Results 41 to 50 of about 3,331,814 (239)

Natural compounds as inhibitors of transthyretin amyloidosis and neuroprotective agents: analysis of structural data for future drug design

open access: yesJournal of Enzyme Inhibition and Medicinal Chemistry, 2020
Natural compounds, such as plant and fruit extracts have shown neuroprotective effect against neurodegenerative diseases. It has been reported that several natural compounds binding to transthyretin (TTR) can be useful in amyloidosis prevention. TTR is a
L. Ciccone   +3 more
semanticscholar   +1 more source

Molecular Hydrogen as a Neuroprotective Agent [PDF]

open access: yesCurrent Neuropharmacology, 2017
Oxidative stress and neuroinflammation cause many neurological disorders. Recently, it has been reported that molecular hydrogen (H2) functions as an antioxidant and anti-inflammatory agent. The routes of H2 administration in animal model and human clinical studies are roughly classified into three types, inhalation of H2 gas, drinking H2-dissolved ...
Masumi Iketani, Ikuroh Ohsawa
openaire   +2 more sources

Medicinal plants and natural products as neuroprotective agents in age-related macular degeneration

open access: yesNeural Regeneration Research, 2020
The retina may suffer neurodegenerative damages, as other tissues of the central nervous system do, and serious eye diseases may develop. One of them is age-related macular degeneration, which causes progressive loss of vision due to retina degeneration.
I. Martínez-Solís   +9 more
semanticscholar   +1 more source

Current neuroprotective agents in stroke [PDF]

open access: yesTurk J Phys Med Rehabil
What is expected from neuroprotection is to inhibit neuronal death and halt or decelerate the neuronal loss to lower the mortality rates, decrease disability, and improve the quality of life following an acute ischemic stroke. Several agents were described as neuroprotective up to date; however, there is still debate which to use in the ...
Yanık T, Yanık B.
europepmc   +3 more sources

Neuroprotective effect of angiotensin II receptor blockers on the risk of incident Alzheimer’s disease: A nationwide population-based cohort study

open access: yesFrontiers in Aging Neuroscience, 2023
BackgroundRecent studies on renin-angiotensin system (RAS) inhibitors have reported a reduced risk of Alzheimer’s disease (AD). Nevertheless, the effect of RAS inhibitor type and blood–brain barrier (BBB) permeability on the risk of AD is still unknown ...
Hyun Woo Lee   +7 more
doaj   +1 more source

Neuroprotective Agents in Glaucoma [PDF]

open access: yes, 2011
1.1 Glaucoma as a neurodegenerative disorder Glaucoma is a multifactorial disease in which multiple genetic, systemic and environmental factors interact to precipitate the disease. Increased intraocular pressure (IOP) is believed to be one of the major factors responsible for glaucomatous cell death. (Guo et al., 2005).
George Kitsos, Eleni Bagli
openaire   +3 more sources

Protective Effect of Renin-Angiotensin System Inhibitors on Parkinson’s Disease: A Nationwide Cohort Study

open access: yesFrontiers in Pharmacology, 2022
Background: Renin-angiotensin system (RAS) inhibitors have been suggested as protective agents in Parkinson’s disease (PD). However, epidemiological evidence on the association between RAS inhibitors and the development of PD is inconsistent.Objectives ...
Youngkwon Jo   +6 more
doaj   +1 more source

Ginseng polysaccharides: A potential neuroprotective agent

open access: yesJournal of Ginseng Research, 2021
The treatments of nervous system diseases (NSDs) have long been difficult issues for researchers because of their complexity of pathogenesis. With the advent of aging society, searching for effective treatments of NSDs has become a hot topic. Ginseng polysaccharides (GP), as the main biologically active substance in ginseng, has various biological ...
Chunchao Han   +6 more
openaire   +3 more sources

Anthocyanins: Plant-based flavonoid pigments with diverse biological activities

open access: yesInternational Journal of Plant Based Pharmaceuticals, 2022
Anthocyanins are flavonoid containing polyphenolic phytochemicals. They are widely present in plants and accounts for different color shades displayed by the plant organs.
Sandip Patra   +4 more
doaj  

Cytotoxicity Profiles and Neuroprotective Properties of the Novel Ifenprodil Analogues as Sigma Ligands

open access: yesMolecules, 2023
Neurodegeneration is a slow and progressive loss of neuronal cells or their function in specific regions of the brain or in the peripheral system.
Daniele Zampieri   +8 more
doaj   +1 more source

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