Results 291 to 300 of about 999,561 (325)

Calcineurin regulation of neuronal plasticity

Biochemical and Biophysical Research Communications, 2003
From the most basic of nervous systems to the intricate circuits found within the human brain, a fundamental requirement of neuronal function is that it be malleable, altering its output based upon experience. A host of cellular proteins are recruited for this purpose, which themselves are regulated by protein phosphorylation.
Rachel D. Groth, Robert L. Dunbar, Paul G. Mermelstein   +2 more
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Neuromodulation and Neuronal Plasticity

2009
Publisher Summary This chapter reviews the neuronal plasticity, discusses the evidence of plasticity in a number of disease states in which neuromodulation is a potential therapy, and reviews the evidence of the connection between neuromodulation therapy and neuronal plasticity. Advances in basic and clinical neurosciences over the past 20 years have
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Psychomotor stimulants and neuronal plasticity

Neuropharmacology, 2004
Considerable evidence suggests that neuroadaptations leading to addiction involve the same glutamate-dependent cellular mechanisms that enable learning and memory. Long-term potentiation (LTP) and long-term depression (LTD) have therefore become an important focus of addiction research. This article reviews: (1) basic mechanisms underlying LTP and LTD,
Simona Mangiavacchi, Xiu Sun, Marina E. Wolf, Steven Z. Chao   +3 more
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Neuronal plasticity and Parkinson disease

Molecular and Chemical Neuropathology, 1995
The data reviewed here demonstrate a capacity for neuronal plasticity in the aged human brain, even when affected by neurodegenerative disorders. However, given their location and environment, these morphological changes may have beneficial or deleterious consequences.
Philippe Anglade, E. C. Hirsch, S. Tsuji, Yves Agid   +3 more
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Diabetes and the plasticity of sensory neurons

Neuroscience Letters, 2015
Diabetes mellitus targets sensory neurons during the development of peripheral neuropathy. While polyneuropathy is often routinely considered as another 'microvascular' complication of diabetes mellitus, this concept may no longer address the complexities and unique qualities of direct neuronal involvement. The list of altered molecules and pathways in
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Cellular and molecular neuronal plasticity

2015
The brain has the capability to adapt to function when tissue is compromised. This capability of adaptation paves the road to recovery and allows for rehabilitation after a traumatic brain injury (TBI). This chapter addresses neuroplasticity within the context of TBI.
Grace S. Griesbach, David A. Hovda
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Hebb and homeostasis in neuronal plasticity

Current Opinion in Neurobiology, 2000
The positive-feedback nature of Hebbian plasticity can destabilize the properties of neuronal networks. Recent work has demonstrated that this destabilizing influence is counteracted by a number of homeostatic plasticity mechanisms that stabilize neuronal activity.
Gina G. Turrigiano, Sacha B. Nelson
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Lipid Peroxides and Neuronal Plasticity

1999
Long-term potentiation (LTP) of synaptic transmission is a well defined form of neuronal plasticity. The induction of LTP at perforant path-dentate granule cell and Schaffer collateral-CA1 pyramidal cell synapses of the hippocampus is known to require influx of Ca2+ through postsynaptic N-methy1-D-aspartate (NMDA) receptors, while the expression of LTP
Tomokatsu Hori, Katsuhiko Ogata, Takao Shimizu, Nobuaki Hori, Makoto Nishiyama, Takashi Watanabe, Eiichi Maru, Keiichi Watanabe   +7 more
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Plasticity in Dopamine Neurons

2016
Dopamine (DA) neurons in the ventral midbrain can act as a point of convergence for information arriving from various glutamate and GABA afferents. The synaptic inputs from these afferents to midbrain DA neurons undergo various forms of plasticity. Both excitatory and inhibitory afferents can undergo different forms of long-term potentiation (LTP) and ...
S.A. Quraishi, C.A. Paladini
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Neuronal Modulation and Plasticity in Vitro

1994
Publisher Summary This chapter emphasizes on the contribution that in vitro studies that have made in determining the influence of trophic factors and physical environment on neuronal survival and phenotypic plasticity. It also considers the control of neurite extension and growth cone activity in finding pathways and establishing synaptic ...
Zhi-Gang Jiang, Robert A. Smith
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