Results 21 to 30 of about 212,465 (393)

Correlations of Gene Variants LEP rs2167270, LEPR rs1137100, GHRL rs696217, rs27647, and NPY rs16147 with Obesity and Adolescent Eating Behavior: Case-Control Study

Вопросы современной педиатрии, 2022
Background. Childhood obesity is topical global healthcare issue. The correlations between variable regions of genes encoding leptin and its receptor, ghrelin and neuropeptide Y, and the risk of obesity development in children have not been confirmed ...
Olga V. Kochetova, Ziliya A. Shangareeva, Tatyana V. Viktorova, Gulnaz F. Korytina, Vitaliy V. Viktorov   +4 more
doaj   +1 more source

Rabbit Annulus Fibrosus Cells Express Neuropeptide Y, Which Is Influenced by Mechanical and Inflammatory Stress [PDF]

Neurospine, 2020
Objective Rabbit annulus fibrosus (AF) cells were exposed to isolated or combined mechanical and inflammatory stress to examine the expression of neuropeptide Y (NPY).
Malcolm E. Dombrowski, Adam S. Olsen, Nicholas Vaudreuil, Brandon K. Couch, Qing Dong, Michelle Tucci, Joon Y. Lee, Nam V. Vo, Gwendolyn Sowa   +8 more
doaj   +1 more source

The effect of human wharton’s jelly-derived mesenchymal stem cells on MC4R, NPY, and LEPR gene expression levels in rats with streptozotocin-induced diabetes [PDF]

Iranian Journal of Basic Medical Sciences, 2020
Objective(s): Type 1 diabetes (T1D) is an autoimmune disease resulting from inflammatory destruction of islets β-cells. Nowadays, progress in cell therapy, especially mesenchymal stem cells (MSCs) proposes numerous potential remedies for T1D. We aimed to
Fatemeh Sabet Sarvestani, Mohammad Ali Zare, Forough saki, Farhad Koohpeyma, Ismail H. al-Abdullah, Negar Azarpira   +5 more
doaj   +1 more source

Identification of neuropeptides and neuropeptide receptor genes in Phauda flammans (Walker)

Scientific Reports, 2022
Neuropeptides and neuropeptide receptors are crucial regulators to insect physiological processes. The 21.0 Gb bases were obtained from Illumina sequencing of two libraries representing the female and male heads of Phauda flammans (Walker) (Lepidoptera ...
Hai-Pan Wu, Xiao-Yun Wang, Jin Hu, Ran-Ran Su, Wen Lu, Xia-Lin Zheng   +5 more
doaj   +1 more source

Lateral hypothalamic leptin receptor neurons drive hunger-gated food-seeking and consummatory behaviours in male mice

Nature Communications, 2023
Eating behviours consist of seeking and consummatory phases. Here, authors show that two distinct lateral hypothalamic leptin receptor neurons orchestrate seeking and consummatory phases of eating behaviour via hunger signal, Neuropeptide Y.
Young Hee Lee, Yu-Been Kim, Kyu Sik Kim, Mirae Jang, Ha Young Song, Sang-Ho Jung, Dong-Soo Ha, Joon Seok Park, Jaegeon Lee, Kyung Min Kim, Deok-Hyeon Cheon, Inhyeok Baek, Min-Gi Shin, Eun Jeong Lee, Sang Jeong Kim, Hyung Jin Choi   +15 more
doaj   +1 more source

Neuropeptide Y receptors in GtoPdb v.2023.1 [PDF]

, 2023
Neuropeptide Y (NPY) receptors (nomenclature as agreed by the NC-IUPHAR Subcommittee on Neuropeptide Y Receptors [158]) are activated by the endogenous peptides neuropeptide Y, neuropeptide Y-(3-36), peptide YY, PYY-(3-36) and pancreatic polypeptide (PP).
Beck-Sickinger, Annette G., Colmers, William F., Cox, Helen M., Doods, Henri N., Herzog, Herbert, Larhammar, Dan, Michel, Martin C., Quirion, Remi, Schwartz, Thue, Westfall, Thomas   +9 more
core   +2 more sources

Role of Zip1 in the regulation of NPY expression by MLT to promote fracture healing in rats

European Journal of Histochemistry, 2020
Our previous study documented that melatonin (MLT) induced the osteogenic differentiation of mesenchymal stem cells (MSCs) and promoted the healing of femoral fractures in rats via the neuropeptide Y (NPY)/neuropeptide Y1 receptor (NPY1R) signaling ...
Junjun Shang, Bin Ma, Guiling Zhu, Penghong Dong, Chan Wang, Xiaochuan Gu, Ying Zi   +6 more
doaj   +1 more source

Structural basis for ligand recognition of the neuropeptide Y Y2 receptor

Nature Communications, 2021
The human neuropeptide Y receptor Y2 (Y2R) is a drug target for the treatment of obesity and anxiety. Crystal structure of Y2R bound to a selective antagonist and accompanying mutagenesis provide insights into ligand recognition and subtype specificity ...
Tingting Tang, Christin Hartig, Qiuru Chen, Wenli Zhao, Anette Kaiser, Xuefeng Zhang, Hui Zhang, Honge Qu, Cuiying Yi, Limin Ma, Shuo Han, Qiang Zhao, Annette G. Beck-Sickinger, Beili Wu   +13 more
doaj   +1 more source

Intranasal Delivery of Galanin 2 and Neuropeptide Y1 Agonists Enhanced Spatial Memory Performance and Neuronal Precursor Cells Proliferation in the Dorsal Hippocampus in Rats

Frontiers in Pharmacology, 2022
A need for new therapeutic approaches are necessary for dementia conditions and memory deficits of different origins, such as Alzheimer's disease. There is complex pathophysiological mechanisms involved, affecting adult hippocampal neurogenesis, in which
Dasiel O. Borroto-Escuela, Dasiel O. Borroto-Escuela, Dasiel O. Borroto-Escuela, Ramón Fores, Ramón Fores, Mariana Pita, Mariana Pita, Mariana Pita, Miguel A. Barbancho, Pablo Zamorano‐Gonzalez, Natalia García Casares, Kjell Fuxe, Manuel Narváez, Manuel Narváez   +13 more
doaj   +1 more source

Platelet lysate-derived neuropeptide y influences migration and angiogenesis of human adipose tissue-derived stromal cells [PDF]

, 2018
Neuropeptide Y (NPY), a powerful neurotransmitter of the central nervous system, is a key regulator of angiogenesis and biology of adipose depots. Intriguingly, its peripheral vascular and angiogenic powerful activity is strictly associated to platelets,
Bordin, Antonella, Businaro, Rita, Capoano, Raffaele, Corsi, Mariangela, DE FALCO, Elena, Frati, Giacomo, Pagano, Francesca, Petrozza, Vincenzo, Pierangelatotta,, Procaccini, Eugenio, Salvati, Bruno, Scaccia, Eleonora, Siciliano, Camilla, Teresa Vietri, Maria   +13 more
core   +2 more sources