Results 171 to 180 of about 206,368 (387)

Cloning and functional expression of a human neuropeptide Y/peptide YY receptor of the Y1 type.

open access: hybrid, 1992
Dan Larhammar   +5 more
openalex   +1 more source

TRPA1 ion channel activation context‐dependently regulates gene expression in normal and psoriatic human skin

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Psoriasis is a chronic, relapsing, immune‐mediated inflammatory skin disease. The transient receptor potential ankyrin 1 (TRPA1) ion channel plays a protective role in the formation of psoriasiform skin reactions. Here, we investigated the pharmacological activation and blockade of TRPA1 in human skin (patho)physiology ...
Ágnes Kemény   +10 more
wiley   +1 more source

Effects of neuropeptide Y on electrical activity and myocardial contractility

open access: yesУчёные записки Казанского университета: Серия Естественные науки, 2018
Neuropeptide Y (NPY) and agonist Leu(31)Pro(34)NPY were used to determine the type of NPY receptors involved in electrical activity and myocardial contraction.
A.A. Zverev   +6 more
doaj  

Beyond synapses: cytoplasmic connections in brain function and evolution

open access: yesBiological Reviews, EarlyView.
ABSTRACT Following Ramón y Cajal's groundbreaking contributions to the identification of synapses, research in neuroscience predominantly focused on their pivotal role in neural communication (the neuron doctrine), overlooking an intriguing possibility suggested by Golgi of non‐synaptic interactions among neural cells.
Malalaniaina Rakotobe, Chiara Zurzolo
wiley   +1 more source

Structural basis for recognition of 26RFa by the pyroglutamylated RFamide peptide receptor

open access: yesCell Discovery
The neuropeptide 26RFa, a member of the RF-amide peptide family, activates the pyroglutamylated RF-amide peptide receptor (QRFPR), a class A GPCR. The 26RFa/QRFPR system plays critical roles in energy homeostasis, making QRFPR an attractive drug target ...
Sanshan Jin   +16 more
doaj   +1 more source

Neurobeachin (NBEA) is a novel gene associated with GLP‐1 receptor agonist associated weight loss

open access: yesDiabetes, Obesity and Metabolism, EarlyView.
Abstract Aims Nearly 42% of adults in the United States have obesity, a significant risk factor for many cardiometabolic diseases and cancers. Glucagon‐like peptide‐1 receptor agonists (GLP‐1RAs) are promising interventions for weight loss, but their efficacy varies significantly across individuals.
Arshiya Mariam‐Smith   +6 more
wiley   +1 more source

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