Results 21 to 30 of about 1,427,821 (305)
Transmitochondrial embryonic stem cells containing pathogenic mtDNA mutations are compromised in neuronal differentiation [PDF]
, 2009 Objectives: Defects of the mitochondrial genome (mtDNA) cause a series of rare, mainly neurological disorders. In addition, they have been implicated in more common forms of movement disorders, dementia and the ageing process.
Smulders-Srinivasan, T. K. +18 more
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The neuropeptide 26RFa in the human gut and pancreas: potential involvement in glucose homeostasis
Endocrine Connections, 2019 Objective: Recent studies performed in mice revealed that the neuropeptide 26RFa regulates glucose homeostasis by acting as an incretin and by increasing insulin sensitivity.
Gaëtan Prévost +14 more
doaj +1 more source
Neuronal differentiation by analogs of staurosporine [PDF]
Neurochemistry International, 2010 RGC-5 cells are transformed cells that express several surface markers characteristic of neuronal precursor cells, but resemble glial cells morphologically and divide in culture. When treated with the apoptosis-inducing agent staurosporine, RGC-5 cells assume a neuronal morphology, extend neurites, stop dividing, and express ion channels without acute ...
Alex F, Thompson, Leonard A, Levin
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Frontiers in Endocrinology, 2018 The European eel (Anguilla anguilla) presents a blockade of sexual maturation at a prepubertal stage due to a deficient production of gonadotropins.
Jérémy Pasquier +10 more
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Frontiers in Cellular Neuroscience, 2020 Cognitive impairment is one of the major symptoms in most neurodegenerative disorders such as Alzheimer’s (AD), Parkinson (PD), and Huntington diseases (HD), affecting millions of people worldwide.
Irene Solés-Tarrés +3 more
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Strategies for the Identification of Bioactive Neuropeptides in Vertebrates
Frontiers in Neuroscience, 2019 Neuropeptides exert essential functions in animal physiology by controlling e.g., reproduction, development, growth, energy homeostasis, cardiovascular activity and stress response.
Auriane Corbière +10 more
doaj +1 more source
Biology, 2021 Human adipose-derived mesenchymal stem cells (hASCs) may be used in some nervous system pathologies, although obtaining an adequate degree of neuronal differentiation is an important barrier to their applicability.
Rosa Hernández +9 more
doaj +1 more source
Neuronal differentiation and neurodegeneration: the role of Nogo-A? [PDF]
, 2022 Parkinson’s disease (PD) is one of the most common neurodegenerative diseases. One of the main characteristics of this disorder is the degenerative loss of midbrain dopaminergic (DAergic) neurons of the substantia nigra pars compacta (SNpc ...
Lanci, Luigina
core
Life, 2023 Phytocannabinoids, with their variety of beneficial effects, represent a valid group of substances that could be employed as neurogenesis-enhancers or neuronal differentiation inducers.
Andrea Valeri +5 more
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Reducing the Mystery of Neuronal Differentiation [PDF]
Cell, 2009 In the developing nervous system, neural progenitors exit the cell cycle and differentiate on a precise schedule, yet the mechanisms driving this process remain poorly defined. Yan et al. (2009) now identify a thiol-redox reaction mediated by the membrane protein GDE2 and the peroxiredoxin protein Prdx1 that promotes neurogenesis.
Novitch, Bennett G., Butler, Samantha J.
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