Results 81 to 90 of about 32,201 (250)

Effects of physical therapy intervention in the management of neuromyelitis optica: a case report

Bulletin of Faculty of Physical Therapy, 2023
Background Neuromyelitis optica is a rare immune-mediated demyelinating central nervous system disorder affecting the spinal cord and optic nerves. There is no permanent cure for this disease, and its management requires a multidisciplinary approach ...
Sneha Chakraverty, Sayak Dutta, Himadri Das   +2 more
doaj   +1 more source

Anti-aquaporin 4 IgG Is Not Associated With Any Clinical Disease Characteristics in Neuromyelitis Optica Spectrum Disorder

Frontiers in Neurology, 2021
Background: Neuromyelitis optica spectrum disorder (NMOSD) is a clinically defined, inflammatory central nervous system (CNS) disease of unknown cause, associated with humoral autoimmune findings such as anti-aquaporin 4 (AQP4)-IgG.
Oliver Schmetzer, Oliver Schmetzer, Oliver Schmetzer, Elisa Lakin, Elisa Lakin, Elisa Lakin, Ben Roediger, Ankelien Duchow, Ankelien Duchow, Ankelien Duchow, Susanna Asseyer, Susanna Asseyer, Susanna Asseyer, Friedemann Paul, Friedemann Paul, Friedemann Paul, Nadja Siebert, Nadja Siebert, Nadja Siebert   +18 more
doaj   +1 more source

Plasma complement biomarkers distinguish multiple sclerosis and neuromyelitis optica spectrum disorder [PDF]

, 2016
Background: Multiple sclerosis (MS) and neuromyelitis optica spectrum disorders (NMOSD) are autoimmune demyelinating diseases distinguished clinically by selective involvement in NMOSD of optic nerves and spinal cord. Early clinical manifestations are
Evans, David R. S., Hakobyan, Svetlana, Harding, Katharine, Loveless, Samantha, Luppe, Sebastian, Morgan, Bryan Paul, Robertson, Neil P.   +6 more
core   +1 more source

Evolving Real‐World Data and Evidence Use for New Drugs and Regenerative Medical Products Approvals in Japan—An Analysis of the 6‐Year Trend

Clinical Pharmacology &Therapeutics, EarlyView.
Several regulatory initiatives have been made to clarify the acceptability and requirements of real‐world data and real‐world evidence (RWD/E) for the benefit/risk assessment of new medical products in Japan. The objectives of this review were to characterize the use of RWD/E in regulatory applications of new medical products and to describe the ...
Suguru Okami, Kako Shimotsumagari, Yasunari Sadatsuki   +2 more
wiley   +1 more source

Breast cancer-associated paraneoplastic neuromyelitis optica with cervical cord compression and spondylosis requiring laminectomy: A case report

SAGE Open Medical Case Reports, 2023
Neuromyelitis optica, an autoimmune inflammatory disorder affecting the central nervous system, can occur in a paraneoplastic context, although rare.
Bahadar S Srichawla, Shravan Sivakumar, Seyedeh N Cheraghi, Vincent Kipkorir, Maria A Garcia-Dominguez   +4 more
doaj   +1 more source

Clinical features, gender differences, disease course, and outcome in neuromyelitis optica spectrum disorder

Annals of Indian Academy of Neurology, 2021
Introduction: Neuromyelitis optica spectrum disorder (NMOSD) is an astrocytopathy with a predilection for the optic nerve, spinal cord, and brainstem. In this ambispective study, we evaluate clinical characteristics, responses to therapy, and disability ...
Nishita Singh, Rohit Bhatia, Prerna Bali, V Sreenivas, M V Padma, Vinay Goyal, Rohit Saxena, Deepa Dash, Ajay Garg, S Leve Joseph   +9 more
doaj   +1 more source

Interferon-beta-related tumefactive brain lesion in a Caucasian patient with neuromyelitis optica and clinical stabilization with tocilizumab [PDF]

, 2014
Background: Neuromyelitis optica (NMO) is a severely disabling inflammatory disorder of the central nervous system and is often misdiagnosed as multiple sclerosis (MS).
Aktas, Orhan, Goebels, Norbert, Harmel, Jens, Hartung, Hans-Peter, Ingwersen, Jens, Jarius, Sven, Mathys, Christian, Ringelstein, Marius   +7 more
core   +1 more source

Movement Disorders in Neuromyelitis Optica Spectrum Disorder: A Systematic Review

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Several movement disorders (MD) have been reported to occur in neuromyelitis optica spectrum disorder (NMOSD). No extensive review has addressed the whole spectrum of MD in NMOSD. Objective This article aims to review MD in NMOSD, describing its prevalence and features.
Luciana A.F. Bringel, Pedro L.G.S.B. Lima, Pedro V.F. Rodrigues, Francisco L.H.B. Cavalcante, Amanda R. Pinheiro, Fabricia M.S. Saraiva, Cynthia P. Rodrigues, Paulo V.S. Gonçalves, Leonardo J.R.A. Melo, Antônio E. Camelo‐Filho, Avelino M. Dutra‐Junior, Samuel R.O. Veras, Fernanda M.M. Carvalho, Flávia P.S. Rolim, Gabriela J. Martins, José A.C. D'Almeida, Pedro Braga‐Neto, Milena S. Pitombeira, Paulo R. Nobrega   +18 more
wiley   +1 more source

Fatal anti-aquaporin-4 seropositive neuromyelitis optica spectrum disorder in tuberculosis [PDF]

, 2014
© 2014 Sridhar et al.; licensee BioMed Central Ltd.Background: Neuromyelitis optica (NMO) is an autoimmune inflammatory condition of the central nervous system that is characterized by circulating anti-aquaporin-4 antibodies, transverse myelitis and ...
Chan, JFW, Sridhar, S, Yuen, KY
core   +1 more source

Letter on “Real‐World Clinical Experience With Serum MOG and AQP4 Antibody Testing by Live Versus Fixed Cell‐Based Assay”

Annals of Clinical and Translational Neurology, EarlyView.
Raveena Vij, Alexander J. Jonokuchi, Ilya Kister   +2 more
wiley   +1 more source