Results 161 to 170 of about 213,878 (394)

Neuropeptide Y is important for basal and seizure-induced precursor cell proliferation in the hippocampus

Neurobiology of Disease, 2007
We have shown that neuropeptide Y (NPY) regulates neurogenesis in the normal dentate gyrus (DG) via Y1 receptors (Howell, O.W., Scharfman, H.E., Herzog, H., Sundstrom, L.E., Beck-Sickinger, A. and Gray, W.P.
Owain W. Howell, Sharmalene Silva, Helen E. Scharfman, Alexander A. Sosunov, Malik Zaben, Anan Shatya, Guy Mckhann, II, Herbert Herzog, Alexandra Laskowski, William P. Gray   +9 more
doaj  

Association between neuropeptide Y receptor Y2 promoter variant rs6857715 and major depressive disorder

Psychiatric Genetics, 2017
J. Treutlein, J. Strohmaier, J. Frank, S. Witt, L. Rietschel, A. Forstner, M. Lang, F. Degenhardt, H. Dukal, S. Herms, F. Streit, P. Hoffmann, S. Cichon, M. Nöthen, M. Rietschel   +14 more
semanticscholar   +1 more source

Resting behaviour as a target for innovative mosquito control strategies

Methods in Ecology and Evolution, EarlyView.
Abstract This work reviews and discusses how a deeper knowledge of mosquito time‐allocation, particularly resting periods, can enhance the effectiveness and deployment of classical vector control tools. As more high‐resolution data are gathered by novel tracking devices, follow‐up questions investigating mosquito behaviour are likely to arise ...
David Jimenez‐Vallejo, Gabriela Gonzalez‐Olvera, Arty Makagon, Matt Neligeorge, Azael Che‐Mendoza, Pablo Manrique‐Saide, Gonzalo M. Vazquez‐Prokopec   +6 more
wiley   +1 more source

Structural basis for recognition of 26RFa by the pyroglutamylated RFamide peptide receptor

Cell Discovery
The neuropeptide 26RFa, a member of the RF-amide peptide family, activates the pyroglutamylated RF-amide peptide receptor (QRFPR), a class A GPCR. The 26RFa/QRFPR system plays critical roles in energy homeostasis, making QRFPR an attractive drug target ...
Sanshan Jin, Shimeng Guo, Youwei Xu, Xin Li, Canrong Wu, Xinheng He, Benxun Pan, Wenwen Xin, Heng Zhang, Wen Hu, Yuling Yin, Tianwei Zhang, Kai Wu, Qingning Yuan, H. Eric Xu, Xin Xie, Yi Jiang   +16 more
doaj   +1 more source

Phase Shifting of Circadian Rhythms and Depression of Neuronal Activity in the Rat Suprachiasmatic Nucleus by Neuropeptide Y: Mediation by Different Receptor Subtypes [PDF]

, 1998
Valentin K. Gribkoff, Rick L. Pieschl, Todd Wisialowski, Anthony N. van den Pol, Frank D. Yocca   +4 more
openalex   +1 more source

Accumulation of GSK‐3β in Interneurons Impairs Adult Hippocampal Neurogenesis by Inhibiting GABAergic Transmission

Aging Cell, EarlyView.
Overexpression of GSK‐3β in DG GABAergic neurons impairs neurogenesis by reducing GABA release, which can be reversed by enhancing GABAergic transmission. ABSTRACT The activation of glycogen synthase kinase 3β (GSK‐3β) and the deterioration of spatial memory represent prominent pathological and clinical manifestations of Alzheimer's disease (AD ...
Fei Liu, Jiu‐Jing Cui, Xiao‐Lin Li, Zeng‐Min Zhang, Shao‐Hua Liang, Yi Sun, Jing‐Min Li, Hong‐Lin Qu, Jing Ye, Qi‐Peng Guo, Quan Zheng, Yong‐Feng Liu   +11 more
wiley   +1 more source

The Dynamics of the Neuropeptide Y Receptor Type 1 Investigated by Solid-State NMR and Molecular Dynamics Simulation. [PDF]

Molecules, 2020
Vogel A, Bosse M, Gauglitz M, Wistuba S, Schmidt P, Kaiser A, Gurevich VV, Beck-Sickinger AG, Hildebrand PW, Huster D.   +9 more
europepmc   +1 more source

Role of G-protein βγ subunits in the augmentation of P2Y2 (P2U) receptor-stimulated responses by neuropeptide Y Y1 Gi/o-coupled receptors [PDF]

, 1997
A. Lisa SELBIE, Natalie King, John M. Dickenson, Stephen J. Hill   +3 more
openalex   +1 more source

Senescence Alters Antimicrobial Peptide Expression and Induces Amyloid‐β Production in Retinal Pigment Epithelial Cells

Aging Cell, EarlyView.
Healthy RPE cells produce AMPs and AMP precursors, including amyloid precursor protein (APP) and chemerin, and protect the neuroretina from blood‐borne pathogens and maintain homeostasis. When RPE cells undergo senescence, the antibacterial activity declines, and APP undergoes amylogenesis, leading to Aβ deposition.
Jian Liu, Caijiao Yi, Jinyan Qi, Xuexue Cui, Xiangling Yuan, Wen Deng, Mei Chen, Heping Xu   +7 more
wiley   +1 more source

Neuropeptide Y Y2 receptors in hypothalamic neuroendocrine areas are up-regulated by estradiol and decreased by progesterone cotreatment in the ovariectomized rat. [PDF]

, 1996
Steven L. Parker, Brittany L. Carroll, S. P. Kalra, S. St‐Pierre, Alain Fournier, William R. Crowley   +5 more
openalex   +1 more source