Results 61 to 70 of about 118,682 (313)

Effects of Aging on Neural Stem/Progenitor Cells and Oligodendrocyte Precursor Cells after Focal Cerebral Ischemia in Spontaneously Hypertensive Rats

Cell Transplantation, 2016
Aging and vascular comorbidities such as hypertension comprise critical cofactors that influence how the brain responds to stroke. Ischemic stress induces neurogenesis and oligodendrogenesis in younger brains.
Anna C. Liang, Emiri T. Mandeville, Takakuni Maki, Akihiro Shindo, Angel T. Som, Naohiro Egawa, Kanako Itoh, Tsu Tshen Chuang, John D. Mcneish, Julie C. Holder, Josephine Lok, Eng H. Lo, Ken Arai   +12 more
doaj   +1 more source

Engineering Nanoplatforms for Alzheimer's Disease Detection via Biomolecular Corona Proteomic and Lipidomic Profiling

Advanced Healthcare Materials, EarlyView.
Engineered nanoparticles capture disease‐specific biomolecular coronas that uncover hidden molecular features of Alzheimer's disease. Combined proteomic and lipidomic analyses reveal a characteristic shift in ribosomal machinery and energy metabolism, generating a multiomic fingerprint that supports accurate disease detection and opens new ...
Antonietta Greco, Roberto Baretta, Andrea Di Fonzo, Andrea Armirotti, Stefano Cinti, Mara Mirasoli, Marco Frasconi, Claudia Corbo   +7 more
wiley   +1 more source

Promoting Neuro‐Supportive Properties of Astrocytes with Epidermal Growth Factor Hydrogels

Stem Cells Translational Medicine, 2019
Biomaterials provide novel platforms to deliver stem cell and growth factor therapies for central nervous system (CNS) repair. The majority of these approaches have focused on the promotion of neural progenitor cells and neurogenesis.
Su Jing Chan, Wanting Niu, Kazuhide Hayakawa, Gen Hamanaka, Xiaoying Wang, Pike See Cheah, Shuzhen Guo, Zhangyang Yu, Ken Arai, Magdy H. Selim, Motoichi Kurisawa, Myron Spector, Eng H. Lo   +12 more
doaj   +1 more source

Multifunctional Catechol‐Functionalized Cellulose Hydrogels for the Minimally Invasive Treatment of Acute Optic Nerve Injuries

Advanced Healthcare Materials, EarlyView.
Catechol‐functionalized cellulose hydrogels are developed as injectable, bioadhesive platforms for retinal neuroprotection. The hydrogels exhibit tunable rheological and mechanical properties, strong tissue adhesion, and sustained antioxidative activity.
Kai‐Hsiang Chang, Yi‐Ke Lin, Wei‐Li Chen, Ta‐Ching Chen, Jiashing Yu   +4 more
wiley   +1 more source

Mental Privacy and Neuroprotection: An Open Debate [PDF]

, 2022
Current advances in neurotechnology are allowing the gradual decoding of neural information at the basis of a number of conscious mental states with unprecedented level of accuracy.
López-Silva, Pablo, Wajnerman, Paz Abel
core   +1 more source

Sex differences in the role of AKAP12 in behavioral function of middle-aged mice

Biology of Sex Differences
A-kinase anchoring protein 12 (AKAP12) is a key scaffolding protein that regulates cellular signaling by anchoring protein kinase A (PKA) and other signaling molecules.
Hidehiro Ishikawa, Shintaro Kimura, Hajime Takase, Maximillian Borlongan, Norito Fukuda, Tomonori Hoshino, Gen Hamanaka, Ji Hyun Park, Akihiro Shindo, Kyu-Won Kim, Irwin H. Gelman, Josephine Lok, Eng H. Lo, Ken Arai   +13 more
doaj   +1 more source

Research on predictive model for tracheal tube sizes in adult double-lumen endotracheal intubation based on radiomics and artificial intelligence

Frontiers in Medicine
ObjectiveThis study aims to develop a predictive model for tracheal tube sizes in adult double-lumen endotracheal intubation using radiomics and artificial intelligence (AI) technologies to enhance the safety and efficiency of intubation procedures ...
Shaopeng Ming, Zhaoyu Li, Shu Yan, Wei Lan, Hongtao Liu, Yanzhuo Zhang   +5 more
doaj   +1 more source

5-HIAA induces neprilysin to ameliorate pathophysiology and symptoms in a mouse model for Alzheimer’s disease

Acta Neuropathologica Communications, 2018
Serotoninergic activation which decreases brain Aβ peptides is considered beneficial in mouse models for Alzheimer’s disease (AD), but the mechanisms involved remain unclear.
Christian Klein, Guy Roussel, Susana Brun, Cristina Rusu, Christine Patte-Mensah, Michel Maitre, Ayikoe-Guy Mensah-Nyagan   +6 more
doaj   +1 more source

Mechanism‐Driven Nanoformulations for Cognitive Impairment Induced by Intermittent Hypoxia and Periodontitis

Advanced Materials, EarlyView.
Clinically, intermittent hypoxia (IH) is often accompanied by periodontitis, which accelerates cognitive impairment induced by IH. Novel Janus mesoporous gold‐silica nanoformulations (RVG‐Au&mSiO2‐TPP‐VB) enable intranasal delivery, achieve hierarchical targeting to neuronal mitochondria, effectively scavenge reactive oxygen species, inhibit the HIF‐1α/
Kai‐Run Zhang, Tianbao Zhu, An‐Qi Liu, Jia‐Jia Deng, Ya‐Li Han, Sheng‐Cai Qi, Xue Liu, Tian‐Yi Jiang, Ming‐Rui Zhai, Yu‐Ying He, Xiu‐Juan Li, Hong‐Ting Da, Rui Xu, Xiaomin Li, Jun Gao, Yue‐Hua Liu   +15 more
wiley   +1 more source

Neuroprotection with Anaesthetic Agents [PDF]

, 2001
peer reviewedThe term 'neuroprotection' is used to refer to any prophylactic measure that is initiated during the peri-ischaemic period in order to improve neuronal survival.
BONHOMME, Vincent, Hans, Pol
core   +1 more source