Results 231 to 240 of about 49,589 (307)

Epigenetic modulation of the gut-muscle axis in pompe disease: Microbiota fingerprints to cellular and molecular pathomechanisms. [PDF]

Mol Metab
Venezia M, Russo M, Colomba P, Zizzo C, Vinci M, Marsana EM, D'Errico A, Giacalone I, Duro G, Moschetti M.   +9 more
europepmc   +1 more source

Human‐derived cardiac‐neural microtissues reveal catecholaminergic polymorphic ventricular tachycardia is also a disease of the sympathetic neuron

The Journal of Physiology, EarlyView.
Abstract figure legend Schematic diagram illustrating the proposed pathway in which regulatory defects might occur in sympathetic neurons derived from hiPSC in catecholaminergic polymorphic ventricular tachycardia (CPVT). Specifically, enhanced calcium transients appeared to derive from three sources: enhanced membrane excitability (due to loss of ...
Ni Li, Chenchen Zhang, Mengying Xu, YoonYoung Choi, Davi Sidarta‐Oliveira, Ruirui Dong, Xinyu Hu, Enrique M. Toledo, Cesar A. Prada‐Medina, Finbar Argus, Kun Liu, Mingyu Li, Linna Zhou, Hagan Bayley, Corey Smith, Chris Denning, Ana I. Domingos, Guoliang Hao, Dan Li, David J. Paterson   +19 more
wiley   +1 more source

Review of the Pathology of Muscle in Amyotrophic Lateral Sclerosis. [PDF]

Int J Mol Sci
Katz M, Robertson T, Ngo ST, Yarlagadda S, Henderson RD, McCombe PA, Noakes PG.   +6 more
europepmc   +1 more source

Stac2 genetic deletion alters mouse chromaffin cells’ CaV channel composition, increases membrane excitability and reduces vesicle exocytosis

The Journal of Physiology, EarlyView.
Abstract figure legend Stac2 adaptor protein is expressed in neurons and endocrine cells. Using a global Stac2 knockout mouse model here we investigated the role of endogenous Stac2 in adrenal gland mouse chromaffin cell (MCC) excitability and catecholamine vesicle exocytosis.
Stefanie M. Geisler, Noelia Jacobo‐Piqueras, Tamara Theiner, Ryoichi S. Taguchi, Laura E. Häfele, Marta Campiglio, Petronel Tuluc   +6 more
wiley   +1 more source

Comprehensive Review of Anesthetic Strategies for Patients With Neurodegenerative Diseases. [PDF]

Med Sci Monit
Grabarczyk Ł.
europepmc   +1 more source

Characterization of postnatal brain injury and behavioural deficits in a rat model of placental insufficiency‐induced fetal growth restriction

The Journal of Physiology, EarlyView.
Abstract figure legend Fetal growth restriction (FGR) is a common pregnancy complication associated with long‐term neurodevelopmental impairments. Using the reduced uterine perfusion pressure (RUPP) rat model of placental insufficiency‐induced FGR, this study demonstrates that FGR leads to persistent anatomical, histological and behavioural ...
Judit Alhama‐Riba, Caroline G. M. de Theije, Valentina Salvi, Dominique Viveen, Sebastiaan W. T. Corstjens, Marijke. E. J. Achterberg, Yohan van de Looij, Freek E. Hoebeek, Cora H. A. Nijboer   +8 more
wiley   +1 more source

Exploring molecular signatures in PURA syndrome using muscle proteomics and serum biomarkers. [PDF]

J Neurol
Mroczek M, Preusse C, Hentschel A, Chrościńska-Krawczyk M, Bielak M, Sobolewska A, Della Marina A, Hila A, Iyadurai S, Kraft F, Chetty VK, Muhmann D, Ruck T, Goebel HH, Schara-Schmidt U, Dobelmann V, Thakur BK, Stenzel W, Roos A.   +18 more
europepmc   +1 more source

Oleuropein‐based olive leaf extract enhances muscle mitochondrial bioenergetics response to moderate – but not maximal – intensity exercise in humans

The Journal of Physiology, EarlyView.
Abstract figure legend In a double‐blind, crossover study, we observed that olive leaf extract (OLE) intake combined with a single session of moderate‐intensity continuous exercise (MICE) significantly enhanced skeletal muscle mitochondrial bioenergetics, whereas this effect was milder when OLE was combined with sprint interval exercise (SIE ...
Clément Lanfranchi, Alba Moreno‐Asso, Astrid M. H. Horstman, Sara Mistro, Eugenia Migliavacca, Ornella Cominetti, Jens Stolte, Sylviane Métairon, Aurélie Hermant, Ane Laura Pedersen, Loïc Dayon, Umberto De Marchi, Jérôme N. Feige, Nadège Zanou, Nicolas Place   +14 more
wiley   +1 more source

Novel Translational Concept: Axon-to-Muscle Exosomal Signaling as an Emerging Therapeutic Target in Spinal Muscular Atrophy. [PDF]

Biomedicines
Fajkić A, Belančić A, Lam YW, Rački V, Pilipović K, Janković T, Mežnarić S, Mršić-Pelčić J, Vitezić D.   +8 more
europepmc   +1 more source

Alpha-synuclein as a regulator of synaptic signalling [PDF]

Pelkonen, Anssi
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