Aging Cell, EarlyView.The role of mitochondrial translocator protein (TSPO) in hippocampal inflammation is age‐dependent, with TSPO deletion drastically exacerbating inflammation in aged mice, while dampening it in young mice. This TSPO–aging interaction was linked to NF‐kβ and interferon regulatory transcriptional networks. TSPO deletion exacerbated age‐dependent depletion
Kei Onn Lai +7 more
wiley +1 more source
Morphological Evidence for Direct Interaction between Arcuate Nucleus Neuropeptide Y (NPY) Neurons and Gonadotropin-Releasing Hormone Neurons and the Possible Involvement of NPY Y1 Receptors [PDF]
, 1999 C. Li
openalex +1 more source
Aging Cell, EarlyView.In ADR‐induced longevity in C. elegans, neuronal BLI‐4 processes neuropeptides, which are then released with the assistance of UNC‐31 and GOLG‐2. ABSTRACT Dietary restriction (DR) is a well‐established method for extending lifespan across various species, including C. elegans.
Ping Wu +3 more
wiley +1 more source
Cloning and functional expression of a human neuropeptide Y/peptide YY receptor of the Y1 type.
, 1992 Dan Larhammar +5 more
openalex +1 more source
Role of G-protein βγ subunits in the augmentation of P2Y2 (P2U) receptor-stimulated responses by neuropeptide Y Y1 Gi/o-coupled receptors [PDF]
, 1997 A. Lisa SELBIE +3 more
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Aging Cell, EarlyView.Overexpression of GSK‐3β in DG GABAergic neurons impairs neurogenesis by reducing GABA release, which can be reversed by enhancing GABAergic transmission. ABSTRACT The activation of glycogen synthase kinase 3β (GSK‐3β) and the deterioration of spatial memory represent prominent pathological and clinical manifestations of Alzheimer's disease (AD ...
Fei Liu +11 more
wiley +1 more source
Neuropeptide Y Y2 receptors in hypothalamic neuroendocrine areas are up-regulated by estradiol and decreased by progesterone cotreatment in the ovariectomized rat. [PDF]
, 1996 Steven L. Parker +5 more
openalex +1 more source
Mechanisms of alcohol influence on fear conditioning: A computational model
Alcohol, Clinical and Experimental Research, EarlyView.Computational models can test mechanistic relationships between fear conditioning, neuroadaptations, and alcohol. Simulated fear extinction is slower and less robust under alcohol, as greater basolateral amygdala activation is needed. Alcohol shifts the amygdala network away from robust extinction by inhibiting central amygdala activity.
Adam Lonnberg +2 more
wiley +1 more source
In vivo receptor characterization of neuropeptide Y‐induced effects in consecutive vascular sections of cat skeletal muscle [PDF]
, 1997 Ulf Ekelund, David Erlinge
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Alcohol, Clinical and Experimental Research, EarlyView.Prenatal alcohol exposure (PAE) and early‐life adversity (ELA) independently and interactively disrupted neural activity within the social behavior network in adolescent rats, with age‐ and sex‐specific effects. PAE primarily dampened amygdala activity, while ELA altered medial prefrontal cortex responses. These findings reveal how different early‐life
Parker J. Holman +5 more
wiley +1 more source