Results 41 to 50 of about 465,559 (289)

Involvement of the Acyl-CoA binding domain containing 7 in the control of food intake and energy expenditure in mice

eLife, 2016
Acyl-CoA binding domain-containing 7 (Acbd7) is a paralog gene of the diazepam-binding inhibitor/Acyl-CoA binding protein in which single nucleotide polymorphism has recently been associated with obesity in humans.
Damien Lanfray, Alexandre Caron, Marie-Claude Roy, Mathieu Laplante, Fabrice Morin, Jérôme Leprince, Marie-Christine Tonon, Denis Richard   +7 more
doaj   +1 more source

Upregulation of Apol8 by Epothilone D facilitates the neuronal relay of transplanted NSCs in spinal cord injury

Stem Cell Research & Therapy, 2021
Background Microtubule-stabilizing agents have been demonstrated to modulate axonal sprouting during neuronal disease. One such agent, Epothilone D, has been used to treat spinal cord injury (SCI) by promoting axonal sprouting at the lesion site after ...
Weiwei Xue, Haipeng Zhang, Yongheng Fan, Zhifeng Xiao, Yannan Zhao, Weiyuan Liu, Bai Xu, Yanyun Yin, Bing Chen, Jiayin Li, Yi Cui, Ya Shi, Jianwu Dai   +12 more
doaj   +1 more source

Co-transplantation of Human Embryonic Stem Cell-derived Neural Progenitors and Schwann Cells in a Rat Spinal Cord Contusion Injury Model Elicits a Distinct Neurogenesis and Functional Recovery [PDF]

Co-transplantation of neural progenitors (NPs) with Schwann cells (SCs) might be a way to overcome low rate of neuronal differentiation of NPs following transplantation in spinal cord injury (SCI) and the improvement of locomotor recovery. In this study,
Ali Niapour, Ao Q., Baharvand H., Basso D. M., Beattie M. S., Ben-Hur T., Biernaskie J., Blakemore W. F., Bradbury E. J., Brierley C. M., Bruce J. H., Calella A. M., Cao Q. L., Cao Q. L., Castellanos D. A., Cho S. R., Cohen M. A., Cui L., Cummings B. J., Daadi M. M., David S., Deng Y. B., Deshpande D. M., Dhara S. K., Ernsberger U., Fereshteh Karamali, Fouad K., Gage F. H., Golden K. L., Gruner J. A., Haruta M., Hatami M., Hill C. E., Hofstetter C. P., Hong S., Hossein Baharvand, Islam O., Iwanami A., Joannides A. J., Joannides A. J., Kamada T., Kamei N., Karimi-Abdolrezaee S., Kerr D. A., Keyvan-Fouladi N., Kimura H., Koch P., Kumagai G., Li J., Lim M. S., Lindvall O., Livak K. J., Lu P., Lund R. D., Madhavan L., McDonald J. W., Menei P., Meng X. T., Mohammad Hossein Nasr-Esfahani, Mohammad Mardani, Mollamohammadi S., Murray M., Nemati S., Niapour A., Okada S., Olson H. E., Pal R., Papastefanaki F., Parati E. A., Park D. H., Parr A. M., Pearse D. D., Pearse D. D., Pfeifer K., Pincus D. W., Ramer L. M., Roy N. S., Salehi M., Sasaki M., Shin S., Shiva Nemati, Smith R., Takami T., Tetzlaff W., Thuret S., Tobias C. A., Tsuji O., Vargas M. E., Wang G., Webber D. J., Widenfalk J., Willerth S. M., Yan J., Yan J., Zahra Taghipour, Zeng Y. S., Zhang X., Zhang Y. Q.   +97 more
core   +2 more sources

Atg5 and Ambra1 differentially modulate neurogenesis in neural stem cells [PDF]

, 2012
Neuroepithelial cells undergoing differentiation efficiently remodel their cytoskeleton and shape in an energy-consuming process. The capacity of autophagy to recycle cellular components and provide energy could fulfill these requirements, thus ...
Arroba, A, Boya, P, Cecconi, F, De La Rosa, E, De Pablo, F, Vázquez, P   +5 more
core   +2 more sources

Spatiomechanical Modulation of EphB4-Ephrin-B2 Signaling in Neural Stem Cell Differentiation. [PDF]

, 2018
Interactions between EphB4 receptor tyrosine kinases and their membrane-bound ephrin-B2 ligands on apposed cells play a regulatory role in neural stem cell differentiation.
Chung, Jean, Dong, Meimei, Groves, Jay, Lee, Young, SCHAFFER, David, Spelke, Dawn, Yu, Cheng-Han   +6 more
core   +2 more sources

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Non-catalytic roles for TET1 protein negatively regulating neuronal differentiation through srGAP3 in neuroblastoma cells

Protein & Cell, 2016
The methylcytosine dioxygenases TET proteins (TET1, TET2, and TET3) play important regulatory roles in neural function. In this study, we investigated the role of TET proteins in neuronal differentiation using Neuro2a cells as a model.
Jie Gao, Yue Ma, Hua-Lin Fu, Qian Luo, Zhen Wang, Yu-Huan Xiao, Hao Yang, Da-Xiang Cui, Wei-Lin Jin   +8 more
doaj   +1 more source

Caveolin-1 plays a crucial role in inhibiting neuronal differentiation of neural stem/progenitor cells via VEGF signaling-dependent pathway. [PDF]

PLoS ONE, 2011
In the present study, we aim to elucidate the roles of caveolin-1(Cav-1), a 22 kDa protein in plasma membrane invaginations, in modulating neuronal differentiation of neural progenitor cells (NPCs).
Yue Li, Jianmin Luo, Wui-Man Lau, Guoqing Zheng, Shuping Fu, Ting-Ting Wang, He-Ping Zeng, Kwok-Fai So, Sookja Kim Chung, Yao Tong, Kejian Liu, Jiangang Shen   +11 more
doaj   +1 more source

Caveolin-1 Phosphorylation Is Essential for Axonal Growth of Human Neurons Derived From iPSCs. [PDF]

, 2019
Proper axonal growth and guidance is essential for neuron differentiation and development. Abnormal neuronal development due to genetic or epigenetic influences can contribute to neurological and mental disorders such as Down syndrome, Rett syndrome, and
Almenar-Queralt, Angels, DerMardirossian, Celine, Head, Brian P, Leem, Joseph, Patel, Hemal H, Patel, Piyush M, Roth, David M, Wang, Shanshan, Zhang, Zheng   +8 more
core   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source