Results 41 to 50 of about 7,284 (241)
Small G Proteins Dexras1 and RHES and Their Role in Pathophysiological Processes
Dexras1 and RHES, monomeric G proteins, are members of small GTPase family that are involved in modulation of pathophysiological processes. Dexras1 and RHES levels are modulated by hormones and Dexras1 expression undergoes circadian fluctuations.
Ashish Thapliyal +2 more
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Activity regulated neurotransmission shapes the computational properties of a neuron and involves the concerted action of many proteins. Classical, intuitive working models often assign specific proteins to specific steps in such complex cellular ...
L Niels Cornelisse +5 more
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Differential expression of synaptophysin and synaptoporin during pre- and postnatal development of the hippocampal network [PDF]
The closely related synaptic vesicle membrane proteins synaptophysin and synaptoporin are abundant in the hippocampal formation of the adult rat. But the prenatal hippocampal formation contains only synaptophysin, which is first detected at embryonic day
Amaral +51 more
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Abstract Neuromodulatory subcortical systems (NSSs) are uniquely susceptible to dementia‐related pathology, leading to frequent molecular and behavioral impairments associated with altered function of these nuclei. Some of these systems display clear sex‐specific cytoarchitecture and signaling leading to distinct physiology and behavioral outputs in ...
Rosaria J. Rae +53 more
wiley +1 more source
Forgetting in C. elegans Is Accelerated by Neuronal Communication via the TIR-1/JNK-1 Pathway
The control of memory retention is important for proper responses to constantly changing environments, but the regulatory mechanisms underlying forgetting have not been fully elucidated. Our genetic analyses in C. elegans revealed that mutants of the TIR-
Akitoshi Inoue +7 more
doaj +1 more source
Eukaryotic 5’−3’ mRNA decay plays important roles during development and in response to stress, regulating gene expression post-transcriptionally. In Caenorhabditis elegans, deficiency of DCAP-1/DCP1, the essential co-factor of the major cytoplasmic mRNA
Fivos Borbolis +10 more
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Abstract figure legend CD73 promotes carotid body hyperactivity in chronically hypoxic animals. Exposure to chronic hypoxia (CH) (FiO2 of 12% for 10 days) increases the proportion of CD73+TH+ cells in the carotid body and induces basal chemoafferent hyperactivity.
Demitris Nathanael +4 more
wiley +1 more source
The study aimed to reveal physical exercise conditions and catecholamine response-dependent differences while an individual experiences a flow state (FS) following noncompetitive and competitive running drills.
István Karsai +8 more
doaj +1 more source
Autophagy and endolysosomal trafficking are crucial in neuronal development, function and survival. These processes ensure efficient removal of misfolded aggregation-prone proteins and damaged organelles, such as dysfunctional mitochondria, thus allowing
Silvia Giovedì +9 more
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Loss of the transcriptional repressor PAG-3/Gfi-1 results in enhanced neurosecretion that is dependent on the dense-core vesicle membrane protein IDA-1/IA-2. [PDF]
It is generally accepted that neuroendocrine cells regulate dense core vesicle (DCV) biogenesis and cargo packaging in response to secretory demands, although the molecular mechanisms of this process are poorly understood.
Tao Cai +6 more
doaj +1 more source

