Trigeminal neuralgia: new classification and diagnostic grading for practice and research [PDF]
Trigeminal neuralgia (TN) is an exemplary condition of neuropathic facial pain. However, formally classifying TN as neuropathic pain based on the grading system of the International Association for the Study of Pain is complicated by the requirement of ...
CRUCCU, Giorgio+8 more
core +2 more sources
Managing the symptoms of neuropathic pain: An exploration of patients' experiences [PDF]
The debilitating effects of chronic neuropathic pain on everyday life are considerable but little is known about how individual sufferers manage these effects.
Bennett+25 more
core +1 more source
Use of the painDETECT tool in rheumatoid arthritis suggests neuropathic and sensitization components in pain reporting. [PDF]
Rheumatoid arthritis (RA) is an inflammatory autoimmune condition typified by systemic inflammation targeted toward synovial joints. Inhibition of proinflammatory networks by disease-modifying antirheumatic drugs, eg, methotrexate and biologic therapies,
Ahmed, S+4 more
core +2 more sources
A genome-wide association study provides evidence of sex-specific involvement of Chr1p35.1 (ZSCAN20-TLR12P) and Chr8p23.1 (HMGB1P46) with diabetic neuropathic pain [PDF]
Neuropathic pain is defined as pain arising as a direct consequence of a lesion or a disease affecting the somatosensory system and it affects around 1 in 4 diabetic patients in the UK.
Abbott+64 more
core +4 more sources
A genome-wide association study suggests an association of Chr8p21.3 (GFRA2) with diabetic neuropathic pain [PDF]
BACKGROUND: Neuropathic pain, caused by a lesion or a disease affecting the somatosensory system, is one of the most common complications in diabetic patients.
+11 more
core +3 more sources
Genitofemoral neuralgia : adding to the burden of chronic vulvar pain [PDF]
The vulva is a particularly common locus of chronic pain with neuropathic characteristics that occurs in women of any age, though most women with neuropathic type chronic vulvar pain will remain undiagnosed even following multiple physician visits. Here,
De Muynck, Martine+2 more
core +2 more sources
Apoptotic gene expression in neuropathic pain [PDF]
Pain initiated or caused by a primary lesion or dysfunction in the nervous system is defined as neuropathic pain. It results from direct injury to nerves in the peripheral or central nervous system and is associated with several clinical symptoms ...
Annalucia Migliozzi+6 more
core +2 more sources
Analgesic effectiveness and tolerability of oral oxycodone/naloxone and pregabalin in patients with lung cancer and neuropathic pain. An observational analysis [PDF]
INTRODUCTION: Cancer-related pain has a severe negative impact on quality of life. Combination analgesic therapy with oxycodone and pregabalin is effective for treating neuropathic cancer pain.
Borghesi, Cristina+6 more
core +2 more sources
An epidemiological study of neuropathic pain symptoms in Canadian adults [PDF]
The reported prevalence of neuropathic pain ranges from 6.9% to 10%; however the only Canadian study reported 17.9%. The objective of this study was to describe the epidemiology of neuropathic pain in Canada.
Gilron, Ian+5 more
core +6 more sources
Zinc inhibits TRPV1 to alleviate chemotherapy-induced neuropathic pain [PDF]
Zinc is a transition metal that has a long history of use as an anti-inflammatory agent. It also soothes pain sensations in a number of animal models.
Bavencoffe, Alexis+12 more
core +2 more sources