Results 41 to 50 of about 1,846,055 (403)
Neuropathic Pain: Mechanism-Based Therapeutics.
Annual Review of Pharmacology and Toxicology, 2020 Neuropathic pain (NeP) can result from sources as varied as nerve compression, channelopathies, autoimmune disease, and incision. By identifying the neurobiological changes that underlie the pain state, it will be clinically possible to exploit mechanism-
K. Bannister +3 more
semanticscholar +1 more source
Seminars in Neurology, 2018 AbstractNeuropathic pain management is challenging, and typically requires a multifaceted approach. There are several treatment options, both pharmacologic and nonpharmacologic. Of the available pharmacologic agents, those with the strongest supporting evidence include tricyclic antidepressants, serotonin–norepinephrine reuptake inhibitors, and certain
Amanda, Macone, James A D, Otis
openaire +4 more sources
Case Reports in Medicine, 2011 A multimodal stepped care approach has been successfully applied to a patient with complex regional pain syndrome type 1 and severe intractable pain, not responding to regular neuropathic pain medication. The choice to administer drugs in creams was made
David J. Kopsky, Jan M. Keppel Hesselink
doaj +1 more source
Neuropathic pain in the community: prevalence, impact, and risk factors.
Pain, 2020 Neuropathic pain is common (7-10%), and has a high impact on individuals and society. Health-related quality of life was rated as “worse than death” by 17% of people reporting neuropathic pain.
Blair H. Smith, H. Hébert, A. Veluchamy
semanticscholar +1 more source
Opioids for neuropathic pain [PDF]
Cochrane Database of Systematic Reviews, 2006 The use of opioids for neuropathic pain remains controversial. Studies have been small, have yielded equivocal results, and have not established the long-term risk-benefit ratio of this treatment.To assess the efficacy and safety of opioid agonists for the treatment of neuropathic pain.We searched the Cochrane Central Register of Controlled Trials (2nd
E, Eisenberg, E, McNicol, D B, Carr
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Managing the symptoms of neuropathic pain: An exploration of patients' experiences [PDF]
, 2007 The debilitating effects of chronic neuropathic pain on everyday life are considerable but little is known about how individual sufferers manage these effects.
Bennett +25 more
core +1 more source
Neuropathic pain and psychological morbidity in patients with treated leprosy: a cross-sectional prevalence study in Mumbai. [PDF]
PLoS Neglected Tropical Diseases, 2011 BACKGROUND: Neuropathic pain has been little studied in leprosy. We assessed the prevalence and clinical characteristics of neuropathic pain and the validity of the Douleur Neuropathique 4 questionnaire as a screening tool for neuropathic pain in ...
Estrella Lasry-Levy +6 more
doaj +1 more source
Immune or genetic-mediated disruption of CASPR2 causes pain hypersensitivity due to enhanced primary afferent excitability [PDF]
, 2018 Human autoantibodies to contactin-associated protein-like 2 (CASPR2) are often associated with neuropathic pain, and CASPR2 mutations have been linked to autism spectrum disorders, in which sensory dysfunction is increasingly recognized.
Bennett, David L. +39 more
core +2 more sources
The IASP classification of chronic pain for ICD-11: chronic neuropathic pain
Pain, 2019 The upcoming 11th revision of the International Statistical Classification of Diseases and Related Health Problems (ICD) of the World Health Organization (WHO) offers a unique opportunity to improve the representation of painful disorders.
Joachim Scholz +32 more
semanticscholar +1 more source
Walking with Neuropathic Pain: Paradoxical Shift from Burden to Support?
Case Reports in Medicine, 2015 Baclofen 5% cream can be used for the treatment of neuropathic pain. We describe an unusual case of a neuropathic pain patient with spinal cord injury.
David J. Kopsky +2 more
doaj +1 more source