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Adipose Tissue in SARS-CoV-2 Viral Tropism, Viral Replication, and the Concept of a Viral Reservoir: An Update. [PDF]

Obesity (Silver Spring)
Maher LC, Ryan PM, Caplice NM.
europepmc   +1 more source

Corrigendum for figure-related and funding acknowledgement corrections in previously published articles of <i>Bioactive Materials</i>. [PDF]

Bioact Mater
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Neuropilin‐2 expression in cancer

Histopathology, 2012
Jubb A M, Sa S M, Ratti N, Strickland L A, Schmidt M, Callahan C A & Koeppen H 
(2012) Histopathology 61, 340–349Neuropilin‐2 expression in cancerAims:  Neuropilin‐2 is a coreceptor for vascular endothelial growth factor family members. Blockade of neuropilin‐2 is able to suppress lymphogenous metastasis in preclinical models. The aim of this study
Adrian M, Jubb, Susan M, Sa, Navneet, Ratti, Laura A, Strickland, Maike, Schmidt, Christopher A, Callahan, Hartmut, Koeppen   +6 more
exaly   +3 more sources

Neuropilins in Tumor Biology

Clinical Cancer Research, 2009
Abstract The neuropilin receptors were first discovered as regulators of nervous system development, acting as semaphorin coreceptors with plexins. Subsequently, the neuropilins were identified as receptors for vascular endothelial growth factor.
Anil, Bagri, Marc, Tessier-Lavigne, Ryan J, Watts   +2 more
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Neuropilin is a Mediator of Angiogenesis

Cancer and Metastasis Reviews, 2000
Neuropilin is both a receptor for semaphorins, which are mediators of neuronal guidance, and for VEGF, an angiogenesis factor. While the function of neuropilin in the nervous system has been characterized, its role in angiogenesis is only beginning to be elucidated.
H Q, Miao, M, Klagsbrun
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Neuropilin regulation of angiogenesis

Biochemical Society Transactions, 2014
Blood vessel formation during vertebrate development relies on a process called angiogenesis and is essential for organ growth and tissue viability. In addition, angiogenesis leads to pathological blood vessel growth in diseases with tissue ischaemia, such as neovascular eye disease and cancer. Neuropilin 1 (NRP1) is a transmembrane protein that serves
Anastasia, Lampropoulou, Christiana, Ruhrberg   +1 more
openaire   +2 more sources

Multifaceted Role of Neuropilins in Cancer

Current Medicinal Chemistry, 2011
Neuropilins comprise two homologous widely-expressed single-pass plasma membrane receptors (Nrp1 and Nrp2), originally identified for binding secreted Semaphorins and Vascular Endothelial Growth Factors (in association with Plexins and VEGF-Receptors).
Rizzolio, S., Tamagnone, L.
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Neuropilin 2 and soluble neuropilin 2 in neuroendocrine neoplasms

Endocrine-Related Cancer
Neuropilin 2 (NRP2), a transmembrane non-tyrosine kinase receptor, has been described as a potential critical player in the tumourigenesis of several solid cancers and particularly in neuroendocrine neoplasms (NENs). A soluble form of NRP2 (sNRP2) has been previously described and corresponds to a truncated splice isoform.
Laura Gerard, Céline Patte, Laurence Chardon, Valérie Hervieu, Léa Payen, Marion Allio, Claire Marx, Hugo Clermidy, Alice Durand, Patrick Mehlen, Julien Bollard, Gilles Poncet, Colette Roche, Benjamin Gibert, Thomas Walter   +14 more
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