Results 161 to 170 of about 212,465 (393)

Association between neuropeptide Y receptor Y2 promoter variant rs6857715 and major depressive disorder

open access: yesPsychiatric Genetics, 2017
J. Treutlein   +14 more
semanticscholar   +1 more source

Early positive tactile stimulation reverses the increase of anxiety and decrease of sociality induced by early chronic mechanical pain in mandarin voles

open access: yesIntegrative Zoology, EarlyView.
This study used a tail‐pinching model during development to simulate mechanical pain experienced by pups in high‐social mandarin voles (Microtus mandarinus). Subsequently, brush‐like positive tactile stimuli were applied to the backs of the mandarin voles.
Yahan SUN   +14 more
wiley   +1 more source

Structural basis for recognition of 26RFa by the pyroglutamylated RFamide peptide receptor

open access: yesCell Discovery
The neuropeptide 26RFa, a member of the RF-amide peptide family, activates the pyroglutamylated RF-amide peptide receptor (QRFPR), a class A GPCR. The 26RFa/QRFPR system plays critical roles in energy homeostasis, making QRFPR an attractive drug target ...
Sanshan Jin   +16 more
doaj   +1 more source

Obesity and mild hyperinsulinemia found in neuropeptide Y-Y1 receptor-deficient mice [PDF]

open access: green, 1998
Atsuko Kushi   +5 more
openalex   +1 more source

The Dynamics of the Neuropeptide Y Receptor Type 1 Investigated by Solid-State NMR and Molecular Dynamics Simulation. [PDF]

open access: yesMolecules, 2020
Vogel A   +9 more
europepmc   +1 more source

Epidermal Collagen Reduction Drives Selective Aspects of Aging in Sensory Neurons

open access: yesAging Cell, Volume 24, Issue 4, April 2025.
Reduced collagen on the epidermal apical surface drives selective aging in sensory neurons of Caenorhabditis elegans, leading to excessive dendritic branching and related functional deficits. An immunoglobulin superfamily protein in interneurons acts upstream of collagen genes to maintain dendritic homeostasis during aging, with a downstream ...
Meera M. Krishna   +4 more
wiley   +1 more source

Optimising Age‐Specific Insulin Signalling to Slow Down Reproductive Ageing Increases Fitness in Different Nutritional Environments

open access: yesAging Cell, Volume 24, Issue 5, May 2025.
We found that reducing insulin signalling in adult worms slows down their reproductive ageing and extends their lifespan without negative side effects. Moreover, combining it with IF further enhances these benefits. These interventions likely work by regulating genes linked to biosynthesis and immunity, showing how optimising gene expression can delay ...
Zahida Sultanova   +7 more
wiley   +1 more source

Expression of Neuropeptide Y Receptors mRNA and Protein in Human Brain Vessels and Cerebromicrovascular Cells in Culture [PDF]

open access: bronze, 1999
Roger Abounader   +6 more
openalex   +1 more source

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