Results 11 to 20 of about 1,209,467 (344)
Frontiers in Neuroinformatics, 2009 The NEURON simulation program now allows Python to be used, alone or in combination with NEURON's traditional Hoc interpreter. Adding Python to NEURON has the immediate benefit of making available a very extensive suite of analysis tools written for engineering and science.
Hines, Michael L +2 more
openaire +4 more sources
Frontiers in Psychology, 2021 Creativity generates novel solutions to tasks by processing information. Imagination and mental representations are part of the creative process; we can mull over ideas of our own making, and construct algorithms or scenarios from them. Social scenario-building can be viewed as a human cognitive “super-power” that involves abstraction, meta ...
openaire +4 more sources
Converging Mechanisms of p53 Activation Drive Motor Neuron Degeneration in Spinal Muscular Atrophy
Cell Reports, 2017 The hallmark of spinal muscular atrophy (SMA), an inherited disease caused by ubiquitous deficiency in the SMN protein, is the selective degeneration of subsets of spinal motor neurons.
Christian M. Simon +10 more
doaj +1 more source
Nature Communications, 2022 Here, authors show that Smad3 acetylation via HDAC6 inhibition reverses Duchenne muscular dystrophy-like symptoms in the mdx mouse model, suggesting a potential therapeutic target for the disorder.
Alexis Osseni +10 more
doaj +1 more source
Molecular Brain, 2017 The tree shrew, as a primate-like animal model, has been used for studying high brain functions such as social emotion and spatial learning memory. However, little is known about the excitatory synaptic transmission in cortical brain areas of the tree ...
Xu-Hui Li +5 more
doaj +1 more source
Molecular Brain, 2020 An amendment to this paper has been published and can be accessed via the original article.
Kohei Koga +10 more
doaj +1 more source
Defective axonal transport in motor neuron disease [PDF]
, 2007 Several recent studies have highlighted the role of axonal transport in the pathogenesis of motor neuron diseases. Mutations in genes that control microtubule regulation and dynamics have been shown to cause motor neuron degeneration in mice and in a ...
Baas +77 more
core +1 more source
Nature Communications, 2023 Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease characterized by progressive motor neuron loss, with additional pathophysiological involvement of non-neuronal cells such as microglia.
Björn F. Vahsen +18 more
doaj +1 more source
Timing Control of Single Neuron Spikes with Optogenetic Stimulation [PDF]
, 2018 This paper predicts the ability to externally control the firing times of a cortical neuron whose behavior follows the Izhikevich neuron model. The Izhikevich neuron model provides an efficient and biologically plausible method to track a cortical neuron'
Eckford, Andrew W. +3 more
core +2 more sources
Microvascular decompression for hemifacial spasm: a review of twenty-one operated cases
The Egyptian Journal of Neurology, Psychiatry and Neurosurgery, 2020 Background Microvascular decompression of facial nerve provides definitive and long-term cure for hemifacial spasm. We review our experience of treating hemifacial spasm by microvascular decompression.
Amey P. Patankar
doaj +1 more source