Results 71 to 80 of about 2,607,777 (388)
Critical Role of Astrocytic Polyamine and GABA Metabolism in Epileptogenesis
Frontiers in Cellular Neuroscience, 2022 Accumulating evidence indicate that astrocytes are essential players of the excitatory and inhibitory signaling during normal and epileptiform activity via uptake and release of gliotransmitters, ions, and other substances.
Zsolt Kovács +8 more
doaj +1 more source
Optimal sizes of dendritic and axonal arbors in a topographic projection
, 1999 I consider a topographic projection between two neuronal layers with different densities of neurons. Given the number of output neurons connected to each input neuron (divergence) and the number of input neurons synapsing on each output neuron ...
Chklovskii, Dmitri B.
core +2 more sources
Disruption of SETD3‐mediated histidine‐73 methylation by the BWCFF‐associated β‐actin G74S mutation
FEBS Letters, EarlyView.The β‐actin G74S mutation causes altered interaction of actin with SETD3, reducing histidine‐73 methylation efficiency and forming two distinct actin variants. The variable ratio of these variants across cell types and developmental stages contributes to tissue‐specific phenotypical changes. This imbalance may impair actin dynamics and mechanosensitive
Anja Marquardt +8 more
wiley +1 more source
Fibrinogen Chains Intrinsic to the Brain
Frontiers in Neuroscience, 2019 We observed fine fibrin deposition along the paravascular spaces in naive animals, which increased dramatically following subarachnoid hemorrhage (SAH). Following SAH, fibrin deposits in the areas remote from the hemorrhage.
Eugene V. Golanov +5 more
doaj +1 more source
Neurons with stereotyped and rapid responses provide a reference frame for relative temporal coding in primate auditory cortex [PDF]
, 2012 The precise timing of spikes of cortical neurons relative to stimulus onset carries substantial sensory information. To access this information the sensory systems would need to maintain an internal temporal reference that reflects the precise stimulus ...
Brasselet, Romain +4 more
core +1 more source
Purification tags markedly affect self‐aggregation of CPEB3
FEBS Letters, EarlyView.Although recombinant proteins are used to study protein aggregation in vitro, uncleaved tags can interfere with accurate interpretation. Our findings demonstrate that His₆‐GFP and His₁₂ tags significantly affect liquid droplet and amyloid fibril formation in the intrinsically disordered region (IDR) of mouse cytoplasmic polyadenylation element‐binding ...
Harunobu Saito +6 more
wiley +1 more source
Analyzing Autoencoder-Based Intrusion Detection System Performance
Journal of Information Security and Cybercrimes Research, 2023 The rise in cyberattacks targeting critical network infrastructure has spurred an increased emphasis on the development of robust cybersecurity measures.
Seiba Alhassan +4 more
doaj +1 more source
Data-driven modeling of the olfactory neural codes and their dynamics in the insect antennal lobe [PDF]
, 2013 Recordings from neurons in the insects' olfactory primary processing center, the antennal lobe (AL), reveal that the AL is able to process the input from chemical receptors into distinct neural activity patterns, called olfactory neural codes.
Kutz, J. Nathan +2 more
core +3 more sources
Single‐cell insights into the role of T cells in B‐cell malignancies
FEBS Letters, EarlyView.Single‐cell technologies have transformed our understanding of T cell–tumor cell interactions in B‐cell malignancies, revealing new T‐cell subsets, functional states, and immune evasion mechanisms. This Review synthesizes these findings, highlighting the roles of T cells in pathogenesis, progression, and therapy response, and underscoring their ...
Laura Llaó‐Cid
wiley +1 more source
Cluster synchronization in an ensemble of neurons interacting through chemical synapses
, 2005 In networks of periodically firing spiking neurons that are interconnected with chemical synapses, we analyze cluster state, where an ensemble of neurons are subdivided into a few clusters, in each of which neurons exhibit perfect synchronization.
A. L. Hodgkin +5 more
core +1 more source