Results 51 to 60 of about 47,789 (213)

A Novel Integrative Mechanism in Anxiolytic Behavior Induced by Galanin 2/Neuropeptide Y Y1 Receptor Interactions on Medial Paracapsular Intercalated Amygdala in Rats

Frontiers in Cellular Neuroscience, 2018
Anxiety is evoked by a threatening situation and display adaptive or defensive behaviors, found similarly in animals and humans. Neuropeptide Y (NPY) Y1 receptor (NPYY1R) and Galanin (GAL) receptor 2 (GALR2) interact in several regions of the limbic ...
Manuel Narváez, Dasiel O. Borroto-Escuela, Dasiel O. Borroto-Escuela, Dasiel O. Borroto-Escuela, Luis Santín, Carmelo Millón, Belén Gago, Antonio Flores-Burgess, Miguel A. Barbancho, Miguel Pérez de la Mora, José Narváez, Zaida Díaz-Cabiale, Kjell Fuxe   +12 more
doaj   +1 more source

Research on Correlation Between Psychological Factors, Mast Cells, and PAR-2 Signal Pathway in Irritable Bowel syndrome

Journal of Inflammation Research, 2021
Guanqun Chao,1 Zhaojun Wang,2 Shuo Zhang3 1Department of General Practice, Sir Run Run Shaw Hospital, Zhejiang University, Hangzhou, People’s Republic of China; 2The First Clinical Medical College of Zhejiang Chinese Medicine University, Hangzhou ...
Chao G, Wang Z, Zhang S
doaj  

A Promising Therapeutic Target for Metabolic Diseases: Neuropeptide Y Receptors in Humans

Cellular Physiology and Biochemistry, 2017
Human neuropeptide Y (hNPY) is one of the most widely expressed neurotransmitters in the human central and peripheral nervous systems. It consists of 36 highly conserved amino acid residues, and was first isolated from the porcine hypothalamus in 1982 ...
Min Yi, Hekai Li, Zhiye Wu, Jianyun Yan, Qicai Liu, Caiwen Ou, Minsheng Chen   +6 more
doaj   +1 more source

Epigenetic modification of hypothalamic neuropeptides and metabolic hormone receptors in metabolic health

Frontiers in Endocrinology
The hypothalamus plays a central role in regulating metabolism by integrating neuropeptide signaling with environmental cues to maintain energy homeostasis.
Busayo Oladun, Smita Mall, Min-Hyun Kim
doaj   +1 more source

Neuropeptide Y receptor Y2 (npy2r) deficiency reduces anxiety and increases food intake in Japanese medaka (Oryzias latipes). [PDF]

Front Cell Dev Biol, 2023
Lu K, Jia X, Wu J, Wang Q, Liang XF.
europepmc   +1 more source

Characterisation of Neuropeptide Y Receptor Subtypes by Synthetic NPY Analogues and by Anti-receptor Antibodies

Molecules, 2001
Neuropeptide Y (NPY), a 36-mer neuromodulator, binds to the receptors Y1, Y2, Y4 and Y5 with nanomolar affinity. They all belong to the rhodopsin-like G-protein coupled, seven transmembrane helix spanning receptors.
Annette G. Beck-Sickinger, Heike A. Wieland, Chiara Cabrele, Christophe P. Eckard   +3 more
doaj   +1 more source

Neuropeptide Y neurons mediate opioid-induced itch by disinhibiting GRP-GRPR microcircuits in the spinal cord

Nature Communications
Itch is a common side effect of opioid analgesics. The specific neurons mediating opioid-induced itch are still debated, and the mechanistic neuronal circuits remain elusive.
Qian Zeng, Yitong Li, Yifei Wu, Jiawei Wu, Kangtai Xu, Yiming Chen, Yunfei Rao, Nan Li, Yuhui Luo, Changyu Jiang, Chaoran Wu, Zilong Wang   +11 more
doaj   +1 more source

Neuropeptide Y in the amygdala contributes to neuropathic pain-like behaviors in rats via the neuropeptide Y receptor type 2/mitogen-activated protein kinase axis. [PDF]

Bioengineered, 2022
Yan W, Liu W, Wu J, Wu L, Xuan S, Wang W, Shang A.   +6 more
europepmc   +1 more source

Chicken neuropeptide Y-family receptor Y4: a receptor with equal affinity for pancreatic polypeptide, neuropeptide Y and peptide YY [PDF]

, 2002
Ingrid Lundell, Timothy Boswell, Dan Larhammar   +2 more
openalex   +1 more source

Adeno-associated viral vector-induced overexpression of neuropeptide Y Y2 receptors in the hippocampus suppresses seizures [PDF]

, 2010
David P.D. Woldbye, Mikael Ängehagen, Casper R. Gøtzsche, Heidi Elbrønd-Bek, Andreas T. Sørensen, Søren H. Christiansen, Mikkel Vestergaard Olesen, Litsa Nikitidou, Thomas van Overeem Hansen, Irene Kanter‐Schlifke, Mérab Kokaia   +10 more
openalex   +1 more source