Results 91 to 100 of about 212,465 (393)

The Lymnaea Cardioexcitatory Peptide (LyCEP) Receptor: A G-Protein–Coupled Receptor for a Novel Member of the RFamide Neuropeptide Family [PDF]

, 1998
A novel G-protein–coupled receptor (GRL106) resembling neuropeptide Y and tachykinin receptors was cloned from the molluscLymnaea stagnalis. Application of a peptide extract from the Lymnaea brain to Xenopus oocytes expressing GRL106 activated a calcium ...
Burke, Julian F, Cox, Kingsley J A, Geraerts, Wijnand P M, Hermann, Petra M, Knol, Jaco C, Meyerhof, Wolfgang, Planta, Rudi J, Richter, Dietmar, Smit, August B, Tensen, Cornelius P, van der Schors, Roel C, van Heerikhuizen, Harm, van Minnen, Jan, Vreugdenhil, Erno   +13 more
core   +7 more sources

Peripherally Administered Y2-Receptor Antagonist BIIE0246 Prevents Diet-Induced Obesity in Mice With Excess Neuropeptide Y, but Enhances Obesity in Control Mice

Frontiers in Pharmacology, 2018
Neuropeptide Y (NPY) plays an important role in the regulation of energy homeostasis in the level of central and sympathetic nervous systems (SNSs).
Liisa Ailanen, Liisa Ailanen, Laura H. Vähätalo, Henriikka Salomäki-Myftari, Henriikka Salomäki-Myftari, Satu Mäkelä, Wendy Orpana, Suvi T. Ruohonen, Eriika Savontaus, Eriika Savontaus   +9 more
doaj   +1 more source

Short communication: expression of peptide YY, proglucagon, neuropeptide Y receptor Y2, and glucagon-like peptide-1 receptor in bovine peripheral tissues.

Journal of Dairy Science, 2012
The role of distal gut signals in control of feed intake and metabolism in cattle has received scant attention. Peptide YY (PYY) and glucagon-like peptide-1, which are secreted from enteroendocrine cells of the distal gut in monogastrics have several ...
A. Pezeshki, G. Muench, P. Chelikani
semanticscholar   +1 more source

Chicken neuropeptide Y-family receptor Y4: a receptor with equal affinity for pancreatic polypeptide, neuropeptide Y and peptide YY [PDF]

Journal of Molecular Endocrinology, 2002
Within the neuropeptide Y (NPY) family of peptides, pancreatic polypeptide is the most divergent across species. It differs in 20 of 36 positions between human and chicken. In mammals, it binds primarily to the Y4 receptor, to which NPY and peptide YY (PYY) bind with lower affinities.
Ingrid Lundell, Dan Larhammar, Timothy Boswell   +2 more
openaire   +4 more sources

3‐Year Outcomes of Temperature‐Controlled Radiofrequency Ablation of the Posterior Nasal Nerve in Patients With Chronic Rhinitis

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Temperature‐controlled radiofrequency (TCRF) ablation of the posterior nasal nerve has been shown to improve chronic rhinitis (CR) symptoms and quality of life (QoL). This study assesses the durability of TCRF's effectiveness and safety 3 years post‐procedure in patients with perennial allergic CR and nonallergic CR.
J. Pablo Stolovitzky, Randall A. Ow, Stacey L. Silvers, Bobby A. Tajudeen, Chad M. McDuffie, Marc Dean, Ahmad R. Sedaghat, Katie Phillips, Masayoshi Takashima   +8 more
wiley   +1 more source

An opioid-like system regulating feeding behavior in C. elegans [PDF]

, 2015
Neuropeptides are essential for the regulation of appetite. Here we show that neuropeptides could regulate feeding in mutants that lack neurotransmission from the motor neurons that stimulate feeding muscles. We identified nlp-24 by an RNAi screen of 115
Artyukhin, Alexander B., Avery, Leon, Cheong, Mi Cheong, You, Yong-Jai   +3 more
core   +3 more sources

Neuropeptide Y receptor binding sites in rat brain: differential autoradiographic localizations with 125I-peptide YY and 125I- neuropeptide Y imply receptor heterogeneity

Journal of Neuroscience, 1989
Neuropeptide Y (NPY) receptor binding sites have been localized in the rat brain by in vitro autoradiography using picomolar concentrations of both 125I-NPY and 125I-peptide YY (PYY) and new evidence provided for differentially localized receptor ...
D. Lynch, M. Walker, R.J. Miller, S. Snyder   +3 more
semanticscholar   +1 more source

Targeting Neuropeptide Receptors for Cancer Imaging and Therapy: Perspectives with Bombesin, Neurotensin, and Neuropeptide-Y Receptors [PDF]

Journal of Nuclear Medicine, 2014
Receptors for some regulatory peptides are highly expressed in tumors. Selective radiolabeled peptides can bind with high affinity and specificity to these receptors and exhibit favorable pharmacologic and pharmacokinetic properties, making them suitable agents for imaging or targeted therapy.
Philippe Fernandez, Elif Hindié, Elif Hindié, Michèle Allard, Anil K. Mishra, Raunak Varshney, Clément Morgat   +6 more
openaire   +3 more sources

Evolution of the neuropeptide Y receptor family: gene and chromosome duplications deduced from the cloning and mapping of the five receptor subtype genes in pig.

Genome Research, 2000
Neuropeptide Y (NPY) receptors mediate a variety of physiological responses including feeding and vasoconstriction. To investigate the evolutionary events that have generated this receptor family, we have sequenced and determined the chromosomal ...
A. Wraith, A. Törnsten, P. Chardon, Ingrid Harbitz, B. P. Chowdhary, Leif Andersson, Lars-Gustav Lundin, Dan Larhammar   +7 more
semanticscholar   +1 more source

Serotonin mediated changes in corticotropin releasing factor mRNA expression and feeding behavior isolated to the hypothalamic paraventricular nuclei [PDF]

, 2011
Fenfluramine reduces hunger and promotes body weight loss by increasing central serotonin (5-HT) signaling. More recently, neuropeptides have been linked to the regulation of feeding behavior, metabolism and body weight.
Boisvert, Joanne P, Boschuetz, Tyler J., Choi, Sujean, Mueller, Christopher R, Resch, Jon M   +4 more
core   +2 more sources