Results 21 to 30 of about 2,570 (152)

Pre, intra and post-ischemic hypothermic neuroprotection in temporary focal cerebral ischemia in rats: morphometric analysis

Arquivos de Neuro-Psiquiatria, 2012
OBJECTIVE: To evaluate the neuroprotection of mild hypothermia, applied in different moments, in temporary focal cerebral ischemia in rats. METHODS: Rats was divided into Control (C), Sham (S), Ischemic-control(IC), Pre-ischemic Hypothermia (IH1), Intra ...
Roberto Alexandre Dezena, Benedicto Oscar Colli, Carlos Gilberto Carlotti Junior, Luís Fernando Tirapelli   +3 more
doaj   +1 more source

Procedimentos para neuroproteção fetal: uso do sulfato de magnésio [PDF]

, 2013
Universidade Federal de São Paulo (UNIFESP) Escola Paulista de Medicina Obstetrics DepartmentUNIFESP, EPM, Obstetrics ...
Araujo Júnior, Edward, Moron, Antonio Fernandes, Nardozza, Luciano Marcondes Machado   +2 more
core   +1 more source

Neuroprotective effect of mild hypothermia in the temporary brain ischemia in cats Efeito neuroprotetor da hipotermia leve na isquemia cerebral focal temporária em gatos

Arquivos de Neuro-Psiquiatria, 2007
OBJECTIVE: To evaluate the neuroprotective effect of mild hypothermia during temporary focal ischemia in cats. METHOD: 20 cats underwent middle cerebral artery 60 minutes occlusion and 24 hours reperfusion: 10 under normothermia and 10 under mild ...
Hiroshi Nakano, Benedicto Oscar Colli, Luiza da Silva Lopes   +2 more
doaj   +1 more source

Selective therapeutic hypothermia: A review of invasive and noninvasive techniques

Arquivos de Neuro-Psiquiatria, 2011
OBJECTIVE: Therapeutic hypothermia is a promising treatment to prevent secondary neurologic injury. Clinical utility is limited by systemic complications of global hypothermia. Selective brain cooling remains a largely uninvestigated application.
David Straus, Vinay Prasad, Lorenzo Munoz   +2 more
doaj   +1 more source

Methylglyoxal Induces Changes in the Glyoxalase System and Impairs Glutamate Uptake Activity in Primary Astrocytes

Oxidative Medicine and Cellular Longevity, Volume 2017, Issue 1, 2017., 2017
The impairment of astrocyte functions is associated with diabetes mellitus and other neurodegenerative diseases. Astrocytes have been proposed to be essential cells for neuroprotection against elevated levels of methylglyoxal (MG), a highly reactive aldehyde derived from the glycolytic pathway.
Fernanda Hansen, Fabiana Galland, Franciane Lirio, Daniela Fraga de Souza, Carollina Da Ré, Rafaela Ferreira Pacheco, Adriana Fernanda Vizuete, André Quincozes-Santos, Marina Concli Leite, Carlos-Alberto Gonçalves, Ana Ledo   +10 more
wiley   +1 more source

Sistemas aquosos bifásicos uma ferramenta sustentável para a extração de ácido clavulânico a partir de diferentes fontes [PDF]

, 2015
O ácido clavulânico (AC) é um inibidor de β-lactamases que tem vindo a ser largamente utilizado na área médica. Embora seja de extrema importância, o desenvolvimento de processos alternativos de produção e purificação é ainda insignificante, sendo ...
Pereira, Jorge F. B., Pessoa Jr, Adalberto, Santos-Ebinuma, Valéria C., Teixeira, J. A.   +3 more
core   +1 more source

Melatoninergic System in Parkinson’s Disease: From Neuroprotection to the Management of Motor and Nonmotor Symptoms

Oxidative Medicine and Cellular Longevity, Volume 2016, Issue 1, 2016., 2016
Melatonin is synthesized by several tissues besides the pineal gland, and beyond its regulatory effects in light‐dark cycle, melatonin is a hormone with neuroprotective, anti‐inflammatory, and antioxidant properties. Melatonin acts as a free‐radical scavenger, reducing reactive species and improving mitochondrial homeostasis.
Josiel Mileno Mack, Marissa Giovanna Schamne, Tuane Bazanella Sampaio, Renata Aparecida Nedel Pértile, Pedro Augusto Carlos Magno Fernandes, Regina P. Markus, Rui Daniel Prediger, Serafina Perrone   +7 more
wiley   +1 more source

Síndrome glaucomatosa em cães: parte 2 Glaucomatous syndrome in dogs: part 2

Ciência Rural, 2007
O glaucoma mantém-se como uma das principais causas de cegueira em pacientes humanos e entre os animais domésticos. No curso da sua patogênese, ocorre aumento da pressão intra-ocular e morte de células retinianas, cujo início pode ser precoce.
Alexandre Pinto Ribeiro, Bianca da Costa Martins, José Luiz Laus   +2 more
doaj   +1 more source

Status epilepticus [PDF]

, 2008
INTRODUÇÃO: O estado de mal epiléptico (EME) é subdiagnosticado, especialmente as formas clínicas com sinais motores sutis ou apenas com alteração da consciência.
GARZON, Eliana
core   +1 more source

Virtual Screening of Acetylcholinesterase Inhibitors Using the Lipinski’s Rule of Five and ZINC Databank

BioMed Research International, Volume 2015, Issue 1, 2015., 2015
Alzheimer’s disease (AD) is a progressive and neurodegenerative pathology that can affect people over 65 years of age. It causes several complications, such as behavioral changes, language deficits, depression, and memory impairments. One of the methods used to treat AD is the increase of acetylcholine (ACh) in the brain by using acetylcholinesterase ...
Pablo Andrei Nogara, Rogério de Aquino Saraiva, Diones Caeran Bueno, Lílian Juliana Lissner, Cristiane Lenz Dalla Corte, Marcos M. Braga, Denis Broock Rosemberg, João Batista Teixeira Rocha, Miroslav Pohanka   +8 more
wiley   +1 more source