Results 21 to 30 of about 47,789 (213)

Echinoderms provide missing link in the evolution of PrRP/sNPF-type neuropeptide signalling

eLife, 2020
Neuropeptide signalling systems comprising peptide ligands and cognate receptors are evolutionarily ancient regulators of physiology and behaviour.
Luis Alfonso Yañez-Guerra, Xingxing Zhong, Ismail Moghul, Thomas Butts, Cleidiane G Zampronio, Alexandra M Jones, Olivier Mirabeau, Maurice R Elphick   +7 more
doaj   +1 more source

Regulation of Feeding and Metabolism by Neuropeptide F and Short Neuropeptide F in Invertebrates

Frontiers in Endocrinology, 2019
Numerous neuropeptide systems have been implicated to coordinately control energy homeostasis, both centrally and peripherally. However, the vertebrate neuropeptide Y (NPY) system has emerged as the best described one regarding this biological process ...
Melissa Fadda, Ilayda Hasakiogullari, Liesbet Temmerman, Isabel Beets, Sven Zels, Liliane Schoofs   +5 more
doaj   +1 more source

Hypoxia-activated neuropeptide Y/Y5 receptor/RhoA pathway triggers chromosomal instability and bone metastasis in Ewing sarcoma

Nature Communications, 2022
Ewing sarcoma tumour cells frequently metastasize to the bone but the molecular mechanisms governing this process are not well understood. Here, the authors show that neuropeptide Y/Y5 receptor pathway is activated in the hypoxic tumour microenvironment,
Congyi Lu, Akanksha Mahajan, Sung-Hyeok Hong, Susana Galli, Shiya Zhu, Jason U. Tilan, Nouran Abualsaud, Mina Adnani, Stacey Chung, Nada Elmansy, Jasmine Rodgers, Olga Rodriguez, Christopher Albanese, Hongkun Wang, Maureen Regan, Valerie Zgonc, Jan Blancato, Ewa Krawczyk, G. Ian Gallicano, Michael Girgis, Amrita Cheema, Ewa Iżycka-Świeszewska, Luciane R. Cavalli, Svetlana D. Pack, Joanna Kitlinska   +24 more
doaj   +1 more source

NPF activates a specific NPF receptor and regulates food intake in Pacific abalone Haliotis discus hannai

Scientific Reports, 2021
Neuropeptides function through G protein-coupled receptors (GPCRs) with high specificity, implying a significant degree of neuropeptide-GPCR coevolution. However, potential neuropeptide signaling systems in non-chordates are relatively elusive.
Kyeong Seop Kim, Mi Ae Kim, Keunwan Park, Young Chang Sohn   +3 more
doaj   +1 more source

Transcriptomic analysis of crustacean neuropeptide signaling during the moult cycle in the green shore crab, Carcinus maenas

BMC Genomics, 2018
Background Ecdysis is an innate behaviour programme by which all arthropods moult their exoskeletons. The complex suite of interacting neuropeptides that orchestrate ecdysis is well studied in insects, but details of the crustacean ecdysis cassette are ...
Andrew Oliphant, Jodi L. Alexander, Martin T. Swain, Simon G. Webster, David C. Wilcockson   +4 more
doaj   +1 more source

NPY1R (neuropeptide Y receptor Y1) [PDF]

Atlas of Genetics and Cytogenetics in Oncology and Haematology, 2011
Review on NPY1R (neuropeptide Y receptor Y1), with data on DNA, on the protein encoded, and where the gene is implicated.
M. Ruscica, E. Dozio, L. Passafaro, P. Magni   +3 more
openaire   +3 more sources

Comparative analysis of blood and breath test for alcohol in forensics

One Health & Risk Management, 2023
Introduction. Alcohol consumption is globally recognized as the third-largest risk factor for premature death, posing significant harm to health. In numerous countries, alcohol stands as the primary cause of nearly a third of total traffic accidents and
Daud SHAKEELA, Gul AJAB, Panezei HAMEEDA   +2 more
doaj  

Seizure-induced overexpression of NPY induces epileptic tolerance in a mouse model of spontaneous recurrent seizures

Frontiers in Molecular Neuroscience, 2022
Epileptic seizures result in pronounced over-expression of neuropeptide Y (NPY). In vivo and in vitro studies revealed that NPY exerts potent anticonvulsive actions through presynaptic Y2 receptors by suppressing glutamate release from principal neurons.
Meinrad Drexel, Günther Sperk
doaj   +1 more source

Neuropeptide Y in the medial habenula alleviates migraine-like behaviors through the Y1 receptor

The Journal of Headache and Pain, 2023
Background Migraine is a highly disabling health burden with multiple symptoms; however, it remains undertreated because of an inadequate understanding of its neural mechanisms.
Chunxiao Yang, Zihua Gong, Xiaochen Zhang, Shuai Miao, Bozhi Li, Wei Xie, Tao Wang, Xun Han, Liang Wang, Zhao Dong, Shengyuan Yu   +10 more
doaj   +1 more source

Evolution of neuropeptide Y/RFamide-like receptors in nematodes

Heliyon
The Neuropeptide Y/RFamide-like receptors belong to the Rhodopsin-like G protein-coupled receptors G protein-coupled receptors (GPCRs) and are involved in functions such as locomotion, feeding and reproduction.
Franziska Reinhardt, Anette Kaiser, Simone Prömel, Peter F. Stadler   +3 more
doaj   +1 more source