Results 31 to 40 of about 277,318 (263)
Neuronal differentiation by analogs of staurosporine [PDF]
Neurochemistry International, 2010 RGC-5 cells are transformed cells that express several surface markers characteristic of neuronal precursor cells, but resemble glial cells morphologically and divide in culture. When treated with the apoptosis-inducing agent staurosporine, RGC-5 cells assume a neuronal morphology, extend neurites, stop dividing, and express ion channels without acute ...
Alex F, Thompson, Leonard A, Levin
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Life, 2023 Phytocannabinoids, with their variety of beneficial effects, represent a valid group of substances that could be employed as neurogenesis-enhancers or neuronal differentiation inducers.
Andrea Valeri +5 more
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Frontiers in Psychiatry, 2019 Adrenocorticotropic hormone together with arginine vasopressin and oxytocin, the neuropeptides regulating the stress response and the hypothalamic-pituitary-adrenal axis activity, are known to modulate aggressive behavior.
Henning Vaeroy +2 more
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Frontiers in Genome Editing, 2022 Neuronal differentiation is a complex process whose dysfunction can lead to brain disorders. The development of new tools to target specific steps in the neuronal differentiation process is of paramount importance for a better understanding of the ...
Sara Riccardi +5 more
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Differential localization of acetylcholinesterase in neuronal and non‐neuronal cells [PDF]
Journal of Cellular Biochemistry, 2005 AbstractAcetylcholinesterase (AChE) expression is regulated in cell types at the transcriptional and translational levels. In this study, we characterized and compared AChE catalytic activity, mRNA, protein expression, and protein localization in a variety of neuronal (SH‐SY5Y neuroblastoma and primary cerebellar granule neurons (CGN)) and non‐neuronal
Matthew D, Thullbery +4 more
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eLife, 2022 Reconstruction of prototypic three-dimensional (3D) atlases at the scale of whole tissues or organs requires specific methods to be developed. We have established a digital 3D-atlas maker (DAMAKER) and built a digital 3D-atlas to monitor the changes in ...
Matthias Blanc +3 more
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CIC is a Critical Regulator of Neuronal Differentiation [PDF]
JCI Insight, 2019 ABSTRACT Capicua (CIC), a member of the high mobility group (HMG)-box superfamily of transcriptional repressors, is frequently mutated in human oligodendrogliomas. But its function in brain development and tumorigenesis remains poorly understood. Here, we report that brain-specific deletion of Cic
Hwang, Inah +5 more
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Ionizing Radiation Induces Altered Neuronal Differentiation by mGluR1 through PI3K-STAT3 Signaling in C17.2 Mouse Neural Stem-Like Cells. [PDF]
PLoS ONE, 2016 Most studies of IR effects on neural cells and tissues in the brain are still focused on loss of neural stem cells. On the other hand, the effects of IR on neuronal differentiation and its implication in IR-induced brain damage are not well defined.
Hyeon Soo Eom +6 more
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iASPP regulates neurite development by interacting with Spectrin proteins
Frontiers in Molecular Neuroscience, 2023 IntroductionSince its discovery in 1999, a substantial body of research has shown that iASPP is highly expressed in various kinds of tumors, interacts with p53, and promotes cancer cell survival by antagonizing the apoptotic activity of p53. However, its
Junhao Wang +4 more
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Cellular Acetylcholine Content and Neuronal Differentiation [PDF]
Journal of Neurochemistry, 1997 Abstract: N18TG2 neuroblastoma clone is defective for biosynthetic neurotransmitter enzymes; its inability to establish functional synapses is overcome in the neuroblastoma × glioma 108CC15, where acetylcholine synthesis is also activated. These observations suggest a possible relation between the ability to produce acetylcholine and the capability to ...
F. Bignami +6 more
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