Results 41 to 50 of about 666,453 (371)

A functional motor unit in the culture dish : co-culture of spinal cord explants and muscle cells [PDF]

open access: yes, 2012
Human primary muscle cells cultured aneurally in monolayer rarely contract spontaneously because, in the absence of a nerve component, cell differentiation is limited and motor neuron stimulation is missing(1). These limitations hamper the in vitro study
Arnold, Anne-Sophie   +2 more
core   +1 more source

Myasthenia gravis: the role of complement at the neuromuscular junction

open access: yesAnnals of the New York Academy of Sciences, 2018
Generalized myasthenia gravis (gMG) is a rare autoimmune disorder characterized by skeletal muscle weakness caused by disrupted neurotransmission at the neuromuscular junction (NMJ).
J. Howard
semanticscholar   +1 more source

Regulatory Function of Sympathetic Innervation on the Endo/Lysosomal Trafficking of Acetylcholine Receptor

open access: yesFrontiers in Physiology, 2021
Recent studies have demonstrated that neuromuscular junctions are co-innervated by sympathetic neurons. This co-innervation has been shown to be crucial for neuromuscular junction morphology and functional maintenance. To improve our understanding of how
Tatjana Straka   +17 more
doaj   +1 more source

DOXAPRAM AND THE NEUROMUSCULAR JUNCTION †

open access: yesBritish Journal of Anaesthesia, 1989
We have studied the action of doxapram on neuromuscular transmission in the rat phrenic nerve-diaphragm preparation. Doxapram augmented neuromuscular transmission in a dose-related manner when a threshold concentration of 5 x 10(-5) mol litre-1 had been exceeded.
Barbara J. Pleuvry   +2 more
openaire   +3 more sources

Presynaptic facilitation at the crayfish neuromuscular junction: Role of calcium-activated potassium conductance [PDF]

open access: yes, 1991
Membrane potential was recorded intracellularly near presynaptic terminals of the excitor axon of the crayfish opener neuromuscular junction (NMJ), while transmitter release was recorded postsynaptically.
Bittner, George D.   +2 more
core   +1 more source

Neuromuscular Junction as an Entity of Nerve-Muscle Communication

open access: yesCells, 2019
One of the crucial systems severely affected in several neuromuscular diseases is the loss of effective connection between muscle and nerve, leading to a pathological non-communication between the two tissues.
E. Lepore   +3 more
semanticscholar   +1 more source

Neuromuscular Junction Disorders

open access: yesDeckerMed Medicine, 2002
The three main components of the neuromuscular junction (NMJ) include the presynaptic region, the synaptic cleft, and the postsynaptic region. The NMJ acts as an interface between the motor nerve and muscle by converting the motor nerve electric currents into chemical signals and then back into electric currents in the muscle.
Mohammad Salajegheh, Anthony A. Amato
openaire   +2 more sources

THE NEUROMUSCULAR JUNCTION DISORDERS [PDF]

open access: yesJournal of Neurology, Neurosurgery & Psychiatry, 2003
Neuromuscular junction (NMJ) disorders result from destruction, malfunction or absence of one or more key proteins involved in neuromuscular transmission, illustrated diagrammatically in fig 1. The most common pathology is antibody mediated damage or down regulation of ion channels or receptors, resulting in myasthenia gravis (MG), Lambert-Eaton ...
openaire   +3 more sources

Nitric oxide regulates skeletal muscle fatigue, fiber type, microtubule organization, and mitochondrial ATP synthesis efficiency through cGMP-dependent mechanisms [PDF]

open access: yes, 2016
Aim: Skeletal muscle nitric oxide–cyclic guanosine monophosphate (NO-cGMP) pathways are impaired in Duchenne and Becker muscular dystrophy partly because of reduced nNOSμ and soluble guanylate cyclase (GC) activity.
Balke, Jordan E   +8 more
core   +1 more source

Role of Neuromuscular Junction Monitoring in Management of a Postpartum Eclamptic Patient with Iatrogenic Hypermagnesemia [PDF]

open access: yesThe Indian Anaesthetists' Forum, 2010
Accidental hypermagnesemia is a common and often missed complication during treatment in a postpartum eclamptic patient. As symptomatic hypermagnesemia leads to neuromuscular junction blockade, neuromuscular junction monitoring serves the purpose of ...
Harshel G Parikh, Chitra B Upasani
doaj  

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