The neuropeptide transcriptome of a model echinoderm, the sea urchin Strongylocentrotus purpuratus [PDF]
, 2012 The work reported here was supported by a grant from the University of London Central Research ...
Elphick, MR, Rowe, ML
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Nature Communications, 2022 Ewing sarcoma tumour cells frequently metastasize to the bone but the molecular mechanisms governing this process are not well understood. Here, the authors show that neuropeptide Y/Y5 receptor pathway is activated in the hypoxic tumour microenvironment,
Congyi Lu +24 more
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Towards Probing Conformational States of Y2 Receptor Using Hyperpolarized 129Xe NMR
Molecules, 2023 G protein-coupled receptors can adopt many different conformational states, each of them exhibiting different restraints towards downstream signaling pathways.
Peter Schmidt +8 more
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Antisense mRNA for NPY-Y1 receptor in the medial preoptic area increases prolactin secretion
Brazilian Journal of Medical and Biological Research, 1999 We investigated the participation of neuropeptide Y-Y1 receptors within the medial preoptic area in luteinizing hormone, follicle-stimulating hormone and prolactin release.
N.A. Silveira, C.R. Franci
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Echinoderms provide missing link in the evolution of PrRP/sNPF-type neuropeptide signalling
eLife, 2020 Neuropeptide signalling systems comprising peptide ligands and cognate receptors are evolutionarily ancient regulators of physiology and behaviour.
Luis Alfonso Yañez-Guerra +7 more
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What doesn't kill you makes you stranger: Dipeptidyl peptidase-4 (CD26) proteolysis differentially modulates the activity of many peptide hormones and cytokines generating novel cryptic bioactive ligands [PDF]
, 2019 Dipeptidyl peptidase 4 (DPP4) is an exopeptidase found either on cell surfaces where it is highly regulated in terms of its expression and surface availability (CD26) or in a free/circulating soluble constitutively available and intrinsically active form.
Aguilar-Pérez, Alexandra +13 more
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Cloned human neuropeptide Y receptor couples to two different second messenger systems.
Proceedings of the National Academy of Sciences of the United States of America, 1992 Neuropeptide Y (NPY) is one of the most abundant neuropeptides in the mammalian nervous system and exhibits a diverse range of important physiological activities, including effects on psychomotor activity, food intake, regulation of central endocrine ...
H. Herzog +5 more
semanticscholar +1 more source
Regulation of Feeding and Metabolism by Neuropeptide F and Short Neuropeptide F in Invertebrates
Frontiers in Endocrinology, 2019 Numerous neuropeptide systems have been implicated to coordinately control energy homeostasis, both centrally and peripherally. However, the vertebrate neuropeptide Y (NPY) system has emerged as the best described one regarding this biological process ...
Melissa Fadda +5 more
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Scientific Reports, 2021 Neuropeptides function through G protein-coupled receptors (GPCRs) with high specificity, implying a significant degree of neuropeptide-GPCR coevolution. However, potential neuropeptide signaling systems in non-chordates are relatively elusive.
Kyeong Seop Kim +3 more
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Identification and Characterization of the Corazonin Receptor and Possible Physiological Roles of the Corazonin-Signaling Pathway in Rhodnius prolixus. [PDF]
, 2016 Neuropeptides control many physiological and endocrinological processes in animals, acting as neuroactive chemicals within the central and peripheral nervous systems.
Hamoudi, Zina +2 more
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