Results 51 to 60 of about 32,201 (250)

Neuromyelitis optica

Annals of Indian Academy of Neurology, 2006
Neuromyelitis optica (NMO) or Devic′s disease was until recently regarded as an unusual or severe variant of multiple sclerosis. However the last decade has seen major advances in our understanding of the etiopathogenesis of NMO. Though unsettled, there seems to be increasing evidence that NMO is a distinct immune mediated, largely relapsing ...
Jacob Anu, Boggild Mike
openaire   +2 more sources

Familial neuromyelitis optica [PDF]

Neurology, 2010
Detection of aquaporin-4-specific immunoglobulin G (IgG) has expanded the spectrum of neuromyelitis optica (NMO). Rare reports of familial aggregation have suggested a component of genetic susceptibility but these reports mostly antedated the discovery of the NMO-IgG biomarker and recently updated diagnostic criteria.We report a case series describing ...
Marcelo Matiello, Ho Jin Kim, Doralina Guimarães Brum, Amilton Antunes Barreira, D.J. Kingsbury, Brian G. Weinshenker, G.T. Plant, W. Kim, T. Adoni   +8 more
openaire   +3 more sources

Treatment of neuromyelitis optica: state-of-the-art and emerging therapies. [PDF]

, 2014
Neuromyelitis optica (NMO) is an autoimmune disease of the CNS that is characterized by inflammatory demyelinating lesions in the spinal cord and optic nerve, potentially leading to paralysis and blindness.
A Bar-Or, A Davies, A Iyer, A Jacob, A Jacob, A Jacob, A Jacob, A McKeon, A Nagaishi, A Rossi, A Uzawa, A Warth, AE Damiano, Alan S. Verkman, AMC Faria, B Banwell, B Bielekova, B Bourre, B Weinstock-Guttman, BA Cree, BC Kieseier, BG Weinshenker, BL Raveendra, BM Greenberg, BM Greenberg, C Costanzi, C Trebst, C Wrzos, CF Lucchinetti, CH Polman, D Ricklin, D Ricklin, D Yuksel, DB Bichuetti, DB Bichuetti, DG Brum, DJ Kimbrough, DK Sato, DM Wingerchuk, DM Wingerchuk, E Gomori, EW Gelfand, F Shimizu, G Pentón-Rol, GG Illei, GS Bedi, H Kita, H Merle, H Wang, H Wen, H Yaguchi, H Zephir, H Zhang, H Zhang, HH Wang, HL Pellkofer, HL Pellkofer, HL Pellkofer, HM Reeves, I Ayzenberg, I Kleiter, I Kleiter, I Nakashima, J Bakker, J Fagius, J Kitley, J Kitley, J Kitley, J Kitley, J Kitley, J Kitley, J Palace, J Ratelade, J Ratelade, J Ratelade, J Ratelade, J Shimizu, JA Cabrera-Gomez, Jeffrey L. Bennett, JH Min, JL Bennett, JM Crane, JM Tillema, JR Faulkner, JS Wu, K Iwata, K Kawabata, K Miyamoto, K Okada, K Rostasy, K Sugita, KR Carson, L Elsone, L Tradtrantip, L Tradtrantip, L Tradtrantip, L Tradtrantip, LA Lewis, M Araki, M Barnett, M Bonnan, M Bonnan, M Botto, M Bradl, M Collin, M De Falco, M Keegan, M Koga, M Matiello, M Matiello, M Pohl, M Reindl, M Ringelstein, M Varrin-Doyer, MA Mealy, MA Sahraian, Marios C. Papadopoulos, MC Papadopoulos, MJ Magraner, N Asavapanumas, N Asavapanumas, N Asgari, N Chihara, N Chihara, N Muls, O Hammer, P Cabre, P Huppke, P Imbach, PF Zipfel, PJ Barnes, PW Phuan, PW Phuan, PW Phuan, R Deschamps, R Reuss, RC Axtell, RE Young, RR Voskuhl, S Izaki, S Jacob, S Jarius, S Jarius, S Jarius, S Jarius, S Jarius, S Jarius, S Jarius, S Kim, S Mader, S Mihai, S Saadoun, S Saadoun, S Saadoun, S Saadoun, S Saadoun, S Saadoun, S Watanabe, S-H Kim, S-H Kim, S-H Kim, S-H Kim, SH Kim, SJ Pittock, SR Hinson, SR Hinson, SR Hinson, SR Kalluri, T Hosokawa, T Kageyama, T Matsuoka, T Matsushita, T Vincent, TE Lotze, TF Tedder, UC Linhares, V Papayannopoulos, VA Lennon, VA Lennon, VT Chu, W Kim, Y Li, Y Warabi, YD Fragoso   +183 more
core   +1 more source

Neuromyelitis optica spectrum disorder with AQP4‐IgG presenting as area postrema syndrome and progressing to myelitis: A rare case report

Clinical Case Reports, 2023
Key Clinical Message Neuromyelitis optica spectrum disorders can less commonly present with area postrema syndrome progressing to myelitis. Management involves intravenous glucocorticoids, plasma exchange, and preventive immunotherapy.
Preethi Jagannath, Mohammed Suhail K, Shaikh Mohammed Aslam S, Ashwin Kulkarni, Polasu Sri Satya Sai Prashanth, Hritik Madan, Ayush Anand   +6 more
doaj   +1 more source

Diagnosis and treatment of NMO spectrum disorder and MOG-encephalomyelitis [PDF]

, 2018
Neuromyelitis optica spectrum disorders (NMOSD) are autoantibody mediated chronic inflammatory diseases. Serum antibodies (Abs) against the aquaporin-4 water channel lead to recurrent attacks of optic neuritis, myelitis and/or brainstem syndromes.
Borisow, Nadja, Kuwabara, Satoshi, Mori, Masahiro, Paul, Friedemann, Scheel, Michael   +4 more
core   +2 more sources

Alemtuzumab use in neuromyelitis optica spectrum disorders: a brief case series. [PDF]

, 2016
Alemtuzumab is an anti-CD52 monoclonal antibody recently licensed for use in relapsing-remitting multiple sclerosis. Here, we report our experience of its use in neuromyelitis optica (NMO) spectrum disorders.
Azzopardi, L, Coles, AJ, Cox, AL, Jones, JL, McCarthy, CL   +4 more
core   +1 more source

Therapeutic decision making in autoimmune and inflammatory disorders of the central nervous system in children. [PDF]

, 2016
Autoimmune and inflammatory disorders of the central nervous system can result in significant morbidity and mortality. Through the recognition of syndromes using diagnostic biomarkers, the clinician is now able to use immune suppressive therapies to ...
Dale, Rc, Lim, M., Nosadini, M
core   +3 more sources

Aquaporin-4-IgG-seropositive neuromyelitis optica spectrum disorders: progress of experimental models based on disease pathogenesis

Neural Regeneration Research
Neuromyelitis optica spectrum disorders are neuroinflammatory demyelinating disorders that lead to permanent visual loss and motor dysfunction. To date, no effective treatment exists as the exact causative mechanism remains unknown.
Li Xu, Huiming Xu, Changyong Tang
doaj   +1 more source

Eculizumab‐related drug reaction in a patient with neuromyelitis optica

Clinical Case Reports, 2023
Eculizumab is approved for treatment of antibody positive neuromyelitis optica, myasthenia gravis, and hematologic disorders like paroxysmal nocturnal hemoglobinuria. Drug rash has not yet been reported as a side effect of eculizumab. We report a case of
Rishi Sharma, Moises Romo, Flavia Nelson
doaj   +1 more source

Neuromyelitis optica spectrum disorder in three generations of a Chinese family [PDF]

, 2019
© 2019 Neuromyelitis optica spectrum disorder is an inflammatory demyelinating disease that is largely sporadic. Familial disease has been reported in one or two generations, although its basis remains unknown.
Dalton, Caroline, Fachim, H.A., Luo, Z., Reynolds, G.P., Sun, P., Wei, X., Yang, W., Zhang, S.   +7 more
core   +1 more source