Results 31 to 40 of about 212,465 (393)

DINeR: Database for Insect Neuropeptide Research [PDF]

, 2017
Neuropeptides are responsible for regulating a variety of functions, including development, metabolism, water and ion homeostasis, and as neuromodulators in circuits of the central nervous system.
Davies, Shireen-Anne, Dow, Julian, Nässel, Dick R., Pandit, Aniruddha A., Yeoh, Joseph G.C., Zandawala, Meet   +5 more
core   +1 more source

Coordinated RNA-Seq and peptidomics identify neuropeptides and G-protein coupled receptors (GPCRs) in the large pine weevil Hylobius abietis, a major forestry pest [PDF]

, 2018
Hylobius abietis (Linnaeus), or large pine weevil (Coleoptera, Curculionidae), is a pest of European coniferous forests. In order to gain understanding of the functional physiology of this species, we have assembled a de novo transcriptome of H. abietis,
Davies, Shireen-Anne, Dow, Julian A.T., Inward, Daegan J.G., Marley, Richard, Pandit, Aniruddha A., Predel, Reinhard, Ragionieri, Lapo, Yeoh, Joseph G.C.   +7 more
core   +1 more source

Structural basis of neuropeptide Y signaling through Y1 receptor

Nature Communications, 2022
The human neuropeptide Y (NPY) acts through G-protein coupled receptors and is involved in food intake, stress response, anxiety, and memory retention.
Chaehee Park, Jinuk Kim, Seung-Bum Ko, Yeol Kyo Choi, Hyeongseop Jeong, Hyeonuk Woo, Hyunook Kang, Injin Bang, Sang Ah Kim, Tae-Young Yoon, Chaok Seok, Wonpil Im, Hee-Jung Choi   +12 more
doaj   +1 more source

A companion to the preclinical common data elements and case report forms for neuropathology studies in epilepsy research. A report of the TASK3 WG2 Neuropathology Working Group of the ILAE/AES Joint Translational Task Force

Epilepsia Open, EarlyView., 2022
Abstract The International League Against Epilepsy/American Epilepsy Society (ILAE/AES) Joint Translational Task Force initiated the TASK3 working group to create common data elements (CDEs) for various aspects of preclinical epilepsy research studies, which could help improve the standardization of experimental designs.
Eleonora Aronica, Devin K. Binder, Meinrad Drexel, Chrysanthy Ikonomidou, Shilpa D. Kadam, Guenther Sperk, Christian Steinhäuser   +6 more
wiley   +1 more source

Hypoxia-activated neuropeptide Y/Y5 receptor/RhoA pathway triggers chromosomal instability and bone metastasis in Ewing sarcoma

Nature Communications, 2022
Ewing sarcoma tumour cells frequently metastasize to the bone but the molecular mechanisms governing this process are not well understood. Here, the authors show that neuropeptide Y/Y5 receptor pathway is activated in the hypoxic tumour microenvironment,
Congyi Lu, Akanksha Mahajan, Sung-Hyeok Hong, Susana Galli, Shiya Zhu, Jason U. Tilan, Nouran Abualsaud, Mina Adnani, Stacey Chung, Nada Elmansy, Jasmine Rodgers, Olga Rodriguez, Christopher Albanese, Hongkun Wang, Maureen Regan, Valerie Zgonc, Jan Blancato, Ewa Krawczyk, G. Ian Gallicano, Michael Girgis, Amrita Cheema, Ewa Iżycka-Świeszewska, Luciane R. Cavalli, Svetlana D. Pack, Joanna Kitlinska   +24 more
doaj   +1 more source

Towards Probing Conformational States of Y2 Receptor Using Hyperpolarized ¹²⁹Xe NMR

Molecules, 2023
G protein-coupled receptors can adopt many different conformational states, each of them exhibiting different restraints towards downstream signaling pathways.
Peter Schmidt, Alexander Vogel, Benedikt Schwarze, Florian Seufert, Kai Licha, Virginia Wycisk, Wolfgang Kilian, Peter W. Hildebrand, Lorenz Mitschang   +8 more
doaj   +1 more source

Antisense mRNA for NPY-Y1 receptor in the medial preoptic area increases prolactin secretion

Brazilian Journal of Medical and Biological Research, 1999
We investigated the participation of neuropeptide Y-Y1 receptors within the medial preoptic area in luteinizing hormone, follicle-stimulating hormone and prolactin release.
N.A. Silveira, C.R. Franci
doaj   +1 more source

Echinoderms provide missing link in the evolution of PrRP/sNPF-type neuropeptide signalling

eLife, 2020
Neuropeptide signalling systems comprising peptide ligands and cognate receptors are evolutionarily ancient regulators of physiology and behaviour.
Luis Alfonso Yañez-Guerra, Xingxing Zhong, Ismail Moghul, Thomas Butts, Cleidiane G Zampronio, Alexandra M Jones, Olivier Mirabeau, Maurice R Elphick   +7 more
doaj   +1 more source

The neuropeptide transcriptome of a model echinoderm, the sea urchin Strongylocentrotus purpuratus [PDF]

, 2012
The work reported here was supported by a grant from the University of London Central Research ...
Elphick, MR, Rowe, ML
core   +1 more source

Cloned human neuropeptide Y receptor couples to two different second messenger systems.

Proceedings of the National Academy of Sciences of the United States of America, 1992
Neuropeptide Y (NPY) is one of the most abundant neuropeptides in the mammalian nervous system and exhibits a diverse range of important physiological activities, including effects on psychomotor activity, food intake, regulation of central endocrine ...
H. Herzog, Y. Hort, H. Ball, G. Hayes, J. Shine, L. Selbie   +5 more
semanticscholar   +1 more source