Results 1 to 10 of about 277,318 (263)
Bag1 is a regulator and marker of neuronal differentiation [PDF]
Cell Death & Differentiation, 2002 Bag 1 acts as a co-chaperone for Hsp70/Hsc70. We report here that stable over-expression of Bag1 in immortalized neuronal CSM14.1 cells prevents death following serum deprivation. Bag1 over-expression slowed the proliferative rate of CSM14.1 cells, resulted in increased levels of phospo-MAP kinases and accelerated neuronal differentiation ...
P, Kermer +6 more
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Extracellular matrix and biomimetic engineering microenvironment for neuronal differentiation
Neural Regeneration Research, 2020 Extracellular matrix (ECM) influences cell differentiation through its structural and biochemical properties. In nervous system, neuronal behavior is influenced by these ECMs structures which are present in a meshwork, fibrous, or tubular forms ...
Deepak Jain +3 more
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Epilepsy-Induced Motility of Differentiated Neurons [PDF]
Cerebral Cortex, 2013 Neuronal ectopia, such as granule cell dispersion (GCD) in temporal lobe epilepsy (TLE), has been assumed to result from a migration defect during development. Indeed, recent studies reported that aberrant migration of neonatal-generated dentate granule cells (GCs) increased the risk to develop epilepsy later in life.
Chai, Xuejun +8 more
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Improvement of neuronal differentiation by carbon monoxide: Role of pentose phosphate pathway
Redox Biology, 2018 Over the last decades, the silent-killer carbon monoxide (CO) has been shown to also be an endogenous cytoprotective molecule able to inhibit cell death and modulate mitochondrial metabolism.
Ana S. Almeida +5 more
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Stem Cell Research & Therapy, 2020 Introduction Stem cell transplantation of exogenous neural progenitor cells (NPCs) derived from mesenchymal stem cells (MSCs) has emerged as a promising approach for neurodegenerative disease.
Anupong Songsaad +4 more
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FOXP2 drives neuronal differentiation by interacting with retinoic acid signaling pathways
Frontiers in Cellular Neuroscience, 2014 FOXP2 was the first gene shown to cause a Mendelian form of speech and language disorder. Although developmentally expressed in many organs, loss of a single copy of FOXP2 leads to a phenotype that is largely restricted to orofacial impairment during ...
Paolo eDevanna +3 more
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Nature CommunicationsNeuronal differentiation—the development of neurons from neural stem cells—involves neurite outgrowth and is a key process during the development and regeneration of neural functions.
Shunsuke Chuma +8 more
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The Dietary Flavonoid, Luteolin, Negatively Affects Neuronal Differentiation
Frontiers in Molecular Neuroscience, 2019 Luteolin, a polyphenolic plant flavonoid, has been attributed with numerous beneficial properties like anti-cancer, antioxidant, and anti-inflammatory action.
Amrutha Swaminathan +7 more
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A method for siRNA-mediated knockdown of target genes in RA-induced neurogenesis using P19 cells
MethodsXThis study presents a comprehensive protocol for siRNA-mediated knockdown in the differentiation of P19 cells into neuronal-like cells. Utilizing a retinoic acid (RA)-induced neurogenesis model, P19 cells were cultured under specific conditions that ...
Hossein Khodadadi, Hiroaki Taniguchi
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Stem Cells International, 2012 Efficient in vitro differentiation into specific cell types is more important than ever after the breakthrough in nuclear reprogramming of somatic cells and its potential for disease modeling and drug screening.
Sally K. Mak +7 more
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