Masahiro Hasegawa, Shine Tone, Yohei Naito, Akihiro Sudo Department of Orthopaedic Surgery, Mie University Graduate School of Medicine, Tsu City, Mie, 514-8507, JapanCorrespondence: Masahiro HasegawaDepartment of Orthopaedic Surgery, Mie University ...
Hasegawa M, Tone S, Naito Y, Sudo A
doaj
Cancer-related neuropathic pain at the outpatient pain clinic of the Clinical centre of Serbia: Cancer-related neuropathic pain [PDF]
Introduction: Neuropathic pain is defined as chronic pain caused by disease or lesion of somatosensory nerve system. Positive and negative signs and symptoms are manifestation of neuropathic pain.
Jovičić Jelena+3 more
doaj +1 more source
PainPoints: A Framework for Language-based Detection of Chronic Pain and Expert-Collaborative Text-Summarization [PDF]
Chronic pain is a pervasive disorder which is often very disabling and is associated with comorbidities such as depression and anxiety. Neuropathic Pain (NP) is a common sub-type which is often caused due to nerve damage and has a known pathophysiology.
arxiv
Expression profiles of TRPV1, TRPV4, TLR4 and ERK1/2 in the dorsal root ganglionic neurons of a cancer-induced neuropathy rat model [PDF]
Background: The spread of tumors through neural routes is common in several types of cancer in which patients suffer from a moderate-to-severe neuropathy, neural damage and a distorted quality of life. Here we aim to examine the expression profiles of transient receptor potential vanilloid 1 (TRPV1) and of transient receptor potential vanilloid 4 ...
arxiv +1 more source
Avoiding Catch-22:Validating the PainDETECT in a in a population of patients with chronic pain [PDF]
BACKGROUND: Neuropathic pain is defined as pain caused by a lesion or disease of the somatosensory nervous system and is a major therapeutic challenge. Several screening tools have been developed to help physicians detect patients with neuropathic pain ...
Bronkhorst, Ewald M+8 more
core +9 more sources
Diagnosis and management of trigeminal neuropathic pains [PDF]
Trigeminal neuropathic pains have presented diagnostic and therapeutic challenges to providers. In addition, knowledge of pathophysiology, current classification systems, taxonomy and phenotyping of these conditions are incomplete.
Napeñas, JJ, Zakrzewska, JM
core +1 more source
Objective:Low back pain (LBP) is the most common chronic pain disorder worldwide. Chronic LBP is a mixed pain syndrome associated with nociceptive and neuropathic pain mechanisms.
Bilge Kesikburun+4 more
doaj +1 more source
Neuropathic pain exerts a global burden caused by the lesions in the somatosensory nerve system, including the central and peripheral nervous systems. The mechanisms of nerve injury-induced neuropathic pain involve multiple mechanisms, various signaling ...
Ti-Yen Yeh+5 more
doaj +1 more source
Investigation of the Neuropathic Pain Caused by Syringomyelia Associated with Chiari I Malformation [PDF]
Study Design Retrospective cohort study. Purpose To investigate the correlation between the syrinx morphology and neuropathic pain caused by syringomyelia associated with Chiari I malformation.
Toshitaka Seki+5 more
doaj +1 more source
Immune or genetic-mediated disruption of CASPR2 causes pain hypersensitivity due to enhanced primary afferent excitability [PDF]
Human autoantibodies to contactin-associated protein-like 2 (CASPR2) are often associated with neuropathic pain, and CASPR2 mutations have been linked to autism spectrum disorders, in which sensory dysfunction is increasingly recognized.
Bennett, David L.+39 more
core +2 more sources