Results 21 to 30 of about 9,342,488 (306)

Technical performance and diagnostic utility of the new Elecsys (R) neuron-specific enolase enzyme immunoassay [PDF]

, 2003
This international multicenter study was designed to evaluate the technical performance of the new double-monoclonal, single-step Elecsys neuron-specific enolase (NSE) enzyme immunoassay (EIA) and to assess its utility as a sensitive and specific test ...
Pawel, Joachim von, von Pawel, J., Gurr, E., Stieber, P., Roth, Hans-Jürgen, Fürst, Heinrich, Ebert, W., Raith, Hannelore, Muley, T., Nagel, D., Muley, Thomas, Uhl, Wolfgang, Nagel, Dorothea, Drings, Peter, Holdenrieder, Stefan, Drings, P., Raith, H., Blijenberg, Bert G., Ebert, Werner, Stieber, Petra, Luthe, Hilmar, Uhl, W., Roth, H. J., Blijenberg, B. G., Gurr, Eberhard, Holdenrieder, S.   +25 more
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Spinal muscular atrophy patient iPSC-derived motor neurons have reduced expression of proteins important in neuronal development [PDF]

, 2016
This work was supported by The RJAH Institute of Orthopaedics, UK (H.F.), The SMA Trust, UK (H.F.), Cedars-Sinai Institutional startup funds (D.S), California Institute for Regenerative Medicine Grant RT-02040 (D.S.), National Center for Advancing ...
Heidi R. Fuller, Andrew R. Gross, Kaus, Anjoscha, Morris, Glen, Sareen, Dhruv, Glenn E. Morris, Fuller, H, Shirran, Sally Lorna, Catherine H. Botting, Shirran, SL, Botting, Catherine Helen, Dhruv Sareen, Mandefro, Berhan, Botting, CH, Gross, AR, Berhan Mandefro, Fuller, Heidi, Sally L. Shirran, Sareen, S, Morris, GE, Anjoscha S. Kaus, Gross, Andrew, Mandefro, B, Kaus, AS, Andrew R Gross, Heidi R Fuller, Catherine H Botting, Berhan eMandefro, Sally L Shirran, Anjoscha Samija Kaus, Fuller, HR, Dhruv eSareen, Glenn E Morris, Shirran, Sally Lorna; id_orcid   +33 more
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Neuron-Specific Conditional Expression of a Mitochondrially Targeted Fluorescent Protein in Mice [PDF]

The Journal of Neuroscience, 2006
Mitochondrial dysfunction contributes to the pathophysiology of both acute and chronic neurodegenerative disorders. Quantification of mitochondrial bioenergetic properties generally requires the use of isolated brain mitochondria. However, the involvement of neuronal mitochondrial dysfunction in these disorders is limited by the lack of markers, and ...
Krish, Chandrasekaran, Julie L, Hazelton, Yu, Wang, Gary, Fiskum, Tibor, Kristian   +4 more
openaire   +2 more sources

Transmembrane Batten Disease Proteins Interact With a Shared Network of Vesicle Sorting Proteins, Impacting Their Synaptic Enrichment

Frontiers in Neuroscience, 2022
Batten disease is unique among lysosomal storage disorders for the early and profound manifestation in the central nervous system, but little is known regarding potential neuron-specific roles for the disease-associated proteins.
Mitchell J. Rechtzigel, Brandon L. Meyerink, Brandon L. Meyerink, Hannah Leppert, Tyler B. Johnson, Jacob T. Cain, Gavin Ferrandino, Danielle G. May, Kyle J. Roux, Kyle J. Roux, Jon J. Brudvig, Jon J. Brudvig, Jill M. Weimer, Jill M. Weimer   +13 more
doaj   +1 more source

Specific neuron model parameters.

, 2021
Specific neuron model parameters.
Eduarda Susin (11442545), Alain Destexhe (259217)   +1 more
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Immunohistochemistry of neuron-specific and glia-specific proteins.

Archives of Histology and Cytology, 1989
This paper reviews the immunohistochemical distribution of four brain-derived proteins, NSE, NFP, spot 35 and S-100 protein, in neuronal and paraneuronal tissues, concentrating on the results of our own research group. Neuron-specific enolase (NSE), a brain-specific isozyme of the glycolytic enzyme enolase, is characterized by its consistent occurrence
IWANAGA, Toshihiko, TAKAHASHI, Yasuo, FUJITA, Tsuneo   +2 more
openaire   +3 more sources

ASSESSMENT OF THE NEURONAL DAMAGE AND OXIDATIVE STRESS MARKERS LEVEL IN POST STROKE PATIENTS

Медична наука України, 2019
Relevance. 100-110 000 acute disorders of cerebral circulation are registered in Ukraine annually, about 57% of which are ischemic stroke (IS). Study of dynamics of the neuronal damage markers level and their correlation with oxidative stress indicators ...
V.R. Gerasymchuk
doaj   +1 more source

Single-cell expression predicts neuron-specific protein homeostasis networks

Open Biology, 2023
Abstract The protein homeostasis network keeps proteins in their correct shapes and avoids unwanted aggregation. In turn, the accumulation of aberrantly misfolded proteins has been directly associated with the onset of ageing-associated neurodegenerative diseases such as Alzheimer's and Parkinson's.
openaire   +3 more sources

FUS-SMN Protein Interactions Link the Motor Neuron Diseases ALS and SMA [PDF]

, 2012
Mutations in the RNA binding protein FUS cause amyotrophic lateral sclerosis (ALS), a fatal adult motor neuron disease. Decreased expression of SMN causes the fatal childhood motor neuron disorder spinal muscular atrophy (SMA).
Das, Rita, Maniatis, Tom, Sharma, A, Yan, Biao, Tapia, JC, Gygi, Steve P., Monica A. Carrasco, Shneider, NA, Nishimura, AL, Chen, Shi, Yu, Yong, Sharma, Aarti, Yan, B, Gygi, SP, Christopher E. Shaw, Yamazaki, T, Steve P. Gygi, Siddharthan Chandran, Reed, Robin, Yu, Y, Aarti Sharma, Reed, R, Yong Yu, Rita Das, Das, R, Carrasco, Monica A., Zhai, Bo, Shneider, Neil A., Chen, S, Juan C. Tapia, Tapia, Juan C., Agnes Lumi Nishimura, Lalancette-Hebert, Melanie, Haertlein, TC, Tom Maniatis, Lalancette-Hebert, M, Biao Yan, Carrasco, MA, Neil A. Shneider, Yamazaki, Tomohiro, Nishimura, Agnes Lumi, Sullivan, G, Maniatis, T, Shaw, Christopher E., Shi Chen, Zhai, B, Melanie Lalancette-Hebert, Sullivan, Gareth, Tyler C. Haertlein, Shaw, CE, Chandran, S, Haertlein, Tyler C., Tomohiro Yamazaki, Gareth Sullivan, Robin Reed, Bo Zhai, Chandran, Siddharthan, Sullivan, Gareth; id_orcid   +57 more
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Neuron-specific Edis depletion leads to hyperactivation of innate immunity.

, 2022
The UAS-shEdis or control UAS-shGFP flies were crossed to the neuron-specific Elav-Gal4 driver line. Levels of the circRNA Edis or the Dpt mRNA in male or female fly head samples were measured (student t test, n = 3, * ppp (TIF)
Shiyu Xu (9662931), Jian-Liang Li (561531), Ranjan J. Perera (7331489), Xiao-Peng Xiong (680426), Weihong Liang (431780), Antonio Tito (14019308), Sheng Zhang (111330), Julia Situ (12328637), Rui Zhou (38109), Wei Liu (20030), Daniel Martinez (70122), Chunlai Wu (35481)   +11 more
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