Results 51 to 60 of about 9,276,761 (294)

Role of plasma neuropeptide Y in acute myocardial infarction: a case-control study

open access: yesBMC Cardiovascular Disorders
Background As neuropeptide Y is associated with endothelial dysfunction, this study explored the relationship between neuropeptide Y and acute myocardial infarction. Methods We included 128 acute myocardial infarction cases and 62 controls.
Yan-li Zheng   +7 more
doaj   +1 more source

Regulation of Feeding and Metabolism by Neuropeptide F and Short Neuropeptide F in Invertebrates

open access: yesFrontiers in Endocrinology, 2019
Numerous neuropeptide systems have been implicated to coordinately control energy homeostasis, both centrally and peripherally. However, the vertebrate neuropeptide Y (NPY) system has emerged as the best described one regarding this biological process ...
Melissa Fadda   +5 more
doaj   +1 more source

Role of Zip1 in the regulation of NPY expression by MLT to promote fracture healing in rats

open access: yesEuropean Journal of Histochemistry, 2020
Our previous study documented that melatonin (MLT) induced the osteogenic differentiation of mesenchymal stem cells (MSCs) and promoted the healing of femoral fractures in rats via the neuropeptide Y (NPY)/neuropeptide Y1 receptor (NPY1R) signaling ...
Junjun Shang   +6 more
doaj   +1 more source

Comparative study of the effects of the three kinds of Kampo-hozai: Ninjinyoeito, Hochuekkito, and Juzentaihoto on anxious and low sociability behavior using NPY-knockout zebrafish

open access: yesFrontiers in Pharmacology, 2023
Ninjinyoeito, Hochuekkito, and Juzentaihoto are the three types of Kampo-hozai used to support the treatment of various diseases by energizing patients through improved mental health.
Momoko Kawabe   +6 more
doaj   +1 more source

Oxytocin‐Mediate Modulation of Splenic Immunosuppression in Chronic Social Stress Through Neuroendocrine Pathways

open access: yesAdvanced Science, EarlyView.
Chronic social stress elevates oxytocin levels, leading to immunosuppression by enhancing regulatory T‐cell activity and promoting anti‐inflammatory macrophage polarization in the spleen. Blocking oxytocin signaling reverses these effects but worsens stress‐induced behavioral disorders and reduces survival rates. This highlights oxytocin's dual role in
Yi‐Shu Zhang   +5 more
wiley   +1 more source

In Vivo Cytosolic Delivery of Biomolecules into Neurons for Super‐Resolution Imaging and Genome Modification

open access: yesAdvanced Science, EarlyView.
The N1 peptide specifically targets neurons, enabling cytosolic delivery of fluorescent dyes and proteins for super‐resolution imaging and functional genetic modification. Abstract Efficient delivery of biomolecules into neurons has significant impacts on therapeutic applications in the central nervous system (CNS) and fundamental neuroscience research.
Xiaoqian Ge   +16 more
wiley   +1 more source

Pharmacological and functional similarities of the human neuropeptide Y system in C. elegans challenges phylogenetic views on the FLP/NPR system

open access: yesCell Communication and Signaling, 2019
Background The neuropeptide Y system affects various processes, among others food intake, and is frequently discussed in the context of targeting obesity. Studies in model organisms are indispensable to enable molecular studies in a physiological context.
Miron Mikhailowitsch Gershkovich   +3 more
doaj   +1 more source

MAGEA6 Engages a YY1‐Dependent Transcription to Dictate Perineural Invasion in Colorectal Cancer

open access: yesAdvanced Science, EarlyView.
This study investigates the role of MAGEA6 in perineural invasion (PNI) in colorectal cancer (CRC). MAGEA6 promotes CRC invasiveness by inhibiting YY1 ubiquitination, enhancing CXCL1 secretion, and recruiting Schwann cells. These findings highlight the potential of targeting the MAGEA6/YY1/CXCL1 axis for therapeutic strategies against PNI and tumor ...
Hao Wang   +9 more
wiley   +1 more source

Antisense mRNA for NPY-Y1 receptor in the medial preoptic area increases prolactin secretion

open access: yesBrazilian Journal of Medical and Biological Research, 1999
We investigated the participation of neuropeptide Y-Y1 receptors within the medial preoptic area in luteinizing hormone, follicle-stimulating hormone and prolactin release.
N.A. Silveira, C.R. Franci
doaj   +1 more source

Regulation of neuropeptide Y in body microenvironments and its potential application in therapies: a review

open access: yesCell & Bioscience, 2021
Neuropeptide Y (NPY), one of the most abundant neuropeptides in the body, is widely expressed in the central and peripheral nervous systems and acts on the cardiovascular, digestive, endocrine, and nervous systems.
Yan Zhang   +6 more
doaj   +1 more source

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