains unclear. Studying mice, we find that the number
Elisa Giorgetti +18 more
doaj +1 more source
Glutamate at the Vertebrate Neuromuscular Junction: From Modulation to Neurotransmission
Cells, 2019 Although acetylcholine is the major neurotransmitter operating at the skeletal neuromuscular junction of many invertebrates and of vertebrates, glutamate participates in modulating cholinergic transmission and plastic changes in the last.
Maria Nicol Colombo, Maura Francolini
doaj +1 more source
The impact of Hnrnpl deficiency on transcriptional patterns of developing muscle cells
FEBS Open Bio, EarlyView.We performed nanopore whole‐transcriptome sequencing comparing RNA from Hnrnpl‐knockdown versus control C2C12 myoblasts to investigate the contributions of Hnrnpl to muscle development. Our results indicate that Hnrnpl regulates the expression of genes involved with Notch signaling and skeletal muscle, particularly splicing patterns of specific muscle ...
Hannah R. Littel +8 more
wiley +1 more source
Flow cytofluorimetric analysis of anti-LRP4 (LDL receptor-related protein 4) autoantibodies in Italian patients with Myasthenia gravis [PDF]
, 2015 Background: Myasthenia gravis (MG) is an autoimmune disease in which 90% of patients have autoanti-bodies against the muscle nicotinic acetylcholine receptor (AChR), while autoantibodies to muscle-specific tyrosine kinase (MuSK) have been detected in ...
Antonini, Giovanni +11 more
core +9 more sources