Results 151 to 160 of about 47,789 (213)

Fine-Tuning of the Neuropeptide Y1 G Protein-Coupled Receptor by the Tryptophan<sup>6.48</sup> "Toggle Switch". [PDF]

open access: yesJ Am Chem Soc
Voitel M   +7 more
europepmc   +1 more source

Effect of Centrally Administered Neuropeptide Y and α-Melanocyte-stimulating Hormone on Water Intake in Chicks. [PDF]

open access: yesJ Poult Sci
Dialoke NG   +7 more
europepmc   +1 more source

Vasoactive neuropeptide dysregulation: A novel mechanism of microvascular dysfunction in vascular cognitive impairment. [PDF]

open access: yesAlzheimers Dement
Tambo W   +9 more
europepmc   +1 more source

Neuropeptide Y receptor subtypes

Life Sciences, 1995
Neuropeptide Y (NPY) is an amidated 36-amino acid peptide with a wide distribution in the central and peripheral nervous system. It can evoke numerous physiological responses by activating specific receptors. Studies using NPY analogs in various model systems and cell types demonstrate different orders of ligand potency and receptor binding affinity ...
C P, Wan, B H, Lau
openaire   +2 more sources

Dihydropyridine Neuropeptide Y Y1 Receptor Antagonists

Bioorganic & Medicinal Chemistry Letters, 2002
Dihydropyridine 5a was found to be an inhibitor of neuropeptide Y(1) binding in a high throughput (125)I-PYY screening assay. Structure-activity studies around certain portions of the dihydropyridine chemotype identified BMS-193885 (6e) as a potent and selective Y(1) receptor antagonist.
Graham S, Poindexter   +13 more
openaire   +2 more sources

Neuropeptide Y receptor antagonists in obesity

Expert Opinion on Investigational Drugs, 1997
Neuropeptide Y (NPY) is a 36 amino acid amidated peptide with high sequence homology to the endocrine peptides, peptide YY (PYY) and pancreatic polypeptide (PP). They appear to interact with a family of receptors that possess high affinity for one or more of these peptides.
D R, Gehlert, P A, Hipskind
openaire   +2 more sources

Home - About - Disclaimer - Privacy