Results 41 to 50 of about 72,976 (300)

Phylogenetic investigation of peptide hormone and growth factor receptors in five dipteran genomes

Frontiers in Endocrinology, 2013
Peptide hormones and growth factors bind to membrane receptors and regulate a myriad of processes in insects and other metazoans. The evolutionary relationships among characterized and un-characterized (orphan) receptors can provide insights into ...
Kevin J. Vogel, Mark R Brown, Michael R Strand   +2 more
doaj   +1 more source

Functional and genetic characterization of neuropeptide Y-like receptors in Aedes aegypti. [PDF]

PLoS Neglected Tropical Diseases, 2013
BACKGROUND:Female Aedes aegypti mosquitoes are the principal vector for dengue fever, causing 50-100 million infections per year, transmitted between human and mosquito by blood feeding. Ae.
Jeff Liesch, Lindsay L Bellani, Leslie B Vosshall   +2 more
doaj   +1 more source

N-Arachidonoyl Dopamine Modulates Acute Systemic Inflammation via Nonhematopoietic TRPV1. [PDF]

, 2017
N-Arachidonoyl dopamine (NADA) is an endogenous lipid that potently activates the transient receptor potential vanilloid 1 (TRPV1), which mediates pain and thermosensation. NADA is also an agonist of cannabinoid receptors 1 and 2.
Hellman, Judith, Lawton, Samira K, Prakash, Arun, Schumacher, Mark, Tran, Alphonso, Wilhelmsen, Kevin, Wong, Erika, Xu, Fengyun   +7 more
core   +2 more sources

Renal neuroendocrine control of desiccation and cold tolerance by Drosophila suzukii [PDF]

, 2017
Background: Neuropeptides are central to the regulation of physiological, and behavioural processes in insects, directly impacting cold and desiccation survival.
Al-Anzi, Asplen, Atallah, Audsley, Cabrero, Cabrero, Cannell, Choi, Chown, Cini, Coast, Coast, Condon, Dalton, David, Davies, Denlinger, Dow, Dow, Enriquez, Gerken, Gibbs, Goodhue, Hadley, Halberg, Hoffmann, Hoffmann, Huey, Jakobs, Jakobs, Jensen, Kacar, Kahsai, Kang, Kean, Kelty, Li, Matsumura, Matzkin, McWilliam, Nässel, O'Donnell, Plantamp, Poyet, Rajpurohit, Ryan, Schiffer, Schooley, Shearer, Sinclair, Sinclair, Sinclair, Stephens, Sørensen, Taghert, Telonis-Scott, Terblanche, Terhzaz, Terhzaz, Terhzaz, Tochen, Toxopeus, Wallingford, Yeoh   +63 more
core   +2 more sources

Neuropeptide Y receptor in the rat brain [PDF]

European Journal of Biochemistry, 1984
The specific binding of the chloramine-T iodinated neuropeptide Y (125I-NPY) to membranes from rat cerebral cortex was investigated using equilibrium binding and kinetic methods. The equilibrium binding of 125I-NPY at 37 degrees C was characterized by a Kd value of 0.38 nM. The receptor densities in the cerebral cortex, hypothalamus and cerebellum were
A, Undén, K, Tatemoto, V, Mutt, T, Bartfai   +3 more
openaire   +2 more sources

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

The Role of Calcitonin Gene‐Related Peptide in High‐Altitude Headache: A Prospective Field Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective High‐altitude headache (HAH) is a common neurological condition associated with rapid ascent to high altitude. The pathophysiological mechanisms underlying HAH remain incompletely understood. Calcitonin gene‐related peptide (CGRP), a neuropeptide implicated in migraine pathophysiology, may play a key role in the pathophysiology of ...
Roman Schniepp, Ludwig Karrasch, Helena Breitenstein, Andreas Straube, Katharina Kamm   +4 more
wiley   +1 more source

Impact of Orexin-A Treatment on Food Intake, Energy Metabolism and Body Weight in Mice. [PDF]

PLoS ONE, 2017
Orexin-A and -B are hypothalamic neuropeptides of 33 and 28-amino acids, which regulate many homeostatic systems including sleep/wakefulness states, energy balance, energy homeostasis, reward seeking and drug addiction.
Anne Blais, Gaëtan Drouin, Catherine Chaumontet, Thierry Voisin, Anne Couvelard, Patrick Christian Even, Alain Couvineau   +6 more
doaj   +1 more source

Cloning characterisation and expression of a G-protein-couple receptor from Lymnaea stagnalis and identification of a leucokinin-like peptide PSFHSWSamide as its endogenous ligand [PDF]

, 1997
No description ...
Burke, Julian F, Cox, Kingsley J A, Geraerts, Wijnand P M, Li, Ka Wan, Tensen, Cornelis P, Van der Schors, Roel C, van Heerikhuizen, Harm, Vreugdenhil, Erno   +7 more
core   +1 more source

Coacervates Made of Elastin‐Like Polypeptides Fused with Melanocyte‐Stimulating Hormone and Monocyte Chemoattractant Protein Enhance Skin Wound Healing in Spinal Cord‐Injured Mice

Advanced Healthcare Materials, EarlyView.
Pressure skin wounds are frequent complications after spinal cord injury (SCI), with impaired healing due to vascular and immune deficits. Elastin‐like polypeptides (ELP) fused to α‐MSH (MSH‐ELP) or MCP‐1 (MCP‐ELP) are developed and tested on these wounds. The resulting nanoparticles are non‐toxic and bioactive, and they enhance macrophage recruitment,
Suneel Kumar, Dhruv Patel, Greeshma Manjunath, Shashank Madhavan, Ashley Mathew, Dnyaneshwari Rananavare, Jahnavi Shah, Francois Berthiaume   +7 more
wiley   +1 more source