Results 11 to 20 of about 9,276,761 (294)
A Promising Therapeutic Target for Metabolic Diseases: Neuropeptide Y Receptors in Humans
Cellular Physiology and Biochemistry, 2017 Human neuropeptide Y (hNPY) is one of the most widely expressed neurotransmitters in the human central and peripheral nervous systems. It consists of 36 highly conserved amino acid residues, and was first isolated from the porcine hypothalamus in 1982 ...
Min Yi +6 more
doaj +2 more sources
Structural basis of neuropeptide Y signaling through Y1 receptor
Nature Communications, 2022 Neuropeptide Y (NPY) is highly abundant in the brain and involved in various physiological processes related to food intake and anxiety, as well as human diseases such as obesity and cancer.
Chaehee Park +12 more
semanticscholar +1 more source
Hunger enhances food odor attraction through a Neuropeptide Y spotlight
Nature, 2021 Internal state controls olfaction through poorly understood mechanisms. Odours that represent food, mates, competitors and predators activate parallel neural circuits that may be flexibly shaped by physiological need to alter behavioural outcome1.
Nao Horio, S. Liberles
semanticscholar +1 more source
Frontiers in Cell and Developmental Biology, 2021 Through the past decade of research, the pathogenic mechanisms underlying metabolic syndrome have been suggested to involve not only the peripheral tissues, but also central metabolic regulation imbalances.
Yinqiong Huang, Xiahong Lin, Shu Lin
semanticscholar +1 more source
The Roles of Neuropeptide Y (Npy) and Peptide YY (Pyy) in Teleost Food Intake: A Mini Review
Life, 2021 Neuropeptide Y family (NPY) is a potent orexigenic peptide and pancreatic polypeptide family comprising neuropeptide Y (Npy), peptide YYa (Pyya), and peptide YYb (Pyyb), which was previously known as peptide Y (PY), and tetrapod pancreatic polypeptide ...
D. Assan +5 more
semanticscholar +1 more source
The Bidirectional Relationship of NPY and Mitochondria in Energy Balance Regulation
Biomedicines, 2023 Energy balance is regulated by several hormones and peptides, and neuropeptide Y is one of the most crucial in feeding and energy expenditure control. NPY is regulated by a series of peripheral nervous and humoral signals that are responsive to nutrient ...
Diana Sousa +3 more
doaj +1 more source
Neuropeptide Y/Y5 Receptor Pathway Stimulates Neuroblastoma Cell Motility Through RhoA Activation
Frontiers in Cell and Developmental Biology, 2021 Neuropeptide Y (NPY) has been implicated in the regulation of cellular motility under various physiological and pathological conditions, including cancer dissemination. Yet, the exact signaling pathways leading to these effects remain unknown.
Nouran Abualsaud +9 more
doaj +1 more source
Neuropeptide Y Is an Immunomodulatory Factor: Direct and Indirect
Frontiers in Immunology, 2020 Neuropeptide Y (NPY), which is widely distributed in the nervous system, is involved in regulating a variety of biological processes, including food intake, energy metabolism, and emotional expression.
Wei-can Chen +5 more
semanticscholar +1 more source
Journal of Ovarian Research, 2020 Background The complex regulatory mechanism involved in ovarian follicular development is not completely understood. Neuronal neuropeptide Y (NPY) is involved in the regulation of feeding behavior, energy homeostasis, and reproduction behavior, while its
Yoko Urata +4 more
doaj +1 more source
Cell Communication and Signaling, 2020 Background A sensitive balance between receptor activation and desensitization is crucial for cellular homeostasis. Like many other GPCR, the human neuropeptide Y2 receptor (hY2R) undergoes ligand dependent activation and internalization into ...
Isabelle Ziffert +4 more
doaj +1 more source