Results 41 to 50 of about 185,348 (295)

Management of neuropathic pain [PDF]

Journal of General and Family Medicine, 2017
AbstractNeuropathic pain is intractable pain caused by damage to the nervous system. Recent approval and expansion of the indications of a series of drugs are expected to improve the treatment strategies for neuropathic pain. Here, we present an outline of pain transmission pathways and relevant pharmacological effects, along with points to consider in
Masahiro Nomoto, Noriko Nishikawa
openaire   +3 more sources

NGX-4010, a capsaicin 8% patch, for the treatment of painful HIV-associated distal sensory polyneuropathy: integrated analysis of two phase III, randomized, controlled trials [PDF]

, 2013
BACKGROUND HIV-associated distal sensory polyneuropathy (HIV-DSP) is the most frequently reported neurologic complication associated with HIV infection.
Brew, Bruce J, Brown, Stephen, Fisher, Martin, Larbalestier, Nicholas, Moyle, Graeme, Orkin, Chloe, Schifitto, Giovanni, Simpson, David M, Tobias, Jeffrey K, Vanhove, Geertrui F   +9 more
core   +1 more source

Possible Neuropathic Pain in Patients with Osteoarthritis of the Knee Before and After Total Knee Arthroplasty

Journal of Pain Research, 2021
Masahiro Hasegawa, Shine Tone, Yohei Naito, Akihiro Sudo Department of Orthopaedic Surgery, Mie University Graduate School of Medicine, Tsu City, Mie, 514-8507, JapanCorrespondence: Masahiro HasegawaDepartment of Orthopaedic Surgery, Mie University ...
Hasegawa M, Tone S, Naito Y, Sudo A
doaj  

Somatosensory profiles but not numbers of somatosensory abnormalities of neuropathic pain patients correspond with neuropathic pain grading. [PDF]

PLoS ONE, 2012
Due to the lack of a specific diagnostic tool for neuropathic pain, a grading system to categorize pain as 'definite', 'probable', 'possible' and 'unlikely' neuropathic was proposed.
Karl-Heinz Konopka, Marten Harbers, Andrea Houghton, Rudie Kortekaas, Andre van Vliet, Wia Timmerman, Johan A den Boer, Michel M R F Struys, Marten van Wijhe   +8 more
doaj   +1 more source

Multicenter assessment of quantitative sensory testing (QST) for the detection of neuropathic-like pain responses using the topical capsaicin model [PDF]

, 2018
Background: The use of quantitative sensory testing (QST) in multicenter studies has been quite limited, due in part to lack of standardized procedures among centers. Aim: The aim of this study was to assess the application of the capsaicin pain model
Bushnell, M. Catherine, Chouchou, Florian, Ferland, Catherine E., Gandhi, Wiebke, Jackson, Philip L., Lavigne, Gilles, Ma, My-Linh, Marchand, Serge, Michon, Pierre-Emmanuel, Parent, Alexandre J., Rainville, Pierre, Schweinhardt, Petra, Villemure, Chantal, Ware, Mark A.   +13 more
core   +1 more source

Effects of interdisciplinary pain rehabilitation programs on neuropathic and non-neuropathic chronic pain conditions – a registry-based cohort study from Swedish Quality Registry for Pain Rehabilitation (SQRP)

BMC Musculoskeletal Disorders, 2023
Background and aim Neuropathic pain arises as a direct consequence of a lesion or disease affecting the somatosensory system. Pharmacological treatments for neuropathic pain often fail despite following guidelines.
Nazdar Ghafouri, Emmanuel Bäckryd, Elena Dragioti, Marcelo Rivano Fischer, Åsa Ringqvist, Björn Gerdle   +5 more
doaj   +1 more source

A genome-wide association study suggests an association of Chr8p21.3 (GFRA2) with diabetic neuropathic pain [PDF]

, 2014
BACKGROUND: Neuropathic pain, caused by a lesion or a disease affecting the somatosensory system, is one of the most common complications in diabetic patients.
, , Colhoun, H. M., Deshmukh, H. A., Donnelly, L. A., Liu, Y., Meng, W., Morris, A. D., Palmer, C. N. A., Smith, B. H., van Zuydam, N. R., Zhou, K.   +11 more
core   +4 more sources

Ocular neuropathic pain [PDF]

British Journal of Ophthalmology, 2015
As the biological alarm of impending or actual tissue damage, pain is essential for our survival. However, when it is initiated and/or sustained by dysfunctional elements in the nociceptive system, it is itself a disease known as neuropathic pain. While the critical nociceptive system provides a number of protective functions, it is unique in its ...
Rosenthal, Perry, Borsook, David
openaire   +4 more sources

Impact of Neuropathic Pain on Health-Related Quality of Life and Disability in Patients with Chronic Low Back Pain

Türk Osteoporoz Dergisi, 2018
Objective:Low back pain (LBP) is the most common chronic pain disorder worldwide. Chronic LBP is a mixed pain syndrome associated with nociceptive and neuropathic pain mechanisms.
Bilge Kesikburun, Nihal Tezel, Nuray Gülgönül, Emel Ekşioğlu, Aytül Çakcı   +4 more
doaj   +1 more source

Avoiding Catch-22:Validating the PainDETECT in a in a population of patients with chronic pain [PDF]

, 2018
BACKGROUND: Neuropathic pain is defined as pain caused by a lesion or disease of the somatosensory nervous system and is a major therapeutic challenge. Several screening tools have been developed to help physicians detect patients with neuropathic pain ...
Bronkhorst, Ewald M, Huygen, Frank J P M, Schenkels, Marcel J, Steegers, Monique A H, Timmerman, Hans, van Dasselaar, Nick T, Vissers, Kris C P, Wilder-Smith, Oliver H G, Wolff, André P   +8 more
core   +6 more sources