Results 51 to 60 of about 128,007 (210)

Promoting Neuro‐Supportive Properties of Astrocytes with Epidermal Growth Factor Hydrogels

Stem Cells Translational Medicine, 2019
Biomaterials provide novel platforms to deliver stem cell and growth factor therapies for central nervous system (CNS) repair. The majority of these approaches have focused on the promotion of neural progenitor cells and neurogenesis.
Su Jing Chan, Wanting Niu, Kazuhide Hayakawa, Gen Hamanaka, Xiaoying Wang, Pike See Cheah, Shuzhen Guo, Zhangyang Yu, Ken Arai, Magdy H. Selim, Motoichi Kurisawa, Myron Spector, Eng H. Lo   +12 more
doaj   +1 more source

The APCs of neuroprotection [PDF]

Journal of Clinical Investigation, 2009
Mutations in the enzyme superoxide dismutase 1 (SOD1) have been linked to the neurodegenerative disease amyotrophic lateral sclerosis (ALS). In this issue of the JCI, Zhong et al. report that the endogenous anticoagulant activated protein C (APC) is able to cross the blood-spinal cord barrier in mice and signal to both neuronal and non-neuronal cells ...
Charles T, Esmon, Jonathan D, Glass
openaire   +2 more sources

The Relevance and Implications of Monoclonal Antibody Therapies on Traumatic Brain Injury Pathologies

Biomedicines
Traumatic brain injury (TBI) is a global public health concern. It remains one of the leading causes of morbidity and mortality. TBI pathology involves complex secondary injury cascades that are associated with cellular and molecular dysfunction ...
Ping Wang, Starlyn Okada-Rising, Anke H. Scultetus, Zachary S. Bailey   +3 more
doaj   +1 more source

Neuroprotection induced by curcumin

Natural Molecules in Neuroprotection and Neurotoxicity brings together research in the area of natural compounds and their dual effects of neuroprotection and neurotoxicity when interacting with brain cells.
Antonietta Messina, Teresa Trotta, Chiara Porro, Maria Antonietta Panaro, Tarek Benameur, Ilaria Pizzolorusso, Giovanni Messina, Melania Ruggiero, Rita Polito   +8 more
core   +1 more source

Molecular targets involved in the neuroprotection mediated by terpenoids

, 2019
Natural products and their derivatives represent the most consistently successful source of drug leads. Terpenoids, a structurally diverse group, are secondary metabolites widely distributed in nature, endowed with a wide range of biological activities ...
Palomino Ruiz-Poveda, Olga María, Heras Polo, Beatriz De Las, Apaza Ticona, Luis Nestor, González Cofrade, Laura   +3 more
core   +1 more source

Assessing the link between cerebellar volume and cognitive function in Alzheimer’s disease: a pilot study

Scientific Reports
The cerebellum, long recognized for its role in motor functions, has become increasingly acknowledged for its involvement in a broader spectrum of cognitive functions.
Deborah Van Rossem, Gert-Jan Allemeersch, Nuno Barros, Joke Temmerman, Marijke Desmet, Ilka Ringoot, Annemie Ribbens, Veronique Michiels, Johan De Mey, Chris Baeken, Sebastiaan Engelborghs, Sara De Witte   +11 more
doaj   +1 more source

Neuroprotection in glaucoma

Indian Journal of Ophthalmology, 2011
Glaucoma is a neurodegenerative disease characterized by loss of retinal ganglion cells and their axons. Recent evidence suggests that intraocular pressure (IOP) is only one of the many risk factors for this disease. Current treatment options for this disease have been limited to the reduction of IOP; however, it is clear now that the disease ...
Vasudevan Sushil, Gupta Viney, Crowston Jonathan   +2 more
openaire   +3 more sources

Insulin Neuroprotection and the Mechanisms

, 2015
Objective: To analyze the mechanism of neuroprotection of insulin and which blood glucose range was benefit for insulin exerting neuroprotective action. Data Sources: The study is based on the data from PubMed.
Li-Yun Yu, Yu Pei
core   +1 more source

Hypothermic neuroprotection [PDF]

Neurotherapeutics, 2006
The possibility that hypothermia during or after resuscitation from asphyxia at birth, or cardiac arrest in adults, might reduce evolving damage has tantalized clinicians for a very long time. It is now known that severe hypoxia-ischemia may not necessarily cause immediate cell death, but can precipitate a complex biochemical cascade leading to the ...
Gunn, AJ, Thoresen, M
openaire   +2 more sources

Diabetes exacerbates brain pathology following a focal blast brain injury: New role of a multimodal drug cerebrolysin and nanomedicine

, 2020
Blast brain injury (bBI) is a combination of several forces of pressure, rotation, penetration of sharp objects and chemical exposure causing laceration, perforation and tissue losses in the brain.
Patnaik, Ranjana,, Nozari, Ala,, Rudy J. Castellani, Sjoquist, Per-Ove,, Aruna Sharma, Castellani, Rudy J.,, Lars Wiklund, Lianyuan Feng, Muresanu, Dafin F.,, Per-Ove Sjöquist, Seaab Sahib, Sharma, Aruna,, Ala Nozari, Ranjana Patnaik, Dafin F. Muresanu, Tian, Z. Ryan,, Hari Shanker Sharma, Feng, Lianyuan,, Vicente Lafuente, Jose,, Z. Ryan Tian, Buzoianu, Anca D.,, Wiklund, Lars,, Sharma, Hari Shanker,, Anca D. Buzoianu, Sahib, Seaab,, José Vicente Lafuente   +25 more
core   +1 more source