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Effects of silica nanoparticle exposure on mitochondrial function during neuronal differentiation [PDF]
Background Nanomedicine offers a promising tool for therapies of brain diseases, but potential effects on neuronal health and neuronal differentiation need to be investigated to assess potential risks.
Angélique D. Ducray +7 more
doaj +2 more sources
Editorial: New Microenvironments for Neuronal Differentiation
Editorial of a Research ...
Lecchi, Marzia, Gelain, Fabrizio
openaire +4 more sources
Epilepsy-Induced Motility of Differentiated Neurons [PDF]
Neuronal ectopia, such as granule cell dispersion (GCD) in temporal lobe epilepsy (TLE), has been assumed to result from a migration defect during development. Indeed, recent studies reported that aberrant migration of neonatal-generated dentate granule cells (GCs) increased the risk to develop epilepsy later in life.
Chai, Xuejun +8 more
openaire +3 more sources
Retinoic acid signaling and neuronal differentiation [PDF]
The identification of neurological symptoms caused by vitamin A deficiency pointed to a critical, early developmental role of vitamin A and its metabolite, retinoic acid (RA). The ability of RA to induce post-mitotic, neural phenotypes in various stem cells, in vitro, served as early evidence that RA is involved in the switch between proliferation and ...
Janesick, Amanda +2 more
openaire +5 more sources
Extracellular matrix and biomimetic engineering microenvironment for neuronal differentiation
Extracellular matrix (ECM) influences cell differentiation through its structural and biochemical properties. In nervous system, neuronal behavior is influenced by these ECMs structures which are present in a meshwork, fibrous, or tubular forms ...
Deepak Jain +3 more
doaj +1 more source
Improvement of neuronal differentiation by carbon monoxide: Role of pentose phosphate pathway
Over the last decades, the silent-killer carbon monoxide (CO) has been shown to also be an endogenous cytoprotective molecule able to inhibit cell death and modulate mitochondrial metabolism.
Ana S. Almeida +5 more
doaj +1 more source
FOXP2 drives neuronal differentiation by interacting with retinoic acid signaling pathways
FOXP2 was the first gene shown to cause a Mendelian form of speech and language disorder. Although developmentally expressed in many organs, loss of a single copy of FOXP2 leads to a phenotype that is largely restricted to orofacial impairment during ...
Paolo eDevanna +3 more
doaj +1 more source
The Dietary Flavonoid, Luteolin, Negatively Affects Neuronal Differentiation
Luteolin, a polyphenolic plant flavonoid, has been attributed with numerous beneficial properties like anti-cancer, antioxidant, and anti-inflammatory action.
Amrutha Swaminathan +7 more
doaj +1 more source
Neuronal differentiation—the development of neurons from neural stem cells—involves neurite outgrowth and is a key process during the development and regeneration of neural functions.
Shunsuke Chuma +8 more
doaj +1 more source
Introduction Stem cell transplantation of exogenous neural progenitor cells (NPCs) derived from mesenchymal stem cells (MSCs) has emerged as a promising approach for neurodegenerative disease.
Anupong Songsaad +4 more
doaj +1 more source

