Results 101 to 110 of about 12,119 (223)

Posterior Spinal Artery Infarction With Unilateral Lumbar Spinal Cord Lesion: A Challenge in Early Diagnosis

Journal of General and Family Medicine, Volume 27, Issue 3, May 2026.
ABSTRACT A 71‐year‐old woman presented with acute muscle weakness and paresthesia in her left lower limb with the preceding back pain and impaired deep sensation. Although initial brain and spinal MRI were normal, follow‐up spinal MRI confirmed the left‐sided posterior lesion at T10 to T12 vertebral level, leading to the diagnosis of posterior spinal ...
Munenori Iwamoto, Aoi Fukunaga, Toshiyuki Uehara   +2 more
wiley   +1 more source

New onset neuromyelitis optica in a young Nigerian woman with possible antiphospholipid syndrome: a case report [PDF]

, 2008
Introduction Devic's neuromyelitis optica is an inflammatory demyelinating disease that targets the optic nerves and spinal cord. It has a worldwide distribution and distinctive features that distinguish it from multiple sclerosis.
Morenikeji A. Komolafe, Edward O. Komolafe, Taofiki A. Sunmonu, S. O. Olateju, C. M. Asaleye, Olufemi A. Adesina, S. A. Badmus, DM Wingerchuk, DM Wingerchuk, DM Wingerchuk, A Jacob, BG Weinshenker, M Matiello, BO Osuntokun, E Vasonnenberg, RN Mandler, F Tezzon, C Jacobi   +17 more
core   +1 more source

Relapse and Neurological Prognosis in Myelin Oligodendrocyte Glycoprotein Antibody‐Associated Disease: A Retrospective Secondary Analysis of a Japanese Nationwide Epidemiologic Survey

Clinical and Experimental Neuroimmunology, Volume 17, Issue 2, May 2026.
ABSTRACT Background Some patients with myelin oligodendrocyte glycoprotein antibody‐associated disease (MOGAD) experience multiple relapses and poor prognoses; however, the factors associated with these outcomes are unclear. This study aimed to identify factors associated with relapse and neurological prognosis in patients with MOGAD.
Masashi Nakamura, Juichi Fujimori, Akiyuki Uzawa, Satoshi Kuwabara, Ichiro Nakashima   +4 more
wiley   +1 more source

Recurrent longitudinally extensive transversal myelitis in a patient with Sjögren’s syndrome [PDF]

, 2013
Introduction. Longitudinally extensive transverse myelitis (LETM) is a transversal myelitis that extends through three or more vertebral segments in length. Case report.
Gvozdenović Slobodan, Jovin Zita, Kokai-Zekić Timea, Lučić-Prokin Aleksandra, Petrović Kosta, Turkalj Ivan, Šekarić Jelena, Živanović Željko   +7 more
core   +1 more source

Cases of AQP4‐Antibody‐Positive Neuromyelitis Optica Spectrum Disorder Successfully Discontinuing Steroids With Satralizumab Treatment: Considerations on the Method of Tapering for Steroids After the Introduction of Satralizumab

Clinical and Experimental Neuroimmunology, Volume 17, Issue 2, May 2026.
ABSTRACT Background Satralizumab is used for the treatment of neuromyelitis optica spectrum disorder (NMOSD). However, there are currently no standardized guidelines regarding the method or speed of steroid tapering after its introduction. In 2023, we proposed a method to commence tapering prednisolone at a rate of 1 mg every 4 weeks, starting 8 weeks ...
Kiyotaka Nakamagoe, Mayuko Tanaka, Kota Igari, Tetsu Suzuki, Shinji Saiki   +4 more
wiley   +1 more source

MOG-IgG in primary and secondary chronic progressive multiple sclerosis: a multicenter study of 200 patients and review of the literature [PDF]

, 2018
Background: Antibodies to human full-length myelin oligodendrocyte glycoprotein (MOG-IgG) as detected by new-generation cell-based assays have recently been described in patients presenting with acute demyelinating disease of the central nervous system ...
Abdelhak, A., Ayzenberg, I., Fechner, K., Grüter, T., Haas, J., Huss, A., Jarius, S., Kleiter, I., Leypoldt, F., Paul, F., Pawlitzki, M., Reindl, M., Ruprecht, K., Stellmann, J. P., Trebst, C., Tumani, H., Wildemann, B., Willing, A.   +17 more
core   +2 more sources

Cerebrospinal Fluid sCD27 as a Biomarker of Neuroinflammatory Disease: A Systematic Review and Meta‐Analysis

Journal of Neurochemistry, Volume 170, Issue 5, May 2026.
Neuroinflammatory diseases of the CNS are difficult to diagnose, and current CSF biomarkers lack sensitivity across conditions. Soluble CD27 (sCD27), a marker of adaptive immune activation, has emerged as a promising candidate, but its clinical utility remains uncertain.
Nadia Damholt Savino, Malene Bredahl Hansen, Amanda Marie Lund Christiansen, Sahla El Mahdaoui, Finn Sellebjerg, Jeppe Romme Christensen   +5 more
wiley   +1 more source

Role of Glutamatergic Excitotoxicity in Neuromyelitis Optica Spectrum Disorders

Frontiers in Cellular Neuroscience, 2019
Neuromyelitis optica spectrum disorder (NMOSD) is an inflammatory disorder mediated by immune-humoral responses directed against central nervous system (CNS) antigens.
Ana Paula Bornes da Silva, Ana Paula Bornes da Silva, Débora Guerini Souza, Diogo Onofre Souza, Denise Cantarelli Machado, Denise Cantarelli Machado, Douglas Kazutoshi Sato   +6 more
doaj   +1 more source

Aquaporin modulators: a patent review (2010-2015) [PDF]

, 2016
Introduction: Since the discovery of aquaporin-1 (AQP1) as a water channel, more than 2,000 articles, reviews and chapters have been published.
Casini, Angela, Soveral, Graça
core   +1 more source

Multicentre comparison of a diagnostic assay: Aquaporin-4 antibodies in neuromyelitis optica [PDF]

, 2016
Objective Antibodies to cell surface central nervous system proteins help to diagnose conditions which often respond to immunotherapies. The assessment of antibody assays needs to reflect their clinical utility.
Aktas, O. (Orhan), Altintas, A. (Ayse), Barington, T. (Torben), Berki, T. (Tímea), Berthele, A. (Achim), Bertolotto, A. (Antonio), Comabella, M. (Manuel), Costa, C. (Carme), Deniz, G. (Gunnur), Giometto, B., Granieri, L., Hamann, D. (Dörte), Hartung, H.P., Hintzen, R.Q. (Rogier), Höftberger, R. (Romana), Illes, Z. (Zsolt), Jarius, S. (Sven), Kral, V. (Vlastimil), Leite, M.I. (M. Isabel), Lillevang, S.T. (Søren T.), Marignier, R. (Romain), Montalban, X. (Xavier), Nielsen, H.H. (Helle Hvilsted), Nytrova, P. (Petra), Palace, J. (Jacqueline), Paul, F. (Friedemann), Pelt - Gravesteijn, E.D. (Daniëlle) van, Probst, M. (Monika), Reindl, M. (Markus), Rentzsch, K. (Kristin), Ruiz, A. (Anne), Saiz, A. (Albert Abe), Saschenbrecker, S. (Sandra), Schanda, K. (Kathrin), Siva, A. (Aksel), Sobek, O. (Ondrej), Tintoré, M., Trillenberg, P. (Peter), Tuller, F. (Friederike), Vedeler, C. (Christian), Vincent, A.J.P.E. (Arnoud), Waters, P. (Patrick), Wildemann, B. (Brigitte), Woodhall, M. (Mark), Zuliani, L. (Luigi)   +44 more
core   +1 more source