Results 1 to 10 of about 102,098 (310)

Protein Kinases as Mediators for miRNA Modulation of Neuropathic Pain [PDF]

Cells
Neuropathic pain is a chronic condition resulting from injury or dysfunction in the somatosensory nervous system, which leads to persistent pain and a significant impairment of quality of life.
Leah Chang, Zala Čok, Lei Yu
doaj   +2 more sources

Comparing objective cognitive impairments in patients with peripheral neuropathic pain or fibromyalgia

Scientific Reports, 2021
Existing studies on cognitive impairments in chronic pain do not investigate peripheral neuropathic pain (PNP) or compare pain conditions in a satisfactory manner. Here we aimed to compare executive dysfunctions in PNP patients with fibromyalgia (FM) and
Henrik Børsting Jacobsen, Tore C. Stiles, Audun Stubhaug, Nils Inge Landrø, Per Hansson   +4 more
doaj   +1 more source

Enriched enrollment randomized double-blind placebo-controlled cross-over trial with phenytoin cream in painful chronic idiopathic axonal polyneuropathy (EPHENE): a study protocol

Trials, 2022
Background Patients with chronic idiopathic axonal polyneuropathy (CIAP) can have neuropathic pain that significantly impacts quality of life. Oral neuropathic pain medication often has insufficient pain relief and side effects.
David J. Kopsky, Ruben P. A. van Eijk, Janna K. Warendorf, Jan M. Keppel Hesselink, Nicolette C. Notermans, Alexander F. J. E. Vrancken   +5 more
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Neuropathic pain

Инновационная медицина Кубани, 2021
Background Chronic neuropathic pain is a common occurrence, its prevalence ranges from 7 to 10% of the total population. Currently, the only official document that includes neuropathic pain is the International Classification of Headaches Disorders (ICHD-
V. A. Koriachkin, A. P. Spasova, V. V. Khinovker   +2 more
doaj   +1 more source

Relationship between Nontraumatic Shoulder Disorders and Neuropathic Pain: Retrospective Observational Analyses of Clinical Features and Background Factors

Anesthesiology Research and Practice, 2023
Background. Accurate identification of neuropathic pain is necessary for appropriate treatment; however, the relationship between nontraumatic shoulder disorders and neuropathic pain remains unknown.
Tsuyoshi Sasaki, Hitoshi Shitara, Tsuyoshi Tajika, Tsuyoshi Ichinose, Noritaka Hamano, Masataka Kamiyama, Atsushi Yamamoto, Tsutomu Kobayashi, Kenji Takagishi, Hirotaka Chikuda   +9 more
doaj   +1 more source

Phenytoin Cream for the Treatment of Neuropathic Pain: Case Series

Pharmaceuticals, 2018
BACKGROUND: Neuropathic pain can be disabling, and is often difficult to treat. Within a year, over half of all patients stop taking their prescribed neuropathic pain medication, which is most probably due to side effects or disappointing analgesic ...
David J. Kopsky, Jan M. Keppel Hesselink
doaj   +1 more source

Single-Blind Placebo-Controlled Response Test with Phenytoin 10% Cream in Neuropathic Pain Patients

Pharmaceuticals, 2018
Background: Phenytoin cream applied topically has been explored in neuropathic pain conditions. In several case series, phenytoin 5% and 10% cream could reduce pain in a clinically relevant way with a fast onset of action within 30 min, and with positive
David J. Kopsky, Jan M. Keppel Hesselink   +1 more
doaj   +1 more source

NEUROPATHIC PAIN AS A CHALLENGING CLINICAL ENTITY IN OLDER ADULTS

Anti-Aging Eastern Europe, 2022
Neuropathic pain is a challenging clinical entity in older adults. Certain clinical conditions such as diabetes mellitus, cerebrovascular diseases and infections may lead to neuropathic pain in the elderly.
Ilke Coskun Benlidayi
doaj   +1 more source

Acute lumbar polyradiculoneuropathy as early sign of methotrexate intrathecal neurotoxicity: Case report and literature review

Clinical Case Reports, 2019
Key Clinical Message Acute paraplegia after treatment with intrathecal methotrexate requires a complete spinal cord neuroimaging as well as electrodiagnostic examination.
Carmen Montejo, Judith Navarro‐Otano, Gerard Mayà‐Casalprim, Michela Campolo, Jordi Casanova‐Mollá   +4 more
doaj   +1 more source

Neuropathic pain treatment: still a challenge

Neurology International, 2016
Neuropathic pain (NP) is the result of a series of conditions caused by diseases or lesions to the somatosensory system. Due to the better understanding of NP pathophysiology previously unexplored therapies have been used with encouraging results.
Osvaldo J.M. Nascimento, Bruno L. Pessoa, Marco Orsini, Pedro Ribeiro, Eduardo Davidovich, Camila Pupe, Pedro Moreira Filho, Ricardo Menezes Dornas, Lucas Masiero, Juliana Bittencourt, Victor Hugo Bastos   +10 more
doaj   +1 more source