Conserved context‐dependent cis‐regulatory elements act as a major reservoir of disease‐associated polymorphisms in the human genome and are also affected by epigenetic change. This ‘state‐of‐the‐art’ review explores the latest developments in studying these enigmatic elements and how the effects of disease‐associated polymorphisms and environmentally ...
Andrew McEwan+5 more
wiley +1 more source
Effects of neuropeptide Y and agonists selective for neuropeptide Y receptor sub‐types on arterioles of the guinea‐pig small intestine and the rat brain [PDF]
Jun Xia, T O Neild, Neela Kotecha
openalex +1 more source
Can serum neuropeptide levels help diagnose pediatric migraine? A prospective case–control study
Abstract Objective The objective of this study was to examine the serum levels of vasoactive neuropeptides (calcitonin gene‐related peptide [CGRP], pituitary adenylate cyclase‐activating peptide‐38 [PACAP‐38], substance P [SP], and vasoactive intestinal peptide [VIP], which have been linked to the pathophysiology of migraine in adults) in pediatric ...
Sibğatullah Ali Orak+8 more
wiley +1 more source
Presynaptic action of neuropeptide Y in area CA1 of the rat hippocampal slice.
William F. Colmers+2 more
openalex +2 more sources
Functional effects and ligand binding of chimeric galanin‐neuropeptide Y (NPY) peptides on NPY and galanin receptor types [PDF]
Ulrika Kahl+3 more
openalex +1 more source
Abstract Objectives/Background This study was undertaken to assess the therapeutic efficacy of galcanezumab in preclinical models of migraine and cluster headache and to determine potential shared trigeminovascular mechanisms of action. Galcanezumab is a humanized monoclonal antibody that binds to the neuropeptide calcitonin gene‐related peptide ...
Marta Vila‐Pueyo+3 more
wiley +1 more source
Binding of Monoiodinated Neuropeptide Y to Hippocampal Membranes and Human Neuroblastoma Cell Lines
Søren P. Sheikh+3 more
openalex +1 more source
Presynaptic inhibition by neuropeptide Y in rat hippocampal slice in vitro is mediated by a Y2 receptor [PDF]
William F. Colmers+4 more
openalex +1 more source
Feeding inhibition by neuropeptide Y [PDF]
L. Arthur Campfield+4 more
openaire +3 more sources
Functional sympatholysis of neuropeptide Y-mediated vasoconstriction in humans. [PDF]
Wakeham DJ+6 more
europepmc +1 more source