Results 11 to 20 of about 1,427,821 (305)

Effects of silica nanoparticle exposure on mitochondrial function during neuronal differentiation [PDF]

Journal of Nanobiotechnology, 2017
Background Nanomedicine offers a promising tool for therapies of brain diseases, but potential effects on neuronal health and neuronal differentiation need to be investigated to assess potential risks.
Angélique D. Ducray, Andrea Felser, Jana Zielinski, Aniela Bittner, Julia V. Bürgi, Jean-Marc Nuoffer, Martin Frenz, Meike Mevissen   +7 more
doaj   +3 more sources

Chronic treatment with the GLP1 analogue liraglutide increases cell proliferation and differentiation into neurons in an AD mouse model [PDF]

, 2013
Neurogenesis is a life long process, but the rate of cell proliferation and differentiation decreases with age. In Alzheimer's patients, along with age, the presence of Aβ in the brain inhibits this process by reducing stem cell proliferation and cell ...
Vadivel Parthsarathy, Hölscher, C., Parthsarathy, Vadivel, Parthsarathy, V., Holscher, Christian, Hölscher Christian, Christian Hölscher, Parthsarathy Vadivel   +7 more
core   +6 more sources

Cell-penetrating, antioxidant SELENOT mimetic protects dopaminergic neurons and ameliorates motor dysfunction in Parkinson's disease animal models

Redox Biology, 2021
Parkinson's disease (PD) is a neurodegenerative disorder characterized by motor dysfunction for which there is an unmet need for better treatment options.
Ifat Alsharif, Loubna Boukhzar, Benjamin Lefranc, David Godefroy, Juliette Aury-Landas, Jean-Luc do Rego, Jean-Claude do Rego, Frédéric Naudet, Arnaud Arabo, Abdeslam Chagraoui, David Maltête, Abdelhamid Benazzouz, Catherine Baugé, Jérôme Leprince, Abdel G. Elkahloun, Lee E. Eiden, Youssef Anouar   +16 more
doaj   +1 more source

Cytoplasmic long non-coding RNAs are differentially regulated and translated during human neuronal differentiation [PDF]

, 2021
The expression of long non-coding RNAs is highly enriched in the human nervous system. However, the function of neuronal lncRNAs in the cytoplasm and their potential translation remains poorly understood. Here we performed Poly-Ribo-Seq to understand the
BIRDS, ISABEL, CLAYTON, SOPHIE, Birds, I, BYFORD, ABIGAIL, Whitehouse, A, O'CONNELL, MARY J., Kosteletos, A, VASCONCELOS, ELTON J.R., Vasconcelos, EJR, WANG, DAPENG, Douka, K, Wang, D, ASPDEN, JULIE L., DEUCHARS, JIM, O'Connell, MJ, Deuchars, J, Clayton, S, WHITEHOUSE, ADRIAN, Byford, A, Aspden, JL, KOSTELETOS, ANDREAS, DOUKA, KATERINA   +21 more
core   +1 more source

Dopamine D3 Receptor: Contemporary Views of Its Function and Pharmacology for Neuropsychiatric Diseases

Biomolecules, 2021
Biomolecules has launched a Special Issue entitled “Dopamine D3 Receptor: Contemporary Views of Its Function and Pharmacology for Neuropsychiatric Diseases [...]
Philippe De Deurwaerdère, Abdeslam Chagraoui   +1 more
doaj   +1 more source

Melatonin: Facts, Extrapolations and Clinical Trials

Biomolecules, 2023
Melatonin is a fascinating molecule that has captured the imagination of many scientists since its discovery in 1958. In recent times, the focus has changed from investigating its natural role as a transducer of biological time for physiological systems ...
J. A. Boutin, D. J. Kennaway, R. Jockers
doaj   +1 more source

Reversion of neuronal differentiation induced in human adipose-derived stem cells

, 2022
Adipose-derived mesenchymal stem cells are a great alternative to other types of stem cells obtained from other tissues, since they are found in large numbers and are easy to obtain by liposuction and do not have ethical connotations.
Ortiz, Raul, Doello, Kevin, Prados, Jose, Mesas, Cristina, Hernandez, Rosa, Perazzoli, Gloria, Melguizo, Consolacion, Quinonero, Francisco   +7 more
core   +1 more source

Cytoprotective and Neurotrophic Effects of Octadecaneuropeptide (ODN) in in vitro and in vivo Models of Neurodegenerative Diseases

Frontiers in Endocrinology, 2020
Octadecaneuropeptide (ODN) and its precursor diazepam-binding inhibitor (DBI) are peptides belonging to the family of endozepines. Endozepines are exclusively produced by astroglial cells in the central nervous system of mammals, and their release is ...
Olfa Masmoudi-Kouki, Amira Namsi, Amira Namsi, Yosra Hamdi, Seyma Bahdoudi, Seyma Bahdoudi, Ikram Ghouili, Julien Chuquet, Jérôme Leprince, Jérôme Leprince, Benjamin Lefranc, Benjamin Lefranc, Taoufik Ghrairi, Marie-Christine Tonon, Gérard Lizard, David Vaudry, David Vaudry   +16 more
doaj   +1 more source

A two-step strategy for neuronal differentiation in vitro of human dental follicle cells [PDF]

, 2012
Human dental follicle cells (DFCs) derived from wisdom teeth are precursor cells for cementoblasts. In this study, we recognized that naive DFCs express constitutively the early neural cell marker b-IIItubulin.
Völlner, Florian
core   +1 more source

Characterization of the EM66 Biomarker in the Pituitary and Plasma of Healthy Subjects With Different Gonadotroph Status and Patients With Gonadotroph Tumor

Frontiers in Endocrinology, 2019
Granins and their derived-peptides are useful markers of secretion from normal and tumoral neuroendocrine cells. The need to identify new diagnostic markers for neuroendocrine tumors, including pituitary tumors prompted us to determine plasma levels of ...
Johann Guillemot, Marlène Guérin, Anne-Françoise Cailleux, Antoine-Guy Lopez, Jean-Marc Kuhn, Youssef Anouar, Laurent Yon   +6 more
doaj   +1 more source