Results 111 to 120 of about 213,878 (394)

Molecular mechanism of prolactin-releasing peptide recognition and signaling via its G protein-coupled receptor

open access: yesCell Discovery
Prolactin-releasing peptide (PrRP) is an RF-amide neuropeptide that binds and activates its cognate G protein-coupled receptor, prolactin-releasing peptide receptor (PrRPR), also known as GPR10.
Yang Li   +8 more
doaj   +1 more source

Calcitonin receptor-like receptor is expressed on gastrointestinal immune cells [PDF]

open access: yes, 2002
Background/Aims: Pharmacological and morphological studies suggest that the gut mucosal immune system and local neuropeptide-containing neurones interact.
Göke, B.   +5 more
core   +1 more source

Early vertebrate chromosome duplications and the evolution of the neuropeptide Y receptor gene regions

open access: yesBMC Evolutionary Biology, 2008
BackgroundOne of the many gene families that expanded in early vertebrate evolution is the neuropeptide (NPY) receptor family of G-protein coupled receptors.
T. Larsson   +6 more
semanticscholar   +1 more source

Intestinal Barrier Glycosylation for Gut Physiology and Pathology

open access: yesBarrier Immunity, EarlyView.
ABSTRACT The intestinal barrier is a selective structure that safeguards the body from external threats while permitting nutrient absorption and immune surveillance. It consists of the outer mucus layer, the intermediate layer of intestinal epithelial cells (IECs), and the inner layer of immune cells. The proteins in the mucus layer and within IECs are
Girak Kim, Deji Ye, Yikun Yao, Chuan Wu
wiley   +1 more source

Research on Correlation Between Psychological Factors, Mast Cells, and PAR-2 Signal Pathway in Irritable Bowel syndrome

open access: yesJournal of Inflammation Research, 2021
Guanqun Chao,1 Zhaojun Wang,2 Shuo Zhang3 1Department of General Practice, Sir Run Run Shaw Hospital, Zhejiang University, Hangzhou, People’s Republic of China; 2The First Clinical Medical College of Zhejiang Chinese Medicine University, Hangzhou ...
Chao G, Wang Z, Zhang S
doaj  

PACAP and migraine headache: immunomodulation of neural circuits in autonomic ganglia and brain parenchyma. [PDF]

open access: yes, 2018
The discovery that intravenous (IV) infusions of the neuropeptide PACAP-38 (pituitary adenylyl cyclase activating peptide-38) induced delayed migraine-like headaches in a large majority of migraine patients has resulted in considerable excitement in ...
Akerman, Simon   +2 more
core   +2 more sources

Gut‐microbiota‐brain Axis and post‐traumatic epilepsy

open access: yesEpilepsia Open, EarlyView.
Abstract There has been growing evidence that perturbations in gut‐microbiota‐brain axis (GMBA) are involved in mechanisms of chronic sequelae of traumatic brain injury (TBI). This review discusses the connection between GMBA and post‐traumatic epilepsy (PTE), the latter being a common outcome of TBI.
Andrey Mazarati
wiley   +1 more source

A Promising Therapeutic Target for Metabolic Diseases: Neuropeptide Y Receptors in Humans

open access: yesCellular Physiology and Biochemistry, 2017
Human neuropeptide Y (hNPY) is one of the most widely expressed neurotransmitters in the human central and peripheral nervous systems. It consists of 36 highly conserved amino acid residues, and was first isolated from the porcine hypothalamus in 1982 ...
Min Yi   +6 more
doaj   +1 more source

Insulin signal transduction mediates ethanol-induced feeding dysfunction in a fly model of Fetal Alcohol Spectrum Disorder [PDF]

open access: yes, 2019
Fetal alcohol spectrum disorder (FASD) is the leading cause of congenital intellectual disabilities in the Western World, with a worldwide prevalence of 2-11% of all births.
Matsubara, Manae
core   +1 more source

A role of corazonin receptor in larval-pupal transition and pupariation in the oriental fruit fly Bactrocera dorsalis (Hendel) (Diptera: Tephritidae) [PDF]

open access: yes, 2017
Corazonin (Crz) is a neuropeptide hormone, but also a neuropeptide modulator that is internally released within the CNS, and it has a widespread distribution in insects with diverse physiological functions.
Chen, Er-Hu   +7 more
core   +2 more sources

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