Results 91 to 100 of about 169,611 (201)

Contemporary views on inflammatory pain mechanisms: TRPing over innate and microglial pathways. [PDF]

, 2016
Tissue injury, whether by trauma, surgical intervention, metabolic dysfunction, ischemia, or infection, evokes a complex cellular response (inflammation) that is associated with painful hyperalgesic states.
Guan, Zhonghui, Hellman, Judith, Schumacher, Mark   +2 more
core   +2 more sources

Neuropathic pain: mechanisms of development, principles of diagnostics and treatment

Медицина болю, 2019
Neuropathic pain is a pain caused by a disease or focal damage to the somatosensory nervous system. The prevalence of chronic pain with neuropathic features in different countries is estimated at 7–10 %.
Dmytro Dmytriiev, Pylyp Prudius, Olesia Zaletskaya, Yevhen Lisak, Yurii Rudnitsky, Natalia Korenchuk   +5 more
doaj   +1 more source

Evaluation of behavior in transgenic mouse models to understand human congenital pain conditions [PDF]

, 2018
BACKGROUND: Containing a brain for signal processing and decision making, and a peripheral component for sensation and response, the nervous system provides higher organisms a powerful method of interacting with their environment.
Bullock, Daniel
core  

Diagnostics and therapy of peripheral neuropathy (literature review)

Acta Biomedica Scientifica, 2015
The review is devoted to diagnostics and treatment of neuropathic pain in patients with peripheral nervous system diseases. Main assessment tools are shown including Visual analog Scale (VAS), Neuropathic Pain Scale (NPS), Leeds Assessment of Neuropathic
G. Y. Levina, Y. N. Bykov, A. S. Borisov
doaj  

Neuropathic pain

Nursing Standard, 2014
Makoto, Tsuda, Katsuyuki, Matsushita, Kazuhide, Inoue   +2 more
openaire   +5 more sources

Pain Catastrophizing Predicts Poor Response to Topical Analgesics in Patients with Neuropathic Pain

Pain Research and Management, 2012
The prevalence of neuropathic pain approaches 10% in Canada and the United States. Given the aging population and the increasing survival rates following interventions for neuropathic pain, the prevalence of neuropathic pain conditions is expected to ...
Tsipora Mankovsky, Mary E Lynch, AJ Clark, J Sawynok, Michael JL Sullivan   +4 more
doaj   +1 more source

Pain type and neuropathic pain components in acute herpes zoster

Ağrı
Objectives: The aim of this study was to investigate the pain type (nociceptive or neuropathic) and neuropathic pain components in patients with acute herpes zoster (HZ).
Hanzade Aybüke Ünal, Neslihan Demirel Öğüt, Emel Güler, Alp Alptekin   +3 more
doaj   +1 more source

Neuropathic pain evaluation tools

Revista Dor
BACKGROUND AND OBJECTIVES: Pain is a subjective symptom which may be measured by means of its several features, such as intensity, quality, location, duration and impact on daily activities.
Fabiola Dach Eckeli, Rosimary Amorim Teixeira, Áquila Lopes Gouvêa   +2 more
doaj   +1 more source

Increased mGluR5 in somatostatin-positive interneurons mediates deactivation of the mPFC in a mouse model of neuropathic pain

Experimental and Molecular Medicine
Understanding the neurobiological alterations associated with neuropathic pain is crucial for treatment interventions, but the underlying mechanisms remain unclear.
Mirae Jang, Jaegeon Lee, Seung Ha Kim, Sang Ho Yoon, Myoung-Hwan Kim, Yong-Seok Lee, Sun Kwang Kim, Geehoon Chung, Sang Jeong Kim   +8 more
doaj   +1 more source

Rapid Isolation of Dorsal Root Ganglion Macrophages. [PDF]

, 2019
There are growing interests to study the molecular and cellular interactions among immune cells and sensory neurons in the dorsal root ganglia after peripheral nerve injury.
Guan, Zhonghui, Leff, Jacqueline, Yu, Xiaobing   +2 more
core