Results 51 to 60 of about 1,846,055 (403)

Neuropathic pain in leprosy: symptom profile characterization and comparison with neuropathic pain of other etiologies

open access: yesPAIN Reports, 2018
. Introduction:. Previous studies reported a high prevalence of neuropathic pain in leprosy, being especially present in “pharmacologically cured” patients.
Irina Raicher   +9 more
doaj   +1 more source

Antinociceptive activity of the S1P-receptor agonist FTY720 [PDF]

open access: yes, 2008
FTY720 is a novel immunosuppressive drug that inhibits the egress of lymphocytes from secondary lymphoid tissues and thymus. In its phosphorylated form FTY720 is a potent S1P receptor agonist.
Angioni, Carlo Federico   +8 more
core   +1 more source

Central Neuropathic Pain in a Patient with Multiple Sclerosis Treated Successfully with Topical Amitriptyline

open access: yesCase Reports in Medicine, 2012
Central neuropathic pain in patients with multiple sclerosis (MS) is a common debilitating symptom, which is mostly treated with tricyclic antidepressants or antiepileptics. Unfortunately, the use of these drugs is often limited due to adverse events. We
David J. Kopsky   +2 more
doaj   +1 more source

Oral ketamine vs placebo in patients with cancer-related neuropathic pain [PDF]

open access: yes, 2018
Ketamine hydrochloride is used as an adjuvant treatment for cancer-related neuropathic pain, but evidence of its effectiveness is limited.1 Findings of a large trial investigating the use of ketamine for general cancer pain were negative, but the ...
Fallon, Marie T.   +6 more
core   +4 more sources

Multicenter assessment of quantitative sensory testing (QST) for the detection of neuropathic-like pain responses using the topical capsaicin model [PDF]

open access: yes, 2018
Background: The use of quantitative sensory testing (QST) in multicenter studies has been quite limited, due in part to lack of standardized procedures among centers. Aim: The aim of this study was to assess the application of the capsaicin pain model
Bushnell, M. Catherine   +13 more
core   +1 more source

A modified score to identify and discriminate neuropathic pain: a study on the German version of the neuropathic pain symptom inventory (NPSI)

open access: yesBMC Neurology, 2011
Background Neuropathic pain must be correctly diagnosed for optimal treatment. The questionnaire named Neuropathic Pain Symptom Inventory (NPSI) was developed in its original French version to evaluate the different symptoms of neuropathic pain.
Lungenhausen Margitta   +5 more
doaj   +1 more source

Use of the painDETECT tool in rheumatoid arthritis suggests neuropathic and sensitization components in pain reporting. [PDF]

open access: yes, 2014
Rheumatoid arthritis (RA) is an inflammatory autoimmune condition typified by systemic inflammation targeted toward synovial joints. Inhibition of proinflammatory networks by disease-modifying antirheumatic drugs, eg, methotrexate and biologic therapies,
Ahmed, S   +4 more
core   +2 more sources

Parabrachial nucleus circuit governs neuropathic pain-like behavior

open access: yesNature Communications, 2020
The lateral parabrachial nucleus (LPBN) is known to relay noxious information to the amygdala for processing affective responses. However, it is unclear whether the LPBN actively processes neuropathic pain characterized by persistent hyperalgesia with ...
Li Sun   +15 more
semanticscholar   +1 more source

Diagnosis and management of trigeminal neuropathic pains [PDF]

open access: yes, 2011
Trigeminal neuropathic pains have presented diagnostic and therapeutic challenges to providers. In addition, knowledge of pathophysiology, current classification systems, taxonomy and phenotyping of these conditions are incomplete.
Napeñas, JJ, Zakrzewska, JM
core   +1 more source

The neuropathic pain: An overview of the current treatment and future therapeutic approaches

open access: yesInternational Journal of Immunopathology and Pharmacology, 2019
Neuropathic pain is characterized by abnormal hypersensitivity to stimuli (hyperalgesia) and nociceptive responses to non-noxious stimuli (allodynia).
E. Cavalli   +4 more
semanticscholar   +1 more source

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