Results 31 to 40 of about 470,748 (305)

Differentiation enhances Zika virus infection of neuronal brain cells. [PDF]

, 2018
Zika virus (ZIKV) is an emerging, mosquito-borne pathogen associated with a widespread 2015-2016 epidemic in the Western Hemisphere and a proven cause of microcephaly and other fetal brain defects in infants born to infected mothers. ZIKV infections have
Bouquet, Jerome, Chiu, Charles Y, Li, Tony, Paranjpe, Aditi, Streithorst, Jessica, Sánchez-San Martín, Claudia, Yu, Guixia   +6 more
core   +3 more sources

Local and global spontaneous calcium events regulate neurite outgrowth and onset of GABAergic phenotype during neural precursor differentiation [PDF]

, 2003
Neural stem cells can generate in vitro progenitors of the three main cell lineages found in the CNS. The signaling pathways underlying the acquisition of differentiated phenotypes in these cells are poorly understood.
Berridge, Michael J., Bootman, Martin D., Ciccolini, Francesca, Collins, Tony J., Lipp, Peter, Sudhoelter, Juliana   +5 more
core   +1 more source

Trimethylation and Acetylation of β-Catenin at Lysine 49 Represent Key Elements in ESC Pluripotency [PDF]

, 2017
Wnt/β-catenin signaling is required for embryonic stem cell (ESC) pluripotency by inducing mesodermal differentiation and inhibiting neuronal differentiation; however, how β-catenin counter-regulates these differentiation pathways is unknown.
Hoffmeyer, Katrin, Junghans, Dirk, Kanzler, Benoit, Kemler, Rolf   +3 more
core   +5 more sources

A dynamic and expandable digital 3D-atlas maker for monitoring the temporal changes in tissue growth during hindbrain morphogenesis

eLife, 2022
Reconstruction of prototypic three-dimensional (3D) atlases at the scale of whole tissues or organs requires specific methods to be developed. We have established a digital 3D-atlas maker (DAMAKER) and built a digital 3D-atlas to monitor the changes in ...
Matthias Blanc, Giovanni Dalmasso, Frederic Udina, Cristina Pujades   +3 more
doaj   +1 more source

Proteomic analyses reveal misregulation of LIN28 expression and delayed timing of glial differentiation in human iPS cells with MECP2 loss-of-function. [PDF]

, 2019
Rett syndrome (RTT) is a pervasive developmental disorder caused by mutations in MECP2. Complete loss of MECP2 function in males causes congenital encephalopathy, neurodevelopmental arrest, and early lethality.
Carromeu, Cassiano, Freitas, Beatriz CG, Ghosh, Anirvan, Hu, Xindao, Kim, Jean J, Lavallée-Adam, Mathieu, Miller, Meghan T, Muotri, Alysson R, Savas, Jeffrey N, Yates, John R   +9 more
core   +2 more sources

Multi-scale engineering for neuronal cell growth and differentiation [PDF]

, 2011
In this paper we investigate the role of micropatterning and molecular coating for cell culture and differentiation of neuronal cells (Neuro2a cell line) on a polydimethylsiloxane substrate.
Béduer, Amélie, Flahaut, Emmanuel, Loubinoux, Isabelle, Seichepine, Florent, Vaysse, Laurence, Vieu, Christophe   +5 more
core   +4 more sources

iASPP regulates neurite development by interacting with Spectrin proteins

Frontiers in Molecular Neuroscience, 2023
IntroductionSince its discovery in 1999, a substantial body of research has shown that iASPP is highly expressed in various kinds of tumors, interacts with p53, and promotes cancer cell survival by antagonizing the apoptotic activity of p53. However, its
Junhao Wang, Chunhong Jia, Qiong Gao, Jiwen Zhang, Xi Gu   +4 more
doaj   +1 more source

Co-transplantation of Human Embryonic Stem Cell-derived Neural Progenitors and Schwann Cells in a Rat Spinal Cord Contusion Injury Model Elicits a Distinct Neurogenesis and Functional Recovery [PDF]

Co-transplantation of neural progenitors (NPs) with Schwann cells (SCs) might be a way to overcome low rate of neuronal differentiation of NPs following transplantation in spinal cord injury (SCI) and the improvement of locomotor recovery. In this study,
Ali Niapour, Ao Q., Baharvand H., Basso D. M., Beattie M. S., Ben-Hur T., Biernaskie J., Blakemore W. F., Bradbury E. J., Brierley C. M., Bruce J. H., Calella A. M., Cao Q. L., Cao Q. L., Castellanos D. A., Cho S. R., Cohen M. A., Cui L., Cummings B. J., Daadi M. M., David S., Deng Y. B., Deshpande D. M., Dhara S. K., Ernsberger U., Fereshteh Karamali, Fouad K., Gage F. H., Golden K. L., Gruner J. A., Haruta M., Hatami M., Hill C. E., Hofstetter C. P., Hong S., Hossein Baharvand, Islam O., Iwanami A., Joannides A. J., Joannides A. J., Kamada T., Kamei N., Karimi-Abdolrezaee S., Kerr D. A., Keyvan-Fouladi N., Kimura H., Koch P., Kumagai G., Li J., Lim M. S., Lindvall O., Livak K. J., Lu P., Lund R. D., Madhavan L., McDonald J. W., Menei P., Meng X. T., Mohammad Hossein Nasr-Esfahani, Mohammad Mardani, Mollamohammadi S., Murray M., Nemati S., Niapour A., Okada S., Olson H. E., Pal R., Papastefanaki F., Parati E. A., Park D. H., Parr A. M., Pearse D. D., Pearse D. D., Pfeifer K., Pincus D. W., Ramer L. M., Roy N. S., Salehi M., Sasaki M., Shin S., Shiva Nemati, Smith R., Takami T., Tetzlaff W., Thuret S., Tobias C. A., Tsuji O., Vargas M. E., Wang G., Webber D. J., Widenfalk J., Willerth S. M., Yan J., Yan J., Zahra Taghipour, Zeng Y. S., Zhang X., Zhang Y. Q.   +97 more
core   +2 more sources

Spatiomechanical Modulation of EphB4-Ephrin-B2 Signaling in Neural Stem Cell Differentiation. [PDF]

, 2018
Interactions between EphB4 receptor tyrosine kinases and their membrane-bound ephrin-B2 ligands on apposed cells play a regulatory role in neural stem cell differentiation.
Chung, Jean, Dong, Meimei, Groves, Jay, Lee, Young, SCHAFFER, David, Spelke, Dawn, Yu, Cheng-Han   +6 more
core   +2 more sources

Involvement of the Acyl-CoA binding domain containing 7 in the control of food intake and energy expenditure in mice

eLife, 2016
Acyl-CoA binding domain-containing 7 (Acbd7) is a paralog gene of the diazepam-binding inhibitor/Acyl-CoA binding protein in which single nucleotide polymorphism has recently been associated with obesity in humans.
Damien Lanfray, Alexandre Caron, Marie-Claude Roy, Mathieu Laplante, Fabrice Morin, Jérôme Leprince, Marie-Christine Tonon, Denis Richard   +7 more
doaj   +1 more source