Phase Shifting of Circadian Rhythms and Depression of Neuronal Activity in the Rat Suprachiasmatic Nucleus by Neuropeptide Y: Mediation by Different Receptor Subtypes [PDF]
Valentin K. Gribkoff+4 more
openalex +1 more source
This study used a tail‐pinching model during development to simulate mechanical pain experienced by pups in high‐social mandarin voles (Microtus mandarinus). Subsequently, brush‐like positive tactile stimuli were applied to the backs of the mandarin voles.
Yahan SUN+14 more
wiley +1 more source
Structural basis for recognition of 26RFa by the pyroglutamylated RFamide peptide receptor
The neuropeptide 26RFa, a member of the RF-amide peptide family, activates the pyroglutamylated RF-amide peptide receptor (QRFPR), a class A GPCR. The 26RFa/QRFPR system plays critical roles in energy homeostasis, making QRFPR an attractive drug target ...
Sanshan Jin+16 more
doaj +1 more source
Obesity and mild hyperinsulinemia found in neuropeptide Y-Y1 receptor-deficient mice [PDF]
Atsuko Kushi+5 more
openalex +1 more source
The Dynamics of the Neuropeptide Y Receptor Type 1 Investigated by Solid-State NMR and Molecular Dynamics Simulation. [PDF]
Vogel A+9 more
europepmc +1 more source
Epidermal Collagen Reduction Drives Selective Aspects of Aging in Sensory Neurons
Reduced collagen on the epidermal apical surface drives selective aging in sensory neurons of Caenorhabditis elegans, leading to excessive dendritic branching and related functional deficits. An immunoglobulin superfamily protein in interneurons acts upstream of collagen genes to maintain dendritic homeostasis during aging, with a downstream ...
Meera M. Krishna+4 more
wiley +1 more source
Central administration of Y5 receptor antisense decreases spontaneous food intake and attenuates feeding in response to exogenous neuropeptide Y [PDF]
Mads Tang‐Christensen+4 more
openalex +1 more source
We found that reducing insulin signalling in adult worms slows down their reproductive ageing and extends their lifespan without negative side effects. Moreover, combining it with IF further enhances these benefits. These interventions likely work by regulating genes linked to biosynthesis and immunity, showing how optimising gene expression can delay ...
Zahida Sultanova+7 more
wiley +1 more source
Expression of Neuropeptide Y Receptors mRNA and Protein in Human Brain Vessels and Cerebromicrovascular Cells in Culture [PDF]
Roger Abounader+6 more
openalex +1 more source