Results 121 to 130 of about 185,348 (295)
The authors develop mouse models by mimicking peripheral vascular diseases, combining multiple strategies and transgenic mouse lines, to demonstrate that ECs, but not macrophages or SMCs, play an active role mediated by endothelial ET‐1/neural ETAR signaling and beyond endothelial homeostatic angiocrine by driving protective pain through the ...
Zuo‐Jie Jiang +28 more
wiley +1 more source
A study of pain threshold in diabetics with neuropathic foot lesions. [PDF]
Pamela M. Le Quesne, Clare J. Fowler
openalex +1 more source
A randomized placebo-controlled pilot study of the efficacy and safety of D-cycloserine in people with chronic back pain. [PDF]
BACKGROUND: Few effective pharmacological treatment options exist for chronic back pain, the leading cause of disability in the US, and all are associated with significant adverse effects. OBJECTIVE: To determine the efficacy and safety of D-cycloserine,
Apkarian, A. Vania +5 more
core +2 more sources
Artificial Intelligence for Bone: Theory, Methods, and Applications
Advances in artificial intelligence (AI) offer the potential to improve bone research. The current review explores the contributions of AI to pathological study, biomarker discovery, drug design, and clinical diagnosis and prognosis of bone diseases. We envision that AI‐driven methodologies will enable identifying novel targets for drugs discovery. The
Dongfeng Yuan +3 more
wiley +1 more source
Epineurial Peptides: A Role in Neuropathic Pain? [PDF]
Douglas W. Zochodne
openalex +1 more source
Toward Natural Limb Function: A New Era in Prosthetic Innovation
The past decade has witnessed groundbreaking clinical implementation of neuroprosthetic limbs driven by signals from peripheral targets (eg, nerves and muscle) and the brain to restore limb function for individuals with limb loss or impairment. In this review, we highlight recent key clinical trials in peripheral neuroprosthetic interfaces directly ...
Yucheng Tian +4 more
wiley +1 more source
Diagnostics and therapy of peripheral neuropathy (literature review)
The review is devoted to diagnostics and treatment of neuropathic pain in patients with peripheral nervous system diseases. Main assessment tools are shown including Visual analog Scale (VAS), Neuropathic Pain Scale (NPS), Leeds Assessment of Neuropathic
G. Y. Levina, Y. N. Bykov, A. S. Borisov
doaj
Neuropathic Pain Can Be Relieved by Drugs That Are Use-dependent Sodium Channel Blockers [PDF]
Darrell L. Tanelian, William G. Brose
openalex +1 more source
Biallelic Variants in the DARS2 Gene as a Novel Cause of Axonal Charcot–Marie–Tooth Disease
Objective Charcot–Marie–Tooth (CMT) disease is a heterogeneous group of genetic neuropathies, with >90 genes identified. Several aminoacyl‐tRNA synthetases have been linked to CMT. DARS2, encoding the mitochondrial aspartyl‐tRNA synthetase, has been typically associated with leukoencephalopathy with brainstem and spinal cord involvement and lactate ...
Berta Estévez‐Arias +23 more
wiley +1 more source
DOI:10.3969/j.issn.1672-6731.2010.06 ...
openaire +6 more sources

