Results 41 to 50 of about 1,427,821 (305)

Cellular Acetylcholine Content and Neuronal Differentiation [PDF]

Journal of Neurochemistry, 1997
Abstract: N18TG2 neuroblastoma clone is defective for biosynthetic neurotransmitter enzymes; its inability to establish functional synapses is overcome in the neuroblastoma × glioma 108CC15, where acetylcholine synthesis is also activated. These observations suggest a possible relation between the ability to produce acetylcholine and the capability to ...
F. Bignami, P. Bevilacqua, BIAGIONI, Stefano, DE JACO, Antonella, F. Casamenti, A. Felsani, TOCCO, Gabriella   +6 more
openaire   +5 more sources

Octadecaneuropeptide (ODN) Induces N2a Cells Differentiation through a PKA/PLC/PKC/MEK/ERK-Dependent Pathway: Incidence on Peroxisome, Mitochondria, and Lipid Profiles

Molecules, 2019
Neurodegenerative diseases are characterized by oxidative stress, mitochondrial damage, and death of neuronal cells. To counteract such damage and to favor neurogenesis, neurotrophic factors could be used as therapeutic agents. Octadecaneuropeptide (ODN),
Amira Namsi, Thomas Nury, Amira. S. Khan, Jérôme Leprince, David Vaudry, Claudio Caccia, Valerio Leoni, Atanas G. Atanasov, Marie-Christine Tonon, Olfa Masmoudi-Kouki, Gérard Lizard   +10 more
doaj   +1 more source

Unidirectional Neuronal Cell growth and Differentiation on Aligned Polyhydroxyalkanoate Blend Microfibres with Varying Diameters [PDF]

, 2019
Polyhydroxyalkanoates (PHAs) are a family of prokaryotic-derived biodegradable and biocompatible natural polymers known to exhibit neuroregenerative properties. In this work, poly(3-hydroxybutyrate), P(3HB) and poly(3-hydroxyoctanoate), P(3HO), have been
Lizarraga Valderrama, L., Lizarraga‐Valderrama, L.R., Claeyssens, F., Claeyssens, F, Knowles, J.C., Roy, I., Knowles, JC, Lizarraga-Valderrama, LR, Roy, I, Taylor, C.S., Haycock, JW, Taylor, CS, Haycock, J.W.   +12 more
core   +1 more source

Involvement of the Acyl-CoA binding domain containing 7 in the control of food intake and energy expenditure in mice

eLife, 2016
Acyl-CoA binding domain-containing 7 (Acbd7) is a paralog gene of the diazepam-binding inhibitor/Acyl-CoA binding protein in which single nucleotide polymorphism has recently been associated with obesity in humans.
Damien Lanfray, Alexandre Caron, Marie-Claude Roy, Mathieu Laplante, Fabrice Morin, Jérôme Leprince, Marie-Christine Tonon, Denis Richard   +7 more
doaj   +1 more source

Upregulation of Apol8 by Epothilone D facilitates the neuronal relay of transplanted NSCs in spinal cord injury

Stem Cell Research & Therapy, 2021
Background Microtubule-stabilizing agents have been demonstrated to modulate axonal sprouting during neuronal disease. One such agent, Epothilone D, has been used to treat spinal cord injury (SCI) by promoting axonal sprouting at the lesion site after ...
Weiwei Xue, Haipeng Zhang, Yongheng Fan, Zhifeng Xiao, Yannan Zhao, Weiyuan Liu, Bai Xu, Yanyun Yin, Bing Chen, Jiayin Li, Yi Cui, Ya Shi, Jianwu Dai   +12 more
doaj   +1 more source

p25/Cdk5-mediated retinoblastoma phosphorylation is an early event in neuronal cell death [PDF]

, 2005
In large models of neuronal cell death, there is a tight correlation between Cdk5 deregulation and cell-cycle dysfunction. However, pathways that link Cdk5 to the cell cycle during neuronal death are still unclear.
Sambo, Anne-Véronique, Philippe Bertrand, Bégard, Séverine, Luc Buée, André Delacourte, Séverine Bégard, Bertrand, Philippe, Hamdane, Malika, Katharina Schindowski, Bretteville, Alexis, Anne-Véronique Sambo, Schindowski, Katharina, Delacourte, André, Buée, Luc, Malika Hamdane, Alexis Bretteville   +15 more
core   +1 more source

Evidence‐Informed Multidisciplinary Consensus Guidance for the Psychosocial Care of Adolescents With High‐Risk Cancer: Recommendations From the Italian Association of Pediatric Hematology and Oncology

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Adolescents with high‐risk cancer face complex developmental, psychosocial, and ethical challenges that extend beyond disease‐directed treatment. Although international recommendations exist for communication, psychosocial care, pediatric palliative care, survivorship, and shared decision‐making, these have largely evolved within ...
Johanna M. C. Blom, Dorella Scarponi, Giulia Zucchetti, Teresa Perillo, Maria Montanaro, Elisa Marconi, Chiara Rutigliano, Paolo Colavero, Paola Quarello, Marina Bertolotti, Monica Cellini, Carlo Clerici, Maurizio Mascarin, Francesca Bomben, Andrea Ferrari, the expert workgroup   +15 more
wiley   +1 more source

BMAA effects neuronal differentiation.

, 2023
Treatment with all-trans retinoic acid (ATRA) induces neuronal differentiation of IMR-32 cells. Wnt enhances this process (A). Micrographs show neuronal differentiation of IMR-32 cells treated with BMAA and ATRA for 5 days (B).
Bryan Burton (14768907), Ellie Moore (14768919), Karly Marx (14768910), Kaylei Wilcox (14768916), Keith Osowski (14768922), Kate Collins (7193567), Jarron Rowe (14768928), Jordan Riley (14768925), Matthew Pawlus (14768931), Jordan Brooks (11151486), Abigail Renner (14768913)   +10 more
core   +1 more source

Caveolin-1 plays a crucial role in inhibiting neuronal differentiation of neural stem/progenitor cells via VEGF signaling-dependent pathway. [PDF]

PLoS ONE, 2011
In the present study, we aim to elucidate the roles of caveolin-1(Cav-1), a 22 kDa protein in plasma membrane invaginations, in modulating neuronal differentiation of neural progenitor cells (NPCs).
Yue Li, Jianmin Luo, Wui-Man Lau, Guoqing Zheng, Shuping Fu, Ting-Ting Wang, He-Ping Zeng, Kwok-Fai So, Sookja Kim Chung, Yao Tong, Kejian Liu, Jiangang Shen   +11 more
doaj   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source