Results 71 to 80 of about 129,026 (254)

mGluR5 in ECCCK to BLA Circuit Modulates Depressive‐Like Phenotypes through CCK Signaling

Advanced Science, EarlyView.
Dysregulation of mGluR5 and CCK signaling contributes to major depressive disorder, yet circuit‐level mechanisms remain unclear. Here, the ECCCK→BLA pathway is identified as a critical regulator of affective behavior. mGluR5 modulates synaptic function and CCK signaling within this circuit, controlling stress susceptibility and depressive‐like states ...
Muhammad Asim, Huajie Wang, Gao Qianqian, Abdul Waris, Jufang He   +4 more
wiley   +1 more source

Neuropsychiatric symptoms and the use of complementary and alternative medicine. [PDF]

, 2013
OBJECTIVES: To assess the prevalence of complementary and alternative medicine (CAM) use by U.S. adults reporting neuropsychiatric symptoms and whether this prevalence changes based on the number of symptoms reported.
Purohit, Maulik P, MD, MPH, Phillips, Russell S, Zafonte, Ross D, Davis, Roger B, Wells, Rebecca Erwin   +4 more
core  

Long‐Term Ambient Benzene Exposure and Brain Disorders Among Urban Adults: Effect Modification by Genetic Susceptibility and Potential Mediation by Plasma Proteins

Advanced Science, EarlyView.
Low‐level ambient benzene exposure is associated with increased risks of multiple brain disorders in urban adults. Genetic susceptibility modifies these associations, while plasma proteomics points to potential biological pathways linking benzene exposure to adverse brain health.
Jianhui Guo, Xia Zhong, Petros Koutrakis, Carolina L. Zilli Vieira, Feifei Si, Yaqi Wang, Xinyao Lian, Yi Fan, Zhaokun Wang, Shaodan Huang, Jing Li   +10 more
wiley   +1 more source

Associations Between Neuropsychiatric Symptoms and Inflammation in Neurodegenerative Dementia: A Systematic Review [PDF]

Peter Swann,* Anastasia Mirza-Davies,* John O’Brien Department of Psychiatry, University of Cambridge, School of Clinical Medicine, Cambridge, UK*These authors contributed equally to this workCorrespondence: John O’Brien, Department of ...
O'Brien J, Mirza-Davies A, Swann P
core   +1 more source

Neuropsychiatric Symptoms in Patients with Idiopathic Normal Pressure Hydrocephalus [PDF]

, 2009
Objective: To clarify the characteristics of neuropsychiatric symptoms in patients with idiopathic normal pressure hydrocephalus (iNPH)
Yoshihiko Kubo, Tamiki Wada, Mamoru Hashimoto, Yumiko Kito, Hiroaki Kazui, Masahiko Takaya, Masatsune Ishikawa, Hiroji Miyake, Keiko Nomura, Shingo Ohkawa, Tetsuhiko Yoshida, Masatoshi Takeda   +11 more
core   +1 more source

Sundown syndrome in patients with Alzheimer’s disease dementia

Dementia & Neuropsychologia, 2019
The sundown syndrome is a complex neurobehavioral disorder in patients with dementia associated with high financial cost and significant caregiver burden.
Cristiani Sartorio Menegardo, Fernanda Alencar Friggi, Julia Baldon Scardini, Tais Souza Rossi, Thais dos Santos Vieira, Alessandra Tieppo, Renato Lirio Morelato   +6 more
doaj   +1 more source

Wearable‐Derived Diurnal Alignment Between Physical Activity and Device Temperature Predicts Future Disease and Mortality Risk

Advanced Science, EarlyView.
Wearable‐derived diurnal alignment between physical activity and device temperature, decomposed into 24 h coupling strength (M24), phase deviation (D24), and 12 h harmonic magnitude (M12), is examined in approximately 90,000 UK Biobank participants.
Han Chen, Jiahe Wei, Jonathan Cedernaes, Christian Benedict, Athanasios Tsanas, Zhi Cao, Xiao Tan   +6 more
wiley   +1 more source

Alleviating neuropsychiatric symptoms in dementia: the effects of Ginkgo biloba extract EGb 761®. Findings from a randomized controlled trial [PDF]

, 2011
Natalia Bachinskaya1, Robert Hoerr2, Ralf Ihl3For the GOTADAY Study Group1Institute of Gerontology, Academy of Medical Sciences, Kiev, Ukraine; 2Clinical Research Department, Dr Willmar Schwabe Pharmaceuticals, Karlsruhe, Germany; 3Geriatric Psychiatry ...
Bachinskaya N, Ihl R, Hoerr R
core  

Cognitive and Neuropsychiatric Symptom Differences in Early Stages of Alzheimer’s Disease: Kuopio ALSOVA Study

Dementia and Geriatric Cognitive Disorders Extra, 2012
Background/Aim: Alzheimer’s disease (AD) causes impairment in memory and other cognitive functions as well as neuropsychiatric symptoms and limitations in the activities of daily living (ADL).
Ilona Hallikainen, Anne M. Koivisto, Teemu Paajanen, Asta Hiltunen, Pertti Karppi, Matti Vanhanen, Tarja Välimäki, Sanna-Kaisa Herukka, Hilkka Soininen, Tuomo Hänninen   +9 more
doaj   +1 more source

Multi‐Component Functionalized Bifidobacterium Longum Hydrogel for Multi‐Target Integrated Therapy of Colitis‐Associated Anxiety and Depression

Advanced Science, EarlyView.
A pH/MMP dual‐responsive Bifidobacterium longum (BL) hydrogel (INPs@BL@Gel) functionalized with baicalin, tyrosine, and inulin is constructed. It enables gastric protection, inflammation‐targeted release, and prolonged intestinal colonization. By remodeling gut microbiota, elevating beneficial neuroactive metabolites (homovanillic acid, short‐chain ...
Shuo Zhang, Yujie Zhang, Jiansheng He, Shunlian Li, Qingyan Ma, Qiao Li, Yudan Zhang, Yiyang Wang, Shaobo Ma, Songyan Jin, Chune Li, Xueyong Xie, Hang Zhang, Junze Deng, Xueqin Song, Daocheng Wu, Xiancang Ma, Feng Zhu   +17 more
wiley   +1 more source