Results 51 to 60 of about 1,846,055 (403)
. Introduction:. Previous studies reported a high prevalence of neuropathic pain in leprosy, being especially present in “pharmacologically cured” patients.
Irina Raicher +9 more
doaj +1 more source
Antinociceptive activity of the S1P-receptor agonist FTY720 [PDF]
FTY720 is a novel immunosuppressive drug that inhibits the egress of lymphocytes from secondary lymphoid tissues and thymus. In its phosphorylated form FTY720 is a potent S1P receptor agonist.
Angioni, Carlo Federico +8 more
core +1 more source
Central neuropathic pain in patients with multiple sclerosis (MS) is a common debilitating symptom, which is mostly treated with tricyclic antidepressants or antiepileptics. Unfortunately, the use of these drugs is often limited due to adverse events. We
David J. Kopsky +2 more
doaj +1 more source
Oral ketamine vs placebo in patients with cancer-related neuropathic pain [PDF]
Ketamine hydrochloride is used as an adjuvant treatment for cancer-related neuropathic pain, but evidence of its effectiveness is limited.1 Findings of a large trial investigating the use of ketamine for general cancer pain were negative, but the ...
Fallon, Marie T. +6 more
core +4 more sources
Multicenter assessment of quantitative sensory testing (QST) for the detection of neuropathic-like pain responses using the topical capsaicin model [PDF]
Background: The use of quantitative sensory testing (QST) in multicenter studies has been quite limited, due in part to lack of standardized procedures among centers. Aim: The aim of this study was to assess the application of the capsaicin pain model
Bushnell, M. Catherine +13 more
core +1 more source
Background Neuropathic pain must be correctly diagnosed for optimal treatment. The questionnaire named Neuropathic Pain Symptom Inventory (NPSI) was developed in its original French version to evaluate the different symptoms of neuropathic pain.
Lungenhausen Margitta +5 more
doaj +1 more source
Use of the painDETECT tool in rheumatoid arthritis suggests neuropathic and sensitization components in pain reporting. [PDF]
Rheumatoid arthritis (RA) is an inflammatory autoimmune condition typified by systemic inflammation targeted toward synovial joints. Inhibition of proinflammatory networks by disease-modifying antirheumatic drugs, eg, methotrexate and biologic therapies,
Ahmed, S +4 more
core +2 more sources
Parabrachial nucleus circuit governs neuropathic pain-like behavior
The lateral parabrachial nucleus (LPBN) is known to relay noxious information to the amygdala for processing affective responses. However, it is unclear whether the LPBN actively processes neuropathic pain characterized by persistent hyperalgesia with ...
Li Sun +15 more
semanticscholar +1 more source
Diagnosis and management of trigeminal neuropathic pains [PDF]
Trigeminal neuropathic pains have presented diagnostic and therapeutic challenges to providers. In addition, knowledge of pathophysiology, current classification systems, taxonomy and phenotyping of these conditions are incomplete.
Napeñas, JJ, Zakrzewska, JM
core +1 more source
The neuropathic pain: An overview of the current treatment and future therapeutic approaches
Neuropathic pain is characterized by abnormal hypersensitivity to stimuli (hyperalgesia) and nociceptive responses to non-noxious stimuli (allodynia).
E. Cavalli +4 more
semanticscholar +1 more source

