Results 1 to 10 of about 212,465 (393)
Neuropeptide Y receptor in the rat brain [PDF]
European Journal of Biochemistry, 1984 The specific binding of the chloramine-T iodinated neuropeptide Y (125I-NPY) to membranes from rat cerebral cortex was investigated using equilibrium binding and kinetic methods. The equilibrium binding of 125I-NPY at 37 degrees C was characterized by a Kd value of 0.38 nM. The receptor densities in the cerebral cortex, hypothalamus and cerebellum were
Viktor Mutt +3 more
semanticscholar +6 more sources
New antagonist agents of neuropeptide y receptors [PDF]
Química Nova, 2000 0 ...
Aldana, Ignacio +8 more
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Cloning and Expression of a Novel Neuropeptide Y Receptor [PDF]
Journal of Biological Chemistry, 1996 The neuropeptide Y family of peptides, which includes neuropeptide Y (NPY), peptide YY (PYY), and pancreatic polypeptide (PP), are found in the central and peripheral nervous system and display a wide array of biological activities. These actions are believed to be mediated through pharmacologically distinct G protein-coupled receptors, and, to date ...
David H. Weinberg +12 more
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Characterization of vascular neuropeptide Y receptors [PDF]
British Journal of Pharmacology, 1992 In the present study we compared neuropeptide Y (NPY) and NPY‐related analogues for their ability to activate or bind to vascular NPY receptors in four experimental set‐ups. Previous results have suggested the existence of different receptor subtypes, Y1 receptors requiring full‐length NPY (1–36) or [Pro34]‐NPY, and Y2 receptors recognizing also N ...
Rolf Håkanson +5 more
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Ligands of the neuropeptide Y Y2 receptor [PDF]
Bioorganic & Medicinal Chemistry Letters, 2014 AbstractReview: 64 refs.
Gopi Kumar Mittapalli, Edward Roberts
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Synthesis of receptor antagonists of neuropeptide Y. [PDF]
Proceedings of the National Academy of Sciences, 1992 We report the synthesis of receptor antagonists of neuropeptide Y (NPY) by a strategy based on synthesis of mixtures of analogs and the subsequent isolation and identification of receptor antagonists from these mixtures. After screening a series of mixtures of NPY analogs by using an NPY antagonist assay, two potent receptor antagonists, designated PYX-
Meikyo Shimizu +2 more
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NPY1R (neuropeptide Y receptor Y1) [PDF]
Atlas of Genetics and Cytogenetics in Oncology and Haematology, 2011 Review on NPY1R (neuropeptide Y receptor Y1), with data on DNA, on the protein encoded, and where the gene is implicated.
M. Ruscica +3 more
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Y1 and Y2 receptors for neuropeptide Y [PDF]
FEBS Letters, 1989 By using monoiodinated radioligands of both intact neuropeptide Y (NPY) and of a long C‐terminal fragment, NPY13–36, two subtypes of binding sites, which differ in affinity and specificity, have been characterized. The Y1 type of binding site, characterized on a human neuroblastoma cell line, MC‐IXC, and a rat pheochromocytoma cell line, PC‐12, binds ...
Thue W. Schwartz +2 more
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Neuropeptide Y Y2 receptor in health and disease [PDF]
British Journal of Pharmacology, 2008 British Journal of Pharmacology (2008) 155, 1307; doi:10.1038/bjp.2008 ...
Ambikaipakan Balasubramaniam +1 more
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Influence of Neuropeptide Y and Neuropeptide Y 2 Receptor Variants in Acute Coronary Syndrome [PDF]
International Journal of Cardiovascular Sciences, 2021 Abstract Background The neuropeptide Y (NPY) is one of the most abundant neurotransmitters in the nervous system. NPY acts as a potent stimulator of angiogenesis, inflammation, and adipogenesis, through the NPY 2 receptor (NPY2R). Changes in the NPY signaling pathway have been linked to Acute Coronary Syndrome (ACS).
Fábia C. S. Soares +13 more
openaire +4 more sources