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Role of plasma neuropeptide Y in acute myocardial infarction: a case-control study [PDF]

open access: yesBMC Cardiovascular Disorders
Background As neuropeptide Y is associated with endothelial dysfunction, this study explored the relationship between neuropeptide Y and acute myocardial infarction. Methods We included 128 acute myocardial infarction cases and 62 controls.
Yan-li Zheng   +7 more
doaj   +2 more sources

Neuropeptide Y in first-episode schizophrenia: is there any sex differences in the pathogeneses of schizophrenia? [PDF]

open access: yesFrontiers in Psychiatry
ObjectiveThis study investigated relationships between Neuropeptide Y levels and severity of psychiatric symptoms in first-episode schizophrenia patients, and explore the sexual heterogeneity in them.MethodsWe recruited 115 first-episode schizophrenia ...
Jia-Qi Song   +5 more
doaj   +2 more sources

Evolution of neuropeptide Y/RFamide-like receptors in nematodes [PDF]

open access: yesHeliyon
The Neuropeptide Y/RFamide-like receptors belong to the Rhodopsin-like G protein-coupled receptors G protein-coupled receptors (GPCRs) and are involved in functions such as locomotion, feeding and reproduction.
Franziska Reinhardt   +3 more
doaj   +2 more sources

Intermittent Fasting Targets Osteocyte Neuropeptide Y to Relieve Osteoarthritis [PDF]

open access: yesAdvanced Science
Osteoarthritis is a highly prevalent progressive joint disease that still requires an optimal therapeutic approach. Intermittent fasting is an attractive dieting strategy for improving health.
Yu‐Xuan Qian   +20 more
doaj   +2 more sources

Overexpression of neuropeptide Y decreases responsiveness to neuropeptide Y [PDF]

open access: yesNeuropeptides, 2020
Neuropeptide Y (NPY) is an endogenous neuropeptide that is abundantly expressed in the central nervous system. NPY is involved in various neurological processes and neuropsychiatric disorders, including fear learning and anxiety disorders. Reduced levels of NPY are reported in Post-Traumatic Stress Disorder (PTSD) patients, and NPY has been proposed as
Katelynn M, Corder   +5 more
openaire   +2 more sources

The Bidirectional Relationship of NPY and Mitochondria in Energy Balance Regulation

open access: yesBiomedicines, 2023
Energy balance is regulated by several hormones and peptides, and neuropeptide Y is one of the most crucial in feeding and energy expenditure control. NPY is regulated by a series of peripheral nervous and humoral signals that are responsive to nutrient ...
Diana Sousa   +3 more
doaj   +1 more source

Neuropeptide Y/Y5 Receptor Pathway Stimulates Neuroblastoma Cell Motility Through RhoA Activation

open access: yesFrontiers in Cell and Developmental Biology, 2021
Neuropeptide Y (NPY) has been implicated in the regulation of cellular motility under various physiological and pathological conditions, including cancer dissemination. Yet, the exact signaling pathways leading to these effects remain unknown.
Nouran Abualsaud   +9 more
doaj   +1 more source

Neuropeptide Y regulates proliferation and apoptosis in granulosa cells in a follicular stage-dependent manner

open access: yesJournal of Ovarian Research, 2020
Background The complex regulatory mechanism involved in ovarian follicular development is not completely understood. Neuronal neuropeptide Y (NPY) is involved in the regulation of feeding behavior, energy homeostasis, and reproduction behavior, while its
Yoko Urata   +4 more
doaj   +1 more source

Unusually persistent Gαi-signaling of the neuropeptide Y2 receptor depletes cellular Gi/o pools and leads to a Gi-refractory state

open access: yesCell Communication and Signaling, 2020
Background A sensitive balance between receptor activation and desensitization is crucial for cellular homeostasis. Like many other GPCR, the human neuropeptide Y2 receptor (hY2R) undergoes ligand dependent activation and internalization into ...
Isabelle Ziffert   +4 more
doaj   +1 more source

Neuropeptide Y directly reduced apoptosis of granulosa cells, and the expression of NPY and its receptors in PCOS subjects

open access: yesJournal of Ovarian Research, 2023
Background Most women with anovulatory infertility show polycystic ovarian syndrome (PCOS), and androgen excess is known as a key factor involved in pathogenicity of PCOS.
Yoko Urata   +7 more
doaj   +1 more source

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