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Natural compounds, such as plant and fruit extracts have shown neuroprotective effect against neurodegenerative diseases. It has been reported that several natural compounds binding to transthyretin (TTR) can be useful in amyloidosis prevention. TTR is a
L. Ciccone+3 more
semanticscholar +1 more source
Molecular Hydrogen as a Neuroprotective Agent [PDF]
Oxidative stress and neuroinflammation cause many neurological disorders. Recently, it has been reported that molecular hydrogen (H2) functions as an antioxidant and anti-inflammatory agent. The routes of H2 administration in animal model and human clinical studies are roughly classified into three types, inhalation of H2 gas, drinking H2-dissolved ...
Masumi Iketani, Ikuroh Ohsawa
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Medicinal plants and natural products as neuroprotective agents in age-related macular degeneration
The retina may suffer neurodegenerative damages, as other tissues of the central nervous system do, and serious eye diseases may develop. One of them is age-related macular degeneration, which causes progressive loss of vision due to retina degeneration.
I. Martínez-Solís+9 more
semanticscholar +1 more source
Current neuroprotective agents in stroke [PDF]
What is expected from neuroprotection is to inhibit neuronal death and halt or decelerate the neuronal loss to lower the mortality rates, decrease disability, and improve the quality of life following an acute ischemic stroke. Several agents were described as neuroprotective up to date; however, there is still debate which to use in the ...
Yanık T, Yanık B.
europepmc +3 more sources
BackgroundRecent studies on renin-angiotensin system (RAS) inhibitors have reported a reduced risk of Alzheimer’s disease (AD). Nevertheless, the effect of RAS inhibitor type and blood–brain barrier (BBB) permeability on the risk of AD is still unknown ...
Hyun Woo Lee+7 more
doaj +1 more source
Neuroprotective Agents in Glaucoma [PDF]
1.1 Glaucoma as a neurodegenerative disorder Glaucoma is a multifactorial disease in which multiple genetic, systemic and environmental factors interact to precipitate the disease. Increased intraocular pressure (IOP) is believed to be one of the major factors responsible for glaucomatous cell death. (Guo et al., 2005).
George Kitsos, Eleni Bagli
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Background: Renin-angiotensin system (RAS) inhibitors have been suggested as protective agents in Parkinson’s disease (PD). However, epidemiological evidence on the association between RAS inhibitors and the development of PD is inconsistent.Objectives ...
Youngkwon Jo+6 more
doaj +1 more source
Ginseng polysaccharides: A potential neuroprotective agent
The treatments of nervous system diseases (NSDs) have long been difficult issues for researchers because of their complexity of pathogenesis. With the advent of aging society, searching for effective treatments of NSDs has become a hot topic. Ginseng polysaccharides (GP), as the main biologically active substance in ginseng, has various biological ...
Chunchao Han+6 more
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Anthocyanins: Plant-based flavonoid pigments with diverse biological activities
Anthocyanins are flavonoid containing polyphenolic phytochemicals. They are widely present in plants and accounts for different color shades displayed by the plant organs.
Sandip Patra+4 more
doaj
Neurodegeneration is a slow and progressive loss of neuronal cells or their function in specific regions of the brain or in the peripheral system.
Daniele Zampieri+8 more
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