Инновационная медицина Кубани, 2021 Background Chronic neuropathic pain is a common occurrence, its prevalence ranges from 7 to 10% of the total population. Currently, the only official document that includes neuropathic pain is the International Classification of Headaches Disorders (ICHD-
V. A. Koriachkin +2 more
doaj +3 more sources
A modified score to identify and discriminate neuropathic pain: a study on the German version of the neuropathic pain symptom inventory (NPSI) [PDF]
BMC Neurology, 2011 Background Neuropathic pain must be correctly diagnosed for optimal treatment. The questionnaire named Neuropathic Pain Symptom Inventory (NPSI) was developed in its original French version to evaluate the different symptoms of neuropathic pain.
Lungenhausen Margitta +5 more
doaj +5 more sources
Dorsal root ganglion macrophages contribute to both the initiation and persistence of neuropathic pain. [PDF]
Nature Communications, 2020 Paralleling the activation of dorsal horn microglia after peripheral nerve injury is a significant expansion and proliferation of macrophages around injured sensory neurons in dorsal root ganglia (DRG).
Basbaum, Allan I +8 more
core +3 more sources
Translational investigation and treatment of neuropathic pain [PDF]
Molecular Pain, 2012 Neuropathic pain develops from a lesion or disease affecting the somatosensory system. Translational investigations of neuropathic pain by using different animal models reveal that peripheral sensitization, spinal and cortical plasticity may play ...
Xu Bo +4 more
doaj +4 more sources
An Epidemiological Study of Neuropathic Pain Symptoms in Canadian Adults [PDF]
Pain Research and Management, 2016 The reported prevalence of neuropathic pain ranges from 6.9% to 10%; however the only Canadian study reported 17.9%. The objective of this study was to describe the epidemiology of neuropathic pain in Canada.
Elizabeth G. VanDenKerkhof +5 more
doaj +7 more sources
Comparative analysis of chronic neuropathic pain and pain assessment in companion animals and humans [PDF]
Frontiers in Veterinary ScienceChronic neuropathic pain is underdiagnosed in companion animals. This paper will review the definition of pain and how classification and grading of neuropathic pain can be applied from human to veterinary medicine to increase the recognition of and the ...
Rell L. Parker
doaj +2 more sources
Somatosensory profiles but not numbers of somatosensory abnormalities of neuropathic pain patients correspond with neuropathic pain grading. [PDF]
PLoS ONE, 2012 Due to the lack of a specific diagnostic tool for neuropathic pain, a grading system to categorize pain as 'definite', 'probable', 'possible' and 'unlikely' neuropathic was proposed.
Karl-Heinz Konopka +8 more
doaj +5 more sources
Emerging Role of Schwann Cells in Neuropathic Pain: Receptors, Glial Mediators and Myelination
Frontiers in Cellular Neuroscience, 2019 Neuropathic pain caused by nerve injury or disease remains a major challenge for modern medicine worldwide. Most of the pathogenic mechanisms underlying neuropathic pain are centered on neuronal mechanisms.
Gang Chen
exaly +2 more sources
Epigenetic Modifications Associated to Neuroinflammation and Neuropathic Pain After Neural Trauma
Frontiers in Cellular Neuroscience, 2018 Accumulating evidence suggests that epigenetic alterations lie behind the induction and maintenance of neuropathic pain. Neuropathic pain is usually a chronic condition caused by a lesion, or pathological change, within the nervous system.
Clara Penas, Xavier Navarro
exaly +2 more sources
Are voltage-gated sodium channels on the dorsal root ganglion involved in the development of neuropathic pain? [PDF]
Molecular Pain, 2011 Neuropathic pain is a common clinical condition. Current treatments are often inadequate, ineffective, or produce potentially severe adverse effects. Understanding the mechanisms that underlie the development and maintenance of neuropathic pain will be ...
Li Yun-Qing +3 more
doaj +4 more sources