Results 11 to 20 of about 212,465 (393)

Cloning and Functional Expression of a cDNA Encoding a Human Type 2 Neuropeptide Y Receptor [PDF]

Journal of Biological Chemistry, 1995
Neuropeptide Y (NPY) is a 36-amino acid polypeptide that is widely distributed in the central nervous system and periphery. Pharmacological studies have suggested that there are at least three receptor subtypes, Y1, Y2, and Y3.
Patricia M. Rose, Prabhavathi Fernandes, Jean S. Lynch, Scott T. Frazier, Susan Fisher, Krishna Kodukula, Bernadette Kienzle, Ramakrishna Seethala   +7 more
openalex   +2 more sources

Role of the Y5 neuropeptide Y receptor in limbic seizures

Proceedings of the National Academy of Sciences of the United States of America, 1999
Neuropeptide Y (NPY) is an inhibitory neuromodulator expressed abundantly in the central nervous system that is suspected of being an endogenous antiepileptic agent that can control propagation of limbic seizures. Electrophysiological and pharmacological
Donald J. Marsh, Scott C. Baraban, Gunther Hollopeter, Richard D. Palmiter   +3 more
openalex   +2 more sources

Neuropeptide F regulates courtship in Drosophila through a male-specific neuronal circuit. [PDF]

eLife, 2019
Male courtship is provoked by perception of a potential mate. In addition, the likelihood and intensity of courtship are influenced by recent mating experience, which affects sexual drive.
Aguilar, Morris A, Ganguly, Anindya, Gurav, Adishthi S, Huang, Jia, Liu, Weiwei, Montell, Craig, Ni, Jinfei D, Wang, Yijin   +7 more
core   +3 more sources

Central Administration of BIBP3226, Neuropeptide Y (NPY) Y1 Receptor Antagonist, does not Inhibit Fasting- and NPY-Induced Food Intake in Neonatal Chicks

The Journal of Poultry Science, 2001
Neuropeptide Y (NPY) is known to be an essential orexigenic signal in mammalian and avian brain. Since NPY receptors in the avian brain have not been clarified, to determine whether Y1 receptor or Y1-like receptor(s) mediates the orexigenic effect of NPY
Shin-ichi Kawakami, Ryuichi Ando, Takashi Bungo, Atsushi Ohgushi, Tetsuya Tachibana, D. Michael Denbow, Mitsuhiro Furuse   +6 more
doaj   +3 more sources

High-affinity neuropeptide Y receptor antagonists. [PDF]

Proceedings of the National Academy of Sciences, 1995
Neuropeptide Y (NPY) is one of the most abundant peptide transmitters in the mammalian brain. In the periphery it is costored and coreleased with norepinephrine from sympathetic nerve terminals. However, the physiological functions of this peptide remain unclear because of the absence of specific high-affinity receptor antagonists.
Johann Leban, R J Slepetis, Marilyn Jansen, Dennis Heyer, Andrew Spaltenstein, O H Viveros, A Tadepalli, Antonio Landavazo, Alejandro J. Daniels, W Harrington, J E Matthews   +10 more
openaire   +4 more sources

Characterisation of Neuropeptide Y Receptor Subtypes by Synthetic NPY Analogues and by Anti-receptor Antibodies [PDF]

Molecules, 2001
Neuropeptide Y (NPY), a 36-mer neuromodulator, binds to the receptors Y1, Y2, Y4 and Y5 with nanomolar affinity. They all belong to the rhodopsin-like G-protein coupled, seven transmembrane helix spanning receptors.
Annette G. Beck-Sickinger, Heike A. Wieland, Chiara Cabrele, Christophe P. Eckard   +3 more
doaj   +2 more sources

Neuropeptide Y receptors: how to get subtype selectivity [PDF]

Frontiers in Endocrinology, 2013
The neuropeptide Y (NPY) system is a multireceptor/multiligand system consisting of four receptors in humans (hY(1), hY(2), hY(4), hY(5)) and three agonists (NPY, PYY, PP) that activate these receptors with different potency. The relevance of this system in diseases like obesity or cancer, and the different role that each receptor plays influencing ...
Jan Stichel, Annette G. Beck-Sickinger, Xavier Pedragosa-Badia   +2 more
openaire   +5 more sources

Evolution of neuropeptide Y/RFamide-like receptors in nematodes

Heliyon
The Neuropeptide Y/RFamide-like receptors belong to the Rhodopsin-like G protein-coupled receptors G protein-coupled receptors (GPCRs) and are involved in functions such as locomotion, feeding and reproduction. With 41 described receptors they form the best-studied group of neuropeptide GPCRs in Caenorhabditis elegans.
Franziska Reinhardt, Anette Kaiser, Simone Prömel, Peter F. Stadler   +3 more
openaire   +5 more sources

Functional correlates of positional and gender-specific renal asymmetry in drosophila [PDF]

, 2012
Accordingly, the physical asymmetry of the tubules in the body cavity is directly adaptive. Now that the detailed machinery underlying internal asymmetry is starting to be delineated, our work invites the investigation, not just of tissues in isolation ...
Al Bratty, M., Chintapalli, V., Davies, S.A., Dow, J.A.T., Herzyk, P., Terhzaz, S., Wang, J., Watson, D.G.   +7 more
core   +22 more sources

Neuropeptide Y/Y5 Receptor Pathway Stimulates Neuroblastoma Cell Motility Through RhoA Activation

Frontiers in Cell and Developmental Biology, 2021
Neuropeptide Y (NPY) has been implicated in the regulation of cellular motility under various physiological and pathological conditions, including cancer dissemination. Yet, the exact signaling pathways leading to these effects remain unknown.
Nouran Abualsaud, Nouran Abualsaud, Nouran Abualsaud, Lindsay Caprio, Susana Galli, Ewa Krawczyk, Lamia Alamri, Shiya Zhu, G. Ian Gallicano, Joanna Kitlinska   +9 more
doaj   +1 more source