Results 111 to 120 of about 17,164 (224)
The role of neuropilin 2 in physiological and pathological angiogenesis and lymphangiogenesis [PDF]
The generation of new lymphatic vessels through lymphangiogenesis has been implicated in many disease states. This process has some overlap with the better studied angiogenesis pathway, but is under distinct molecular control.
Mucka, Patrick
core
Neuropilin-1 is henceforth a relevant target in cancer treatment; however, its way of action remains partly elusive, and the development of small inhibitory molecules is therefore required for its study.
Lucia Borriello +9 more
doaj +1 more source
Expression of neuropilin-1 by human glomerular epithelial cells in vitro and in vivo
Vascular endothelial growth factor (VEGF) is a potent promoter of endothelial mitogenesis and of endothelial permeability. Within the kidney it is synthesized primarily in the visceral glomerular epithelial cells (vGECs); however, the role of VEGF in the
Peat, D +6 more
core +1 more source
Neuropilin is a neuronal cell surface protein and has been shown to function as a receptor for a secreted protein, semaphorin III/D, that can induce neuronal growth cone collapse and repulsion of neurites in vitro.
Yagi, Takeshi +7 more
core +1 more source
Structural and functional analysis of the heparin-binding domain of VEGF164.
Several of the multitude of functions attributed to Vascular Endothelial Growth Factor-A (VEGF-A) are coordinated by its various isoforms, which are generated as a result of alternative splicing from a single gene. Despite the fact that the VEGF isoforms
Krilleke, D.
core
Comparison of neuropilin-1 (NRP-1) and neuropilin-2 (NRP-2) expression on alveolar macrophages in lung cancer adjacent to the cancer margin, lung inflammation and lung tissue remote to the cancer nest (physiologically normal lung).
Hongxue Meng (2272915) +6 more
core +1 more source
Relevance of Neuropilin 1 and Neuropilin 2 Targeting for Cancer Treatment [PDF]
openaire +1 more source
A complementary peptide approach applied to the design of novel semaphorin/neuropilin antagonists
Semaphorin 3A can inhibit axonal growth and induce neuronal apoptosis following binding to neuropilin-1, with the membrane proximal MAM (meprin, A5, mu) domain in neuropilin-1 playing a key role in the formation of a higher order receptor complex.
Eickholt, B J +11 more
core +1 more source
Coexpression of neuropilin-1, Flk1, and VEGF164in developing and mature mouse kidney glomeruli
Neuropilin-1, a neuronal cell surface semaphorin III receptor protein important for axonal guidance in developing peripheral nervous system efferents, has also been identified as a vascular endothelial growth factor (VEGF) receptor on endothelial cells ...
Barry Robert +2 more
core +1 more source

