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Expression and mapping of duplicate neuropilin-1 and neuropilin-2 genes in developing zebrafish

Gene Expression Patterns, 2004
Previously, we described the isolation and characterization of the first zebrafish neuropilin gene, which we now call nrp1a, and found its protein to be a mediator of vascular endothelial growth factor (VEGF)-dependent angiogenesis [Proc. Natl Acad. Sci. USA 99 (2002) 10470].
Diane E, Bovenkamp   +8 more
openaire   +2 more sources

Neuropilin 1 and Neuropilin 2: Cancer Progression and Biomarker Analysis

2017
Neuropilins (NRP, human; Nrp, mouse) are a family of cell surface protein receptors originally named for their role in neuronal guidance during embryonic development. Over the past two decades, the expression, localization, regulation, and function of the NRP family have been intensely studied.
Xiaoran Li, Diane R. Bielenberg
openaire   +1 more source

The Function of Neuropilin/L1 Complex

2002
L1, a cell adhesion molecule of the Ig superfamily (IgCAM) plays a critical role in the formation of neuronal networks. This is reflected by the variety of clinical signs associated with the X-linked recessive neurological disorder that is caused by mutations in the L1 gene.
openaire   +3 more sources

Flow regulation of Neuropilin-1 and the role of Neuropilin-1 in mechanotransduction

2011
Le concept de l'angiogénèse est simple et bien défini, comme la formation de nouveaux vaisseaux sanguins à partir de vaisseaux préexistants, mais son mécanisme est complexe, et implique une multitude de facteurs qui sont encore méconnus. Une des choses que nous savons avec certitude, est que l'angiogénèse est une composante vitale de la vie, autant que
openaire   +1 more source

Neuropilin invites reoviruses into neurons

Cell Host & Microbe
In this issue of Cell Host & Microbe, Shang et al. identify murine neuropilin 1 as a host factor that binds reovirus particles, directing cell entry and contributing to viral dissemination and neurovirulence. This study highlights the reovirus model system to investigate host receptors and their significance in viral pathogenesis.
openaire   +2 more sources

The Function of Neuropilin/Plexin Complexes

2002
Neuropilins bind the secreted class 3 semaphorins with high affinity but require a member of the plexin family to form receptors that are able to activate downstream signal transduction cascades. In this receptor complex neuropilins act as the ligand-binding subunit while plexins function as the signal-transducing subunit in the induction of ...
openaire   +2 more sources

Role of Neuropilin 1 in COVID-19 Patients with Acute Ischemic Stroke

Biomedicines, 2022
Ali I Al-Gareeb   +2 more
exaly  

Glycosaminoglycan modification of neuropilin-1 modulates VEGFR2 signaling

EMBO Journal, 2006
Yulin Liao   +2 more
exaly  

Determination of Cell Adhesion Sites of Neuropilin-1

Journal of Cell Biology, 2000
Fujisawa Hajime, Murakami Yasunori
exaly  

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