Results 1 to 10 of about 2,037,833 (212)

An Epidemiological Study of Neuropathic Pain Symptoms in Canadian Adults [PDF]

Pain Research and Management, 2016
The reported prevalence of neuropathic pain ranges from 6.9% to 10%; however the only Canadian study reported 17.9%. The objective of this study was to describe the epidemiology of neuropathic pain in Canada.
Elizabeth G. VanDenKerkhof, Elizabeth G. Mann, Nicola Torrance, Blair H. Smith, Ana Johnson, Ian Gilron   +5 more
doaj   +7 more sources

Treatment of neuropathic pain in cancer survivors: a scoping review of pharmacological, exercise, and psychosocial interventions [PDF]

Acta Oncologica
Background and purpose: Neuropathic pain is a debilitating late effect among cancer survivors. This scoping review aims to provide an overview of pharmacological, psychological, and exercise interventions for neuropathic pain among cancer survivors and ...
Ellen Lund Schaldemose, Bolette Skjødt Rafn, Pernille Envold Bidstrup, Agon Olloni, Katrin Schättiger, Peter Christensen, Cæcilie Borregaard Myrhøj, Maja Johannsen Lindberg, Christoffer Johansen, Sandra Jensen, Ida Hovdenak, Sasja Jul Håkonsen, Lise Ventzel   +12 more
doaj   +2 more sources

Epidemiology of neuropathic pain: an analysis of prevalence and associated factors in UK Biobank

PAIN Reports, 2023
Supplemental Digital Content is Available in the Text. An analysis of UK Biobank participants who completed a detailed pain questionnaire identified factors associated with neuropathic pain (NeuP) vs no chronic pain and non-NeuP and estimated the ...
G. Baskozos, H. Hébert, Mathilde M V Pascal, A. Themistocleous, G. Macfarlane, D. Wynick, David L H Bennett, Blair H. Smith   +7 more
semanticscholar   +1 more source

Advances and challenges in neuropathic pain: a narrative review and future directions.

British Journal of Anaesthesia, 2023
Over the past few decades, substantial advances have been made in neuropathic pain clinical research. An updated definition and classification have been agreed.
N. Attal, D. Bouhassira, L. Colvin
semanticscholar   +1 more source

RNA profiling of human dorsal root ganglia reveals sex-differences in mechanisms promoting neuropathic pain.

Brain : a journal of neurology, 2022
Neuropathic pain is a leading cause of high impact pain, is often disabling and is poorly managed by current therapeutics. Here we focused on a unique group of neuropathic pain patients undergoing thoracic vertebrectomy where the dorsal root ganglia is ...
P. Ray, Stephanie I. Shiers, James P Caruso, Diana Tavares-Ferreira, Ishwarya Sankaranarayanan, Megan L. Uhelski, Yan Li, Robert Y. North, C. Tatsui, G. Dussor, M. Burton, P. Dougherty, Theodore John Price   +12 more
semanticscholar   +1 more source

Contribution of colony-stimulating factor 1 to neuropathic pain

PAIN Reports, 2021
This review discusses recent research and the unanswered questions regarding CSF1/CSF1R-mediated microglial and macrophage signaling in the generation of neuropathic pain.
Xiaobing Yu, Allan Basbaum, Zhonghui Guan   +2 more
semanticscholar   +1 more source

Comparing objective cognitive impairments in patients with peripheral neuropathic pain or fibromyalgia

Scientific Reports, 2021
Existing studies on cognitive impairments in chronic pain do not investigate peripheral neuropathic pain (PNP) or compare pain conditions in a satisfactory manner. Here we aimed to compare executive dysfunctions in PNP patients with fibromyalgia (FM) and
Henrik Børsting Jacobsen, Tore C. Stiles, Audun Stubhaug, Nils Inge Landrø, Per Hansson   +4 more
doaj   +1 more source

Enriched enrollment randomized double-blind placebo-controlled cross-over trial with phenytoin cream in painful chronic idiopathic axonal polyneuropathy (EPHENE): a study protocol

Trials, 2022
Background Patients with chronic idiopathic axonal polyneuropathy (CIAP) can have neuropathic pain that significantly impacts quality of life. Oral neuropathic pain medication often has insufficient pain relief and side effects.
David J. Kopsky, Ruben P. A. van Eijk, Janna K. Warendorf, Jan M. Keppel Hesselink, Nicolette C. Notermans, Alexander F. J. E. Vrancken   +5 more
doaj   +1 more source

Exercise and Neuropathic Pain: A General Overview of Preclinical and Clinical Research

Sports Medicine - Open, 2021
Neuropathic pain is a disease of the somatosensory system that is characterized by tingling, burning, and/or shooting pain. Medication is often the primary treatment, but it can be costly, thus there is an interest in understanding alternative low-cost ...
B. Leitzelar, K. Koltyn
semanticscholar   +1 more source

Dorsal root ganglion macrophages contribute to both the initiation and persistence of neuropathic pain

Nature Communications, 2020
Paralleling the activation of dorsal horn microglia after peripheral nerve injury is a significant expansion and proliferation of macrophages around injured sensory neurons in dorsal root ganglia (DRG).
Xiaobing Yu, Hongjun Liu, K. Hamel, Maelig G. Morvan, Stephen Yu, Jacqueline Leff, Zhonghui Guan, J. Braz, A. Basbaum   +8 more
semanticscholar   +1 more source